Type 2 Diabetes Mellitus
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CLINICAL_TRIALS trial_result · 2017-04-24Clinical Trial Update: Sitagliptin vs. Pioglitazone as add-on Treatments in Patients With Type 2 Diabetes Uncontrolled on the Full-dose Metformin Plus Sulfonylurea [Phase 3]
Phase 3 trial comparing sitagliptin vs pioglitazone as add-on therapy in adults with type 2 diabetes mellitus uncontrolled on metformin plus…
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CLINICAL_TRIALS trial_result · 2017-04-24Clinical Trial Update: Trial on Safety & Performance of TAXUS Element vs. XIENCE Prime Stent in Treatment of Coronary Lesion in Diabetics [NA]
A completed clinical trial comparing the safety and performance of TAXUS Element against XIENCE Prime stents in diabetic patients with coron…
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CLINICAL_TRIALS research · 2017-04-24Clinical Trial Update: The Role of Amylin and Incretins on Postprandial Metabolisms in Adolescents With Type 2 Diabetes Mellitus (T2DM).
This clinical trial update investigates how amylin and incretin hormones influence postprandial metabolism in adolescents with Type 2 diabet…
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CLINICAL_TRIALS research · 2017-04-24Clinical Trial Update: Single Loop DJB Sleeve Gastrectomy for Poorly Controlled T2DM [NA]
This entry provides a clinical trial update on a single-loop DJB Sleeve Gastrectomy for patients with poorly controlled Type 2 diabetes mell…
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CLINICAL_TRIALS trial_result · 2017-04-21Clinical Trial Update: Liraglutide and a Calorie Restricted Diet Augments Weight Loss and Decreases Risk of Type 2 Diabetes and CVD. [Phase 3]
Phase 3 trial found that adding liraglutide to a calorie-restricted diet led to greater weight loss and reduced risk factors for type 2 diab…
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CLINICAL_TRIALS trial_result · 2017-04-20Clinical Trial Update: Sitagliptin Improved Beta Cell Function and Prevented a Conversion Rate to Impaired Glucose Tolerance and Type 2 Diabetes in Metformin Intolerant Obese Women With Polycystic Ovary Syndrome [Phase 4]
Phase 4 trial indicates sitagliptin improved beta cell function and reduced progression to impaired glucose tolerance and type 2 diabetes in…
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CLINICAL_TRIALS trial_result · 2017-04-20Clinical Trial Update: CCK1R Function in Patient Leukocytes
Completed clinical trial evaluating cholecystokinin 1 receptor (CCK1R) function in leukocytes of patients with obesity and type 2 diabetes m…
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CLINICAL_TRIALS withdrawal · 2017-04-20Clinical Trial Update: Hartmann's Solution and Normal Saline in Type II Diabetes Patients [NA]
A clinical trial comparing Hartmann's Solution to Normal Saline in adults with type 2 diabetes has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-04-19Clinical Trial Update: Mindfulness: a Novel Approach for the Management of Diabetes-related Distress [NA]
This completed clinical trial examined mindfulness as a novel approach to reducing diabetes-related distress in adults with Type 2 diabetes.
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CLINICAL_TRIALS trial_result · 2017-04-19Clinical Trial Update: Examining The Role of CGM in T2DM [NA]
This clinical trial update reports on a study examining the role of continuous glucose monitoring in type 2 diabetes mellitus. The trial sta…
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FDA approval · 2017-04-18FDA Approved: GLIPIZIDE — Supplemental Application (Apotex Corp.)
FDA approved a supplemental application for glipizide from Apotex Corp., enabling the continued marketing of this generic antidiabetic medic…
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CLINICAL_TRIALS trial_result · 2017-04-18Clinical Trial Update: Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Saxagliptin as Monotherapy in Pediatric Patients With Type 2 Diabetes [Phase 3]
Phase 3 study evaluating Saxagliptin as monotherapy in pediatric patients with Type 2 diabetes completed, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-04-18Clinical Trial Update: A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Saxagliptin (BMS-477118) in Combination With Metformin IR or Metformin XR in Pediatric Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Alone [Phase 3]
A Phase 3 randomized, double-blind trial assessed the efficacy and safety of saxagliptin in combination with metformin (IR or XR) in pediatr…
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CLINICAL_TRIALS trial_result · 2017-04-18Clinical Trial Update: A Safety and Pharmacokinetic Study of CVX-096 in Type 2 Diabetics [Phase 1]
Phase 1 safety and pharmacokinetic study of CVX-096 in adults with Type 2 diabetes mellitus has completed, with results posted.
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CLINICAL_TRIALS research · 2017-04-17Clinical Trial Update: Meta-analyses of the Effect of 'Catalytic' Doses of Fructose and Its Epimers on Carbohydrate Metabolism
Meta-analyses evaluate the effects of catalytic doses of fructose and its epimers on carbohydrate metabolism in people with overweight/obesi…
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: Effect of Nutritional Products in Subjects With Type 2 Diabetes [NA]
This document reports the completion of a clinical trial evaluating the effect of nutritional products in subjects with type 2 diabetes, spo…
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CLINICAL_TRIALS trial_result · 2017-04-14Clinical Trial Update: START-J: SiTAgliptin in eldeRly Trial in Japan [NA]
This trial update reports the completion of a study in elderly Japanese patients with Type 2 diabetes treated with sitagliptin, with results…
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CLINICAL_TRIALS trial_result · 2017-04-14Clinical Trial Update: Exercise and Cardiovascular Control During Upright Tilt in Older Adults With Type 2 Diabetes [NA]
This update notes the completion of a University of British Columbia–sponsored clinical trial that studied how exercise affects cardiovascul…
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CLINICAL_TRIALS trial_result · 2017-04-14Clinical Trial Update: 24-Week, Multicenter, Randomized, Parallel-group, Open-label, Active Controlled Phase IV Study to Assess the Efficacy, Safety and Tolerability of Saxagliptin Compared With Acarbose When in Combination With Metformin in Patients With T2D Inadequately Controlled With Metformin Monotherapy [Phase 4]
This Phase IV multicenter randomized open-label study compared saxagliptin to acarbose as add-on to metformin in patients with Type 2 Diabet…
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CLINICAL_TRIALS trial_result · 2017-04-14Clinical Trial Update: An Evaluation of a Novel Glucose Sensing Technology in Type 2 Diabetes [NA]
A completed clinical trial evaluated Abbott Diabetes Care's novel glucose-sensing technology for Type 2 Diabetes, with results posted in 201…
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CLINICAL_TRIALS research · 2017-04-14Clinical Trial Update: Home-Based Walking Study in Older Adults With Type 2 Diabetes [NA]
A ClinicalTrials.gov update indicates a home-based walking study in older adults with Type 2 diabetes has completed, with considerations of …
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: Study on Incidence of Diabetic Ketoacidosis Among Participants With Type 2 Diabetes Mellitus Treated With Sodium-glucose Co-transporter 2 (SGLT2) Inhibitors or Other Antihyperglycemic Agents
This completed clinical trial update examines the incidence of diabet ic ketoacidosis in participants with type 2 diabetes treated with SGLT…
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: Alogliptin Tablets Special Drug Use Surveillance Type 2 Diabetes Mellitus: Combination Therapy With Sulfonylurea
Results from a Takeda-sponsored Special Drug Use Surveillance study evaluate alogliptin tablets in combination with a sulfonylurea for type …
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: Alogliptin Tablets Special Drug Use Surveillance Type 2 Diabetes Mellitus: Combination Therapy With Biguanides
A completed Special Drug Use Surveillance trial evaluated alogliptin in combination with biguanides for type 2 diabetes mellitus. Results we…
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: The Microvascular Function of GLP-1 and Its Analogues [NA]
A completed clinical trial update examining the microvascular effects of GLP-1 and its analogues in individuals with Type 2 diabetes mellitu…