Type 1 Diabetes Mellitus
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CLINICAL_TRIALS trial_result · 2010-08-04Clinical Trial Update: Effect of Insulin Detemir on Use of Energy in Type 1 Diabetes [Phase 4]
Phase 4 clinical trial update on insulin detemir in type 1 diabetes; the study was terminated and results were posted in 2010.
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CLINICAL_TRIALS trial_result · 2010-08-03Clinical Trial Update: Carbohydrate Counting in Adults With Type 1 Diabetes Treated With Continuous Subcutaneous Insulin Infusion [Phase 3]
A Phase 3 clinical trial evaluating carbohydrate counting in adults with Type 1 diabetes treated with continuous subcutaneous insulin infusi…
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CLINICAL_TRIALS trial_result · 2010-07-30Clinical Trial Update: Effect of Insulin Glulisine Compared to Insulin Aspart and Insulin Lispro When Administered by Continuous Subcutaneous Insulin Infusion (CSII) on Specific Pump Parameters in Patient With Type 1 Diabetes Mellitus [Phase 4]
A Phase 4 trial evaluated insulin glulisine versus insulin aspart and insulin lispro delivered by continuous subcutaneous insulin infusion i…
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CLINICAL_TRIALS withdrawal · 2010-07-30Clinical Trial Update: Expanding Coverage of Continuous Subcutaneous Insulin Infusion in Pediatric Patients With Diabetes [NA]
A pediatric trial evaluating expanded coverage for continuous subcutaneous insulin infusion in Type 1 diabetes has been withdrawn. The spons…
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CLINICAL_TRIALS trial_result · 2010-07-22Clinical Trial Update: Noninvasive Transcutaneous Glucometer Development
The document reports the completion of a clinical trial evaluating a noninvasive transcutaneous glucometer. The study enrolled healthy parti…
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CLINICAL_TRIALS trial_result · 2010-07-09Clinical Trial Update: Islet Cell Transplantation Alone in Patients With Type I Diabetes Mellitus: Steroid-free Immunosuppression [Phase 2]
Phase 2 trial evaluating islet cell transplantation with steroid-free immunosuppression in type 1 diabetes mellitus has completed.
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CLINICAL_TRIALS research · 2010-06-14Clinical Trial Update: Stem Cell Therapy for Type 1 Diabetes Mellitus [Phase 1]
This entry reports a Phase 1 clinical trial of a stem cell therapy from Cellonis Biotechnology Co. Ltd. for Type 1 Diabetes Mellitus. The cu…
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FDA approval · 2010-06-10FDA Approved: HUMULIN N — Supplemental Application (Eli Lilly and Company)
The FDA approved a supplemental application for HUMULIN N (insulin human) filed by Eli Lilly and Company.
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CLINICAL_TRIALS other · 2010-06-02Clinical Trial Update: Pancreas Allotransplantation for Diabetic Nephropathy and Mild Chronic REnal fAilure Stage Study [Phase 3]
Clinical trial update for a Phase 3 study of pancreas allotransplantation in type 1 diabetes patients with diabetic nephropathy and mild chr…
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CLINICAL_TRIALS withdrawal · 2010-05-31Clinical Trial Update: Transplantation of Pancreatic Islets in Patients With Type 1 Diabetes Mellitus and Functional Kidney Graft [Phase 1, Phase 2]
Phase 1/2 trial investigating pancreatic islet transplantation in Type 1 Diabetes Mellitus patients with a functional kidney graft has been …
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CLINICAL_TRIALS trial_result · 2010-05-12Clinical Trial Update: Islet Allotransplantation With Steroid Free Immunosuppression [Phase 2]
Phase 2 trial evaluating islet allotransplantation with steroid-free immunosuppression in Type 1 diabetes. Results posted in 2010 report gly…
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CLINICAL_TRIALS research · 2010-05-12Clinical Trial Update: Closing the Loop in Adults With Type 1 Diabetes - Alcohol Consumption [NA]
A completed clinical trial update examining the effects of alcohol consumption in adults with Type 1 diabetes mellitus.
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CLINICAL_TRIALS trial_result · 2010-05-10Clinical Trial Update: Efficacy of Calcitriol in Recent Onset Type 1 Diabetes [Phase 2]
A Phase 2 trial evaluating calcitriol for efficacy in recent-onset Type 1 diabetes mellitus has completed.
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CLINICAL_TRIALS trial_result · 2010-05-04Clinical Trial Update: BABYDIET-Study - Primary Prevention of Type 1 Diabetes in Relatives at Increased Genetic Risk [NA]
The BABYDIET study is a clinical trial evaluating primary prevention of Type 1 diabetes in relatives at increased genetic risk, with the cur…
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CLINICAL_TRIALS trial_result · 2010-04-15Clinical Trial Update: Efficacy of Continuous Glucose Monitoring in Subjects With Type 1 Diabetes Mellitus on Multiple Daily Injections (MDI) or Continuous Subcutaneous Insulin Infusion (CSII) Therapy
A completed study evaluating the efficacy of continuous glucose monitoring (CGM) in people with Type 1 diabetes treated with multiple daily …
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CLINICAL_TRIALS trial_result · 2010-03-30Clinical Trial Update: Assessing Glucose Effects of Sitagliptin (Januvia) in Adult Patients With Type 1 Diabetes [Phase 4]
This Phase 4 clinical trial update reports on the effects of sitagliptin (Januvia) on glucose in adults with Type 1 diabetes. The study stat…
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CLINICAL_TRIALS research · 2010-03-17Clinical Trial Update: Joint Application of Human Insulin and Rapid Insulin Analogue in Control of Postprandial Glycemia [NA]
This clinical trial investigates using a combination of human insulin and a rapid-acting insulin analogue to control postprandial blood gluc…
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CLINICAL_TRIALS trial_result · 2010-03-11Clinical Trial Update: Reinforcement of the Impact of a Functional Insulin Therapy Training Course by Telemonotoring With a PDA-phone in Type 1 Diabetic Patients. The TELFIT Study Patients [Phase 3]
Phase 3 TELFIT study assessing reinforcement of functional insulin therapy training via telemonitoring with a PDA-phone in Type 1 Diabetes h…
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CLINICAL_TRIALS trial_result · 2010-03-10Clinical Trial Update: Pharmacokinetics/Dynamics of Basal (Continuous) Insulin Infusion Administered Either Intradermally or Subcutaneously [Phase 1, Phase 2]
A Phase 1/2 trial assessing the pharmacokinetics and pharmacodynamics of basal continuous insulin infusion delivered intradermally or subcut…
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CLINICAL_TRIALS trial_result · 2010-03-10Clinical Trial Update: Evaluation of Blood Volume and Perceived Pain During Fingerstick Monitoring of Blood Glucose [NA]
The update reports results from a completed study evