Type 1 Diabetes Mellitus
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CLINICAL_TRIALS trial_result · 2017-10-25Clinical Trial Update: Closed-loop Glucose Control for Automated Management of Type 1 Diabetes [NA]
This trial evaluated a closed-loop, automated glucose control system for Type 1 diabetes, and results have been posted following completion.
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CLINICAL_TRIALS trial_result · 2017-10-23Clinical Trial Update: Mini-Dose Glucagon to Treat Non-Severe Hypoglycemia [Phase 2]
A Phase 2 trial studying mini-dose glucagon for treating non-severe hypoglycemia in Type 1 diabetes completed with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-10-20Clinical Trial Update: A Multicenter Study of Outpatient Automated Blood Glucose Control With a Bihormonal Bionic Pancreas [NA]
This record notes the completion and posting of results from a multicenter outpatient study evaluating automated glucose control with a biho…
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CLINICAL_TRIALS trial_result · 2017-10-20Clinical Trial Update: Open-label Investigation of the Safety and Effectiveness of DIABECELL® in Patients With Type 1 Diabetes Mellitus [Phase 1, Phase 2]
Open-label Phase 1/2 trial evaluating safety and effectiveness of DIABECELL in patients with Type 1 diabetes mellitus has completed.
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CLINICAL_TRIALS trial_result · 2017-10-20Clinical Trial Update: Open-label Investigation of the Safety and Effectiveness of DIABECELL(R) in Patients With Type I Diabetes Mellitus [Phase 1, Phase 2]
This is a completed open-label Phase 1/2 trial evaluating the safety and effectiveness of DIABECELL in people with Type 1 diabetes mellitus.
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CLINICAL_TRIALS trial_result · 2017-10-20Clinical Trial Update: Efficacy of Islet After Kidney Transplantation [Phase 3]
Phase 3 trial evaluating islet transplantation after kidney transplantation for Type 1 Diabetes Mellitus has completed, with reported effica…
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CLINICAL_TRIALS trial_result · 2017-10-20Clinical Trial Update: The Summer Camp Study 2: Blood Glucose Control With a Bi-Hormonal Endocrine Pancreas [NA]
The Summer Camp Study 2 trial, evaluating blood glucose control with a bi-hormonal endocrine pancreas for Type 1 Diabetes, has completed and…
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CLINICAL_TRIALS trial_result · 2017-10-20Clinical Trial Update: The Effects of Mediterranean Diet on Remission, Lipid Profile, Weight and Body Composition in Children and Adolescents With Newly Diagnosed Type 1 Diabetes [NA]
The trial evaluating the effects of a Mediterranean diet on remission, lipid profile, weight, and body composition in children and adolescen…
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CLINICAL_TRIALS withdrawal · 2017-10-20Clinical Trial Update: An Exploratory Clinical Trial to Generate Whole Blood Samples for Analysing Genetic Polymorphisms
An exploratory clinical trial to collect whole blood samples for analyzing genetic polymorphisms was withdrawn.
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CLINICAL_TRIALS research · 2017-10-19Clinical Trial Update: Randomized Crossover Study to Test the Impact of Using a Software for Smartphones and Tablets in Treating Type 1 Diabetes [NA]
This entry notes the completion of a randomized crossover trial assessing a smartphone/tablet software tool for managing Type 1 diabetes, in…
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CLINICAL_TRIALS research · 2017-10-19Clinical Trial Update: Continuous Glucose Monitoring During Intecorse in Young Adults With Type 1 Diabetes
A clinical trial update describing continuous glucose monitoring during intercourse in young adults with Type 1 diabetes.
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CLINICAL_TRIALS trial_result · 2017-10-18Clinical Trial Update: Study of Insulin Pump in Prevention of Low Glucose Events in Adults With Type 1 Diabetes at Risk of Severe Hypoglycemia [NA]
A completed clinical trial evaluating the use of an insulin pump to prevent low glucose events in adults with Type 1 diabetes who are at ris…
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CLINICAL_TRIALS trial_result · 2017-10-09Clinical Trial Update: A Study to Assess the Safety of Single Doses of GSK189075 in Subjects With Type 1 Diabetes Mellitus [Phase 2]
Phase 2 safety study update reporting results for a single-dose administration of GSK189075 in adults with Type 1 diabetes mellitus.
