Type 2 Diabetes Mellitus
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: A Study of IBI362 in Poorly Controlled Type 2 Diabetes Patients Only Through Diet and Exercise [Phase 3]
A Phase 3 trial evaluating IBI362 in adults with poorly controlled Type 2 diabetes mellitus managed by diet and exercise has completed.
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CLINICAL_TRIALS research · 2024-08-19Clinical Trial Update: A Trial Investigating the Efficacy and Safety of Insulin Degludec/Liraglutide Injection in Subjects With Type 2 Diabetes [Phase 3]
A Phase 3 trial investigating the efficacy and safety of a fixed-dose combination of insulin degludec and liraglutide in adults with Type 2 …
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CLINICAL_TRIALS research · 2024-08-19Clinical Trial Update: A Trial Comparing Efficacy, Tolerability, and Safety of GZR101 Injection Once Daily (OD) and GZR33-70 Injection OD [Phase 2]
A Phase 2 trial comparing GZR101 Injection OD and GZR33-70 Injection OD for Type 2 diabetes is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-08-19Clinical Trial Update: Type 2 Diabetes Prevention in Community Health Care Settings for at Risk Children and Mothers [NA]
This trial update notes that a study on preventing Type 2 diabetes in at-risk children and mothers in community health care settings has bee…
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CLINICAL_TRIALS research · 2024-08-16Clinical Trial Update: In-Person Lifestyle Program for Black Adolescent Girls at Risk for Type 2 Diabetes [NA]
A clinical trial from Cornell University evaluating an in-person lifestyle program to reduce the risk of type 2 diabetes in Black adolescent…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: A Crossover Study to Evaluate the Efficacy of Simvastatin in Elevating HDL-C Levels in Patients With Type 2 Diabetes (0733-216)(COMPLETED) [Phase 3]
A completed Phase 3 crossover study evaluating whether simvastatin elevates HDL cholesterol in patients with type 2 diabetes mellitus.
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Eze/Simva Switch Study in Diabetics (0653A-807) [Phase 3]
Phase 3 trial evaluating switching between ezetimibe and simvastatin in adults with Type 2 diabetes has been completed.
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: A Multicenter Study to Evaluate the Cholesterol Lowering Effects of Two Marketed Products in Patients With Type 2 Diabetes Mellitus and Hypercholesterolemia (MK-0653A-077) [Phase 3]
Phase 3 multicenter trial completed to evaluate the cholesterol-lowering effects of two marketed products in patients with Type 2 diabetes m…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Couple-Based Lifestyle Intervention to Prevent Type 2 Diabetes [NA]
Completed clinical trial evaluating a couple-based lifestyle intervention to prevent type 2 diabetes in people with prediabetes and obesity.
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: HYZAAR vs. Ramipril for Diabetes (0954A-245)(COMPLETED) [Phase 3]
A Phase 3 trial comparing HYZAAR (losartan/hydrochlorothiazide) with ramipril in patients with type 2 diabetes and hypertension has complete…
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CLINICAL_TRIALS research · 2024-08-15Clinical Trial Update: Semaglutide's Effect on Renal Hemodynamics and Function in Patients With Type 2 Diabetes Mellitus and Nephropathy [NA]
This clinical trial update describes a study investigating the effect of semaglutide on renal hemodynamics and function in patients with typ…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Study Evaluating the Efficacy and Safety of Simvastatin Alone Compared With Simvastatin Plus Ezetimibe in Type 2 Diabetic Patients (0653-021)(COMPLETED) [Phase 3]
A Phase 3 clinical trial comparing simvastatin alone with simvastatin plus ezetimibe in adults with type 2 diabetes has completed.
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CLINICAL_TRIALS trial_result · 2024-08-14Clinical Trial Update: A Trial Investigating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GZR4 in Subjects With Type 2 Diabetes [Phase 1]
This Phase 1 trial update reports completion of a study evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of GZR4 i…
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CLINICAL_TRIALS trial_result · 2024-08-14Clinical Trial Update: A Phase I Study of GZR18 Injection in Healthy Subjects [Phase 1]
A Phase I trial of GZR18 Injection in healthy subjects has completed, sponsored by Gan and Lee Pharmaceuticals (USA), investigating Type 2 d…
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CLINICAL_TRIALS trial_result · 2024-08-14Clinical Trial Update: Extension for Community Health Outcomes (ECHO) Diabetes Program [NA]
A clinical trial update announcing the completion of the Extension for Community Health Outcomes (ECHO) Diabetes Program trial sponsored by …
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Effect of Pioglitazone on Mitochondrial Function in Muscle and Adipose Tissue in Humans
This clinical trial update reports on the effect of pioglitazone on mitochondrial function in muscle and adipose tissue in adults with Type …
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Exercise and the Receptor for Advanced Glycation End Products (RAGE) [NA]
This clinical trial evaluated the impact of exercise on the receptor for advanced glycation end products (RAGE) in adults with Type 2 diabet…
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CLINICAL_TRIALS trial_result · 2024-08-12Clinical Trial Update: Improving Diabetes Through Lifestyle and Surgery [Phase 2, Phase 3]
This clinical trial update reports completion of a Phase 2/3 study evaluating lifestyle modification and surgical interventions to improve d…
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CLINICAL_TRIALS trial_result · 2024-08-12Clinical Trial Update: Study of Multiple Oral Doses of PF-07081532 in Adult Participants With Type 2 Diabetes Mellitus [Phase 1]
Phase 1 trial of multiple oral doses of PF-07081532 in adults with Type 2 Diabetes Mellitus completed; results have been posted.
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FDA approval · 2024-08-09FDA Approved: REZVOGLAR KWIKPEN — Supplemental Application (Eli Lilly and Company)
The FDA approved a supplemental application for Rezvoglar KwikPen (insulin glargine-AGLR) from Eli Lilly and Company.
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Effect of Novel Glucagon Receptor Antagonist REMD-477 on Glucose and Adipocyte Metabolism in T2DM [EARLY_Phase 1]
An early-phase 1 trial assessing REMD-477, a glucagon receptor antagonist, for effects on glucose and adipocyte metabolism in individuals wi…
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Identification of Fatty Liver With Advanced Fibrosis in Type 2 Diabetes Using Simple Fibrosis Scores and Electronic Reminder Messages [NA]
This completed clinical trial evaluated simple fibrosis scoring methods and electronic reminder messages to identify nonalcoholic fatty live…
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Metabolic Syndrome and Related Diseases in Healthcare Workers
A completed clinical trial evaluated metabolic syndrome and related conditions in healthcare workers. The study encompassed metabolic syndro…
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: A Study to Assess the Safety and Efficacy of Oral Insulin in T2DM Patients With Nonalcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 trial evaluating the safety and efficacy of an oral insulin formulation in adults with type 2 diabetes and nonalcoholic steatohepati…
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: A Study of Efficacy and Safety of Supaglutide in Type 2 Diabetes Patients(SUPER-1) [Phase 2, Phase 3]
A completed Phase 2/3 trial evaluating the efficacy and safety of Supaglutide in adults with Type 2 diabetes mellitus.