Type 2 Diabetes Mellitus
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2016-07-06Clinical Trial Update: High Protein Breakfast on Appetite, Postprandial Glycemia and Weight Loss in T2D [NA]
This clinical trial update examines whether a high-protein breakfast affects appetite, postprandial glycemia, and weight in people with Type…
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FDA approval · 2016-07-06FDA Approved: NATEGLINIDE — Original Application (Zydus Lifesciences Limited)
FDA approved Zydus Lifesciences Limited's original application for nateglinide, a meglitinide insulin secretagogue, for the treatment of typ…
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CLINICAL_TRIALS trial_result · 2016-07-04Clinical Trial Update: Safety, Tolerability and Efficacy of ISIS-GCGRRx in Type 2 Diabetes [Phase 2]
This trial update reports on a Phase 2 study of ISIS-GCGRRx in Type 2 Diabetes, focusing on safety, tolerability, and preliminary efficacy.
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CLINICAL_TRIALS research · 2016-07-04Clinical Trial Update: the Food Effect Pharmacokinetic, Material Balance and Metabolite Identification of SP2086 in Healthy Volunteers [Phase 1]
Phase 1 clinical trial update evaluating the effect of food on the pharmacokinetics, material balance, and metabolite identification of SP20…
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CLINICAL_TRIALS trial_result · 2016-07-04Clinical Trial Update: The Pharmacokinetics and Pharmacodynamics Study of Single and Multiple Dose of SP2086 in Type 2 Diabetes Patients [Phase 1]
Phase 1 pharmacokinetics and pharmacodynamics study assessing single and multiple doses of SP2086 in adults with type 2 diabetes. The public…
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CLINICAL_TRIALS trial_result · 2016-07-01Clinical Trial Update: Efficacy and Safety of Switching From Sitagliptin to Liraglutide in Subjects With Type 2 Diabetes Not Achieving Adequate Glycaemic Control on Sitagliptin and Metformin [Phase 4]
Phase 4 trial evaluating switching from sitagliptin to liraglutide in type 2 diabetes patients not achieving glycemic control on sitagliptin…
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CLINICAL_TRIALS trial_result · 2016-07-01Clinical Trial Update: The Metabolite Identification and Material Balance Study of SP2086 [Phase 1]
This update covers a Phase 1 metabolite identification and material balance study of SP2086 for Type 2 diabetes mellitus, sponsored by Jiang…
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CLINICAL_TRIALS trial_result · 2016-06-29Clinical Trial Update: The DDI Study of SP2086 and Simvastatin [Phase 1]
A Phase 1 clinical trial update reporting a drug-drug interaction study between SP2086 and simvastatin in Type 2 diabetes mellitus.
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CLINICAL_TRIALS trial_result · 2016-06-29Clinical Trial Update: A Trial Comparing the Glycaemic Control of Levemir® Administered Once Daily According to Two Insulin Detemir Titration Algorithms After 20 Weeks in Subjects With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin Treatment With or Without Other Anti-diabetic Drugs (OADs) [Phase 4]
Phase 4 study comparing two titration algorithms for once-daily insulin detemir over 20 weeks in adults with Type 2 diabetes inadequately co…
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CLINICAL_TRIALS research · 2016-06-29Clinical Trial Update: The DDI Study of SP2086 and Valsartan [Phase 1]
Phase 1 clinical trial update reporting a drug-drug interaction study between SP2086 and valsartan in individuals with type 2 diabetes.
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CLINICAL_TRIALS trial_result · 2016-06-28Clinical Trial Update: The Drug-drug Interaction of SP2086 and Valsartan [Phase 1]
This Phase 1 study evaluated the drug-drug interaction between SP2086 and valsartan in individuals with type 2 diabetes mellitus and has com…
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CLINICAL_TRIALS trial_result · 2016-06-28Clinical Trial Update: The Drug -Drug Interaction of SP2086 and Glyburide [Phase 1]
Phase 1 trial investigating the drug-drug interaction between SP2086 and glyburide has completed.
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CLINICAL_TRIALS trial_result · 2016-06-28Clinical Trial Update: The Drug-drug Interaction of SP2086 and Simvastatin [Phase 1]
This Phase 1 trial evaluated potential drug-drug interactions between SP2086 and simvastatin in patients with type 2 diabetes mellitus. The …
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CLINICAL_TRIALS trial_result · 2016-06-27Clinical Trial Update: The Drug-drug Interaction of SP2086 and Metformin [Phase 1]
A Phase 1 study evaluating the drug–drug interaction between SP2086 and metformin in adults with type 2 diabetes mellitus has been completed…
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CLINICAL_TRIALS trial_result · 2016-06-27Clinical Trial Update: Sucralose in Subjects With Diabetes Mellitus Insulin Requesting [NA]
A completed clinical trial evaluated sucralose in subjects with Type 2 diabetes mellitus who require insulin.
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FDA label_change · 2016-06-24FDA Approved: TRESIBA — Supplemental Application (Novo Nordisk)
The FDA approved a supplemental application for Tresiba (insulin degludec) from Novo Nordisk, resulting in a labeling change.
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CLINICAL_TRIALS trial_result · 2016-06-23Clinical Trial Update: A Phase I Study to Assess the Pharmacodynamics of Oral AR-C165395XX in Subjects With Type 2 Diabetes Mellitus (T2DM) [Phase 1]
Phase I pharmacodynamics study of an oral AR-C165395XX in subjects with Type 2 Diabetes Mellitus. Results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-06-23Clinical Trial Update: Chronic Cold Acclimation Stimulates the Browning of Subcutaneous White Adipose in Patients With Type 2 Diabetes Mellitus [Phase 4]
Phase 4 clinical trial investigates chronic cold acclimation and its effect on browning of subcutaneous white adipose tissue in people with …
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CLINICAL_TRIALS trial_result · 2016-06-22Clinical Trial Update: Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus [Phase 2]
Phase 2 trial update reporting efficacy and safety results for SYR-472 in adults with Type 2 diabetes mellitus.
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CLINICAL_TRIALS trial_result · 2016-06-22Clinical Trial Update: Efficacy and Safety of TAK-379 in Adult Subjects With Type 2 Diabetes Mellitus [Phase 2]
Phase 2 trial update evaluating the efficacy and safety of TAK-379 in adults with type 2 diabetes mellitus; the study was terminated.
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CLINICAL_TRIALS trial_result · 2016-06-22Clinical Trial Update: Does Pioglitazone Increase the Production of 15-EPI-Lipoxin A4? [Phase 4]
A Phase 4 trial update investigates whether pioglitazone increases production of 15-EPI-Lipoxin A4 in individuals with Type 2 Diabetes Melli…
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CLINICAL_TRIALS trial_result · 2016-06-22Clinical Trial Update: Efficacy of SYR-472 in Subjects With Type 2 Diabetes Mellitus [Phase 2]
Phase 2 trial evaluating the efficacy of SYR-472 in adults with Type 2 diabetes mellitus has completed and results have been updated.
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CLINICAL_TRIALS research · 2016-06-22Clinical Trial Update: Defining the Physiological Mechanisms of Risk Genes for Hyperglycaemia, Insulin Resistance and Type 2 Diabetes
An update on a University of Oxford clinical study investigating how genetic risk factors contribute to hyperglycemia, insulin resistance an…
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CLINICAL_TRIALS research · 2016-06-22Clinical Trial Update: Interval-training and Appetite Regulation in Patients With Type 2 Diabetes [NA]
This is a clinical trial update exploring interval-training and appetite regulation in adults with Type 2 diabetes. The current trial status…
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CLINICAL_TRIALS research · 2016-06-22Clinical Trial Update: Optimization of Interval-training in Patients With Type 2 Diabetes [NA]
An update on a clinical trial studying the optimization of interval-training in adults with type 2 diabetes; the trial status is unknown.