Type 2 Diabetes Mellitus
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Sign up freeTop drugs studied for this disease
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FDA approval · 2016-04-05FDA Approved: ALOGLIPTIN AND PIOGLITAZONE — Supplemental Application (Padagis Israel Pharmaceuticals Ltd)
The FDA approved a supplemental application for the alogliptin benzoate and pioglitazone hydrochloride combination product from Padagis Isra…
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CLINICAL_TRIALS trial_result · 2016-04-05Clinical Trial Update: Comparison of TAK-875 (Fasiglifam) With Placebo in Participants With Type 2 Diabetes [Phase 3]
Phase 3 trial comparing Fasiglifam (TAK-875) to placebo in adults with type 2 diabetes; results were posted in April 2016.
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CLINICAL_TRIALS trial_result · 2016-04-05Clinical Trial Update: Exposure to Type II Diabetes for Two Siblings With the Same Parents
A clinical trial studying exposure to Type 2 diabetes mellitus in two siblings from the same parents has been terminated.
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CLINICAL_TRIALS trial_result · 2016-04-04Clinical Trial Update: Efficacy and Safety of TAK-875 in Combination With Sitagliptin in Participants With Type 2 Diabetes Mellitus [Phase 2]
Phase 2 trial evaluating TAK-875 in combination with sitagliptin in adults with type 2 diabetes has completed, with results reported on effi…
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CLINICAL_TRIALS trial_result · 2016-04-04Clinical Trial Update: Linagliptin as Add on Therapy to Empagliflozin 10 mg or 25 mg With Background Metformin in Patient With Type 2 Diabetes [Phase 3]
Phase 3 trial results evaluating linagliptin added to empagliflozin with background metformin in adults with type 2 diabetes have been compl…
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CLINICAL_TRIALS research · 2016-04-04Clinical Trial Update: Meta-analysis in Post-marketing Surveillances for SGLT2 Inhibitors in Patients With Type 2 Diabetes Mellitus
This document presents a meta-analysis of post-marketing surveillance data evaluating SGLT2 inhibitors in patients with Type 2 diabetes mell…
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CLINICAL_TRIALS trial_result · 2016-03-31Clinical Trial Update: Calorie Reduction Or Surgery: Seeking Remission for Obesity And Diabetes [NA]
Completed trial comparing calorie reduction versus surgery in achieving remission of obesity and type 2 diabetes.
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CLINICAL_TRIALS research · 2016-03-31Clinical Trial Update: Mechanisms of Glycemic Improvement After Gastrointestinal Surgery
A completed clinical trial investigating mechanisms of glycemic improvement after gastrointestinal surgery in Type 2 diabetes.
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CLINICAL_TRIALS trial_result · 2016-03-31Clinical Trial Update: EXIT: Prospective Study of the Response to Exercise
The EXIT trial, a prospective study evaluating the response to exercise, has completed in participants with fatty liver disease and type 2 d…
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CLINICAL_TRIALS trial_result · 2016-03-31Clinical Trial Update: Efficacy and Safety Comparative Study of Sitagliptin,Vildagliptin and Saxagliptin [NA]
A clinical trial update comparing the efficacy and safety of sitagliptin, vildagliptin, and saxagliptin in Type 2 diabetes mellitus; current…
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CLINICAL_TRIALS trial_result · 2016-03-31Clinical Trial Update: The Effectiveness of Resistance Training on Glycemic Control for Patients With Type 2 Diabetes in Cardiac Rehabilitation [NA]
A completed clinical trial evaluated the effectiveness of resistance training on glycemic control in patients with type 2 diabetes participa…
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CLINICAL_TRIALS research · 2016-03-30Clinical Trial Update: A Study of the Impact of Genetic Testing on Clinical Decision Making and Patient Care [NA]
This document provides an update on a clinical trial examining how genetic testing influences clinical decision making and patient care, spo…
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FDA approval · 2016-03-28FDA Approved: INVOKANA — Supplemental Application (Janssen Pharmaceuticals, Inc.)
The FDA approved a supplemental application for Invokana (canagliflozin) submitted by Janssen Pharmaceuticals, Inc.
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FDA approval · 2016-03-28FDA Approved: INVOKAMET — Supplemental Application (Janssen Pharmaceuticals, Inc.)
FDA Supplemental Approval for INVOKAMET (canagliflozin and metformin hydrochloride) by Janssen Pharmaceuticals, Inc. The action approves a l…
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CLINICAL_TRIALS trial_result · 2016-03-28Clinical Trial Update: Study of Two Titration Algorithms With Insulin Glargine 300 Units/mL in Type 2 Diabetes Mellitus Patients [Phase 3]
Sanofi reports the completion of a Phase 3 trial evaluating two titration algorithms for insulin glargine 300 units/mL in adults with Type 2…
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CLINICAL_TRIALS withdrawal · 2016-03-28Clinical Trial Update: A Study of Insulin Peglispro (LY2605541) in Participants With Type 2 Diabetes Mellitus [Phase 3]
Phase 3 clinical trial of insulin peglispro (LY2605541) for type 2 diabetes mellitus has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-03-28Clinical Trial Update: A Multiple Ascending Dose Phase I Study of DBPR108 in Healthy Male Subjects [Phase 1]
Phase 1 multiple ascending dose study of DBPR108 in healthy male subjects completed; the trial lists Type 2 diabetes mellitus as the conditi…
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CLINICAL_TRIALS research · 2016-03-25Clinical Trial Update: Effect of SGLT-2 Inhibitor Dapagliflozin on Glycemic Variability in Patients With Diabetes Mellitus Type 2 [Phase 4]
This document summarizes a Phase 4 clinical trial evaluating dapagliflozin, an SGLT-2 inhibitor, for reducing glycemic variability in adults…
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CLINICAL_TRIALS research · 2016-03-25Clinical Trial Update: An Observational, Cross Sectional Study to Assess the Prevalence of Chronic Kidney Disease (CKD) in Type 2 Diabetes Patients
An observational cross-sectional study sponsored by AstraZeneca assessed how common chronic kidney disease is among patients with type 2 dia…
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FDA approval · 2016-03-24FDA Approved: ACARBOSE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
The FDA approved a supplemental application for ACARBOSE from Hikma Pharmaceuticals USA Inc.
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CLINICAL_TRIALS trial_result · 2016-03-24Clinical Trial Update: Influence of Liraglutide, a GLP-1 Receptor Agonist, on Brown Adipose Tissue (BAT) Activity in Humans [Phase 3]
This Phase 3 trial investigates whether liraglutide influences brown adipose tissue activity in adults with obesity and type 2 diabetes; the…
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CLINICAL_TRIALS trial_result · 2016-03-23Clinical Trial Update: Vildagliptin/Metformin in T2DM Patients Starting Basal Insulin [Phase 3]
Phase 3 clinical trial update on combining vildagliptin with metformin for Type 2 Diabetes Mellitus patients starting basal insulin; results…
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CLINICAL_TRIALS trial_result · 2016-03-23Clinical Trial Update: A Phase IIIb Study to Evaluate the Safety and Efficacy of Gemigliptin in Type 2 Diabetes Mellitus Patients With Moderate or Severe Renal Impairment(GUARD Study) [Phase 3]
Phase IIIb study evaluating the safety and efficacy of gemigliptin in adults with Type 2 diabetes mellitus and moderate-to-severe renal impa…
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CLINICAL_TRIALS trial_result · 2016-03-23Clinical Trial Update: Dose-Response and Variability of Inhaled Insulin in Type 2 Diabetes [Phase 1, Phase 2]
Phase 1/2 trials evaluated dose-response and variability of inhaled insulin in Type 2 Diabetes Mellitus and have completed.
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CLINICAL_TRIALS trial_result · 2016-03-23Clinical Trial Update: A Radiolabeled Mass Balance Study of [14C]-Ertugliflozin (PF04971729, MK-8835) In Healthy Male Participants (MK-8835-038) [Phase 1]
Phase 1 radiolabeled mass balance study of [14C]-ertugliflozin (MK-8835) in healthy male participants has completed. The trial examined phar…