Type 2 Diabetes Mellitus
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CLINICAL_TRIALS trial_result · 2017-02-20Clinical Trial Update: Effect of Repaglinide on Postprandial Lipemia in Type 2 Diabetes [Phase 4]
A Phase 4 clinical trial assessed the effect of repaglinide on postprandial lipemia in adults with type 2 diabetes; the study has completed.
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CLINICAL_TRIALS trial_result · 2017-02-20Clinical Trial Update: Post Marketing Study in Subjects Who Have Type 2 Diabetes Using the EndoBarrier™ Gastrointestinal Liner [NA]
Post-marketing study results for the EndoBarrier Gastrointestinal Liner in subjects with Type 2 diabetes mellitus and obesity; the study is …
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CLINICAL_TRIALS trial_result · 2017-02-17Clinical Trial Update: The Efficacy of Insulin Degludec/Liraglutide as add-on Therapy in Controlling Glycaemia in Adults With Type 2 Diabetes Inadequately Controlled on Sulphonylurea With or Without Metformin Therapy [Phase 3]
A Phase 3 trial assessed the efficacy of the fixed-dose combination insulin degludec/liraglutide as add-on therapy to improve glycemic contr…
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CLINICAL_TRIALS trial_result · 2017-02-17Clinical Trial Update: Phase II Safety and Efficacy Study of Oral ORMD-0801 in Patients With Type 2 Diabetes Mellitus [Phase 2]
Phase II safety and efficacy study of oral ORMD-0801 in type 2 diabetes completed with posted results.
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CLINICAL_TRIALS trial_result · 2017-02-17Clinical Trial Update: TRANSforming InTerprofessional Cardiovascular Prevention in Primary Care [NA]
Clinical trial update for the TRANSforming InTerprofessional Cardiovascular Prevention in Primary Care trial (NCT01418716) with completed st…
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CLINICAL_TRIALS trial_result · 2017-02-17Clinical Trial Update: GLP-1 and Microvascular Function in Type 2 Diabetes [NA]
This update notes the completed clinical trial investigating the effects of GLP-1 on microvascular function in people with Type 2 diabetes m…
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CLINICAL_TRIALS trial_result · 2017-02-16Clinical Trial Update: A 6-Week Study Of PF-05175157 In Type 2 Diabetes Mellitus [Phase 2]
A Phase 2 6-week study of PF-05175157 in Type 2 diabetes was terminated, but results have been posted.
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CLINICAL_TRIALS research · 2017-02-16Clinical Trial Update: Using Mobile Phone Short Message Service (SMS) Reminders to Enhance Appointment Attendance in DM Patients [NA]
This entry discusses a clinical trial evaluating whether SMS reminders can improve appointment attendance among patients with Type 2 diabete…
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FDA approval · 2017-02-15FDA Approved: KAZANO — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
The FDA approved a supplemental application for Kazano, a fixed-dose combination of alogliptin and metformin hydrochloride, from Takeda Phar…
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CLINICAL_TRIALS research · 2017-02-15Clinical Trial Update: Anatomical and Physiological Characterisation of the Gut Endocrine Cells in Healthy and in Patients With Type 2 Diabetes [NA]
This document reports an update on a clinical trial studying the anatomical and physiological characteristics of gut endocrine cells in heal…
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CLINICAL_TRIALS trial_result · 2017-02-15Clinical Trial Update: Effect of SCH 497079 on Metabolic Parameters and Influence of Race/Ethnic Origin on Therapeutic Response (Study P05338)(COMPLETED) [Phase 1]
Phase 1 trial evaluating SCH 497079 on metabolic parameters with consideration of race/ethnic origin in adults with Type 2 Diabetes Mellitus…
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CLINICAL_TRIALS trial_result · 2017-02-14Clinical Trial Update: Investigation of the Effect of E.-Coli-Nissle as Supporting Therapy to Standard Care of Diabetes Mellitus Type II [Phase 3]
A Phase 3 trial evaluating Escherichia coli Nissle 1917 as supportive therapy to standard care for Type 2 diabetes mellitus has completed.
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CLINICAL_TRIALS trial_result · 2017-02-14Clinical Trial Update: Clinical Trial for PB-119 in Healthy Subjects (Phase I) [Phase 1]
A Phase I clinical trial of PB-119 in healthy subjects sponsored by PegBio Co., Ltd. has completed, with Type 2 diabetes listed as the condi…
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CLINICAL_TRIALS trial_result · 2017-02-14Clinical Trial Update: Glycemic and Insulinemic Response With Different Sources of Soluble Fiber in Patients Type 2 Diabetes Mellitus [NA]
A completed clinical trial evaluating glycemic and insulinemic responses to different sources of soluble fiber in adults with type 2 diabete…
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CLINICAL_TRIALS trial_result · 2017-02-13Clinical Trial Update: Observational Study on Efficacy and Safety of Liraglutide in Subjects With Type 2 Diabetes
An observational study evaluating the efficacy and safety of liraglutide in adults with type 2 diabetes has completed. The study was sponsor…
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CLINICAL_TRIALS trial_result · 2017-02-13Clinical Trial Update: Observational Study to Evaluate the Safety of Levemir® in Type 2 Diabetes
An observational study evaluating the safety of Levemir (insulin detemir) in adults with type 2 diabetes has completed.
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CLINICAL_TRIALS withdrawal · 2017-02-13Clinical Trial Update: IL-1RA, Acute Exercise, and Beta-cell Function [NA]
A clinical trial evaluating interleukin-1 receptor antagonist (anakinra) effects on beta-cell function during acute exercise in people with …
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Efficacy and Safety of Insulin Glargine/Lixisenatide Fixed Combination Versus Insulin Glargine Alone on Top of Metformin in Type 2 Diabetic Patients [Phase 2]
Phase 2 trial comparing the fixed-dose combination insulin glargine/lixisenatide to insulin glargine alone, both added to metformin, in type…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Add Glucokinase Activator to Target A1c [Phase 2]
Phase 2 study update on vTv Therapeutics' glucokinase activator TTP399 aimed at lowering HbA1c in type 2 diabetes; the trial has completed.
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Efficacy and Safety of Insulin Glargine/ Lixisenatide Fixed Ratio Combination Compared to Insulin Glargine Alone and Lixisenatide Alone on Top of Metformin in Patients With T2DM [Phase 3]
Phase 3 trial evaluating the efficacy and safety of a fixed-ratio insulin glargine/lixisenatide combination versus insulin glargine alone an…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: A Study to Evaluate Safety and Efficacy of TTP273 for 12 Weeks in Subjects With Type 2 Diabetes [Phase 2]
A Phase 2 clinical trial evaluating the safety and efficacy of TTP273 in Type 2 Diabetes Mellitus has completed.
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Glycemic Efficacy and Renal Safety Study of Dapagliflozin in Subjects With Type 2 Diabetes Mellitus and Moderate Renal Impairment [Phase 2, Phase 3]
This completed study assessed the glycemic efficacy and renal safety of dapagliflozin in subjects with type 2 diabetes mellitus and moderate…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination Versus Insulin Glargine in Patients With Type 2 Diabetes [Phase 3]
This report summarizes a Phase 3 trial comparing the fixed-ratio insulin glargine/lixisenatide combination with insulin glargine in adults w…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Single Dose Pharmacokinetics of Repaglinide, Metformin and Combination Tablet in Fed Healthy Volunteers [Phase 1]
Phase 1 pharmacokinetic study of repaglinide, metformin, and a repaglinide/metformin combination tablet in fed healthy volunteers. The updat…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Effect of Repaglinide and Metformin Combination Tablet or Rosiglitazone and Metformin in Fixed Dose Combination on Blood Glucose Control in Patients With Type 2 Diabetes [Phase 3]
Phase 3 clinical trial comparing repaglinide/metformin versus rosiglitazone/metformin fixed-dose combinations for blood glucose control in t…