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CLINICAL_TRIALS trial_result · 2017-10-09Clinical Trial Update: A Trial Evaluating the Effect of NN1250 at Steady State Conditions in Subjects With Type 1 Diabetes [Phase 1]
A Phase 1 study evaluating NN1250 at steady state in adults with Type 1 diabetes mellitus has completed, reporting results from the trial.
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CLINICAL_TRIALS trial_result · 2017-10-09Clinical Trial Update: A Trial Investigating the Within-subject Variability of NN1250 in Subjects With Type 1 Diabetes [Phase 1]
Phase 1 trial evaluating the within-subject variability of NN1250 in subjects with Type 1 diabetes mellitus has completed.
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CLINICAL_TRIALS trial_result · 2017-10-03Clinical Trial Update: Trial of Otelixizumab for Adults With Newly Diagnosed Type 1 Diabetes Mellitus (Autoimmune): DEFEND-1 [Phase 3]
Phase 3 trial DEFEND-1 evaluating Otelixizumab in adults with newly diagnosed type 1 diabetes completed with posted results.
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FDA approval · 2017-09-29FDA Approved: AFREZZA — Supplemental Application (Mannkind Corporation)
The FDA approved a supplemental application for AFREZZA (insulin human) from Mannkind Corporation.
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FDA approval · 2017-09-29FDA Approved: FIASP — Original Application (Novo Nordisk)
FDA approves the original application for FIASP (insulin aspart injection) by Novo Nordisk.
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CLINICAL_TRIALS trial_result · 2017-09-29Clinical Trial Update: Medtronic Treat to Range (TTR) Closed-Loop Control [NA]
Completed clinical trial update for Medtronic Treat to Range (TTR) closed-loop control in Type 1 diabetes; results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-09-26Clinical Trial Update: Islet Allotransplantation for Type 1 Diabetic Patients [Phase 3]
Phase 3 clinical trial update on islet allotransplantation for patients with type 1 diabetes.
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CLINICAL_TRIALS trial_result · 2017-09-18Clinical Trial Update: Combination Therapy With Sitagliptin and Lansoprazole to Restore Pancreatic Beta Cell Function in Recent-Onset Type 1 Diabetes [Phase 2]
A Phase 2 trial evaluated a combination of sitagliptin and lansoprazole to restore pancreatic beta cell function in recent-onset Type 1 Diab…
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CLINICAL_TRIALS trial_result · 2017-09-15Clinical Trial Update: Trial of Otelixizumab for Adolescents and Adults With Newly Diagnosed Type 1 Diabetes Mellitus (Autoimmune): DEFEND-2 [Phase 3]
Phase 3 trial (DEFEND-2) evaluating otelixizumab in adolescents and adults with newly diagnosed type 1 diabetes completed with posted result…
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CLINICAL_TRIALS trial_result · 2017-09-12Clinical Trial Update: Medtronic MiniMed Implantable Insulin Pump [NA]
Clinical trial update for the Medtronic MiniMed Implantable Insulin Pump study completed; results posted in 2017 for Type 1 Diabetes.
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CLINICAL_TRIALS trial_result · 2017-08-31Clinical Trial Update: Effect of Ethanol Intoxication on the Anti-Hypoglycemic Action of Glucagon [Phase 4]
Phase 4 trial from Massachusetts General Hospital evaluated how ethanol intoxication influences glucagon's anti-hypoglycemic effect in indiv…
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CLINICAL_TRIALS research · 2017-08-29Clinical Trial Update: ECG Changes in Children and Adolescents With Type 1 Diabetes
Assiut University is updating a clinical trial examining ECG changes in children and adolescents with Type 1 diabetes.