Type 2 Diabetes Mellitus

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Titration Study of a Glucagon-Like Peptide-1 (GLP-1) Analogue in Patients With Type 2 Diabetes Treated With Metformin. [Phase 2]

  Phase 2 titration study of the GLP-1 analogue taspoglutide in patients with type 2 diabetes mellitus on metformin; the trial has completed.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study on The Potential of Aleglitazar to Reduce Cardiovascular Risk in Patients With Stable Cardiovascular Disease and Glucose Abnormalities [Phase 3]

  Phase 3 study of Aleglitazar for reducing cardiovascular risk in stable cardiovascular disease with Type 2 diabetes mellitus has completed.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of DPP-IV Inhibitor in Patients With Type 2 Diabetes [Phase 2]

  A completed Phase 2 study evaluated a DPP-IV inhibitor in patients with type 2 diabetes.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of Taspoglutide in Patients With Inadequately Controlled Diabetes Mellitus Type 2 and Cardiovascular Disease [Phase 3]

  This document provides an update on a Phase 3 clinical trial of taspoglutide in patients with inadequately controlled Diabetes Mellitus Type…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Safety, Pharmacokinetics and Pharmacodynamics Study of RO6811135 in Patients With Type 2 Diabetes Mellitus [Phase 1]

  This document reports the completion of a Phase 1 safety, pharmacokinetics and pharmacodynamics study of RO6811135 in patients with Type 2 d…

• Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Drug-Drug Interaction Study of GK Activator (2) and Glyburide in Patients With Type 2 Diabetes. [Phase 1]

  Phase 1 study assessing drug-drug interaction between GK Activator (2) and glyburide in adults with type 2 diabetes; the trial has completed…

• CLINICAL_TRIALS withdrawal · 2016-11-02
  Clinical Trial Update: A Study of Alegitazar in Patients With Type 2 Diabetes And Chronic Kidney Disease (Alerenal Study) [Phase 3]

  A Phase 3 trial of Alegitazar in patients with Type 2 diabetes mellitus and chronic kidney disease has been withdrawn.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of a GLP-1 Analogue in Patients With Type 2 Diabetes Treated With Metformin. [Phase 2]

  Roche completed a Phase 2 trial evaluating a GLP-1 analogue (taspoglutide) in patients with Type 2 diabetes mellitus treated with metformin.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of Aleglitazar in Monotherapy in Patients With Type 2 Diabetes Mellitus Who Are Drug-Naïve to Anti-Hyperglycemic Therapy [Phase 3]

  Phase 3 trial evaluating aleglitazar as monotherapy in drug-naïve patients with Type 2 diabetes mellitus has completed.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of the Effect of Taspoglutide on Gastric Emptying in Patients With Type 2 Diabetes [Phase 3]

  Phase 3 trial investigating the effect of taspoglutide on gastric emptying in patients with Type 2 diabetes; the study status is completed.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of Taspoglutide Versus Pioglitazone in Patients With Type 2 Diabetes [Phase 3]

  Phase 3 trial comparing taspoglutide with pioglitazone in patients with type 2 diabetes has completed.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Multiple Ascending Dose Study of R1511 in Patients With Type 2 Diabetes Mellitus. [Phase 1]

  The study updates the completion of a Phase 1 multiple ascending dose trial evaluating R1511 in patients with Type 2 diabetes mellitus.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of RO5095932 in Patients With Type 2 Diabetes Mellitus [Phase 1]

  This is a Phase 1 clinical trial update for RO5095932 in Type 2 diabetes mellitus. The study status is reported as completed.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of The Effect of Aleglitazar on Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin [Phase 2]

  Phase 2 study evaluating the effect of Aleglitazar on insulin sensitivity in patients with Type 2 diabetes mellitus inadequately controlled …

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of GK Activator (2) in Patients With Type 2 Diabetes Mellitus [Phase 2]

  Phase 2 study of GK Activator (2) in patients with Type 2 diabetes mellitus has completed.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of the Effect of Renal Impairment on the Activity of GK Activator (2) in Patients With Type 2 Diabetes. [Phase 1]

  This clinical trial update reports the completion of a Phase 1 study by Hoffmann-La Roche evaluating how renal impairment affects the activi…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of Single Doses of RO4998452 in Patients With Type 2 Diabetes [Phase 1]

  A Phase 1 study evaluating single doses of RO4998452 in patients with Type 2 diabetes has completed.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of Aleglitazar in Patients With Type 2 Diabetes [Phase 2]

  Phase 2 clinical trial of Aleglitazar in patients with Type 2 diabetes mellitus has completed.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: Japanese Primary Prevention of Atherosclerosis With Aspirin for Diabetes (JPAD) Trial [Phase 4]

  This document reports the completion status of the JPAD Phase 4 trial evaluating aspirin for primary prevention of atherosclerosis in people…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of DPP-IV Inhibitor in Patients With Type 2 Diabetes [Phase 2]

  Phase 2 clinical trial update from Hoffmann-La Roche evaluating a DPP-4 inhibitor in patients with Type 2 diabetes has completed.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: Adult Accuracy Study of the Enlite 3 Glucose Sensor [NA]

  Completed adult accuracy study of the Enlite 3 glucose sensor in people with Type 1 or Type 2 diabetes; results have been posted.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Multiple Ascending Dose Study of RO4998452 in Patients With Type 2 Diabetes Mellitus. [Phase 1]

  A completed Phase 1 multiple ascending dose study of Roche compound RO4998452 in patients with Type 2 diabetes mellitus.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus [Phase 3]

  A Phase 3 study of aleglitazar in patients with a recent acute coronary syndrome and type 2 diabetes mellitus has completed.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study With RO5095932 in Patients With Type 2 Diabetes on Stable Metformin Therapy. [Phase 1]

  A Phase 1 study evaluating RO5095932 in patients with Type 2 diabetes mellitus on stable metformin therapy has completed.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Pharmacodynamic/Pharmacokinetic Study of Aleglitazar in Patients With Type 2 Diabetes Mellitus on Treatment With Lisinopril [Phase 1]

  This Phase 1 trial reports pharmacodynamic and pharmacokinetic data for aleglitazar in patients with type 2 diabetes mellitus who are on lis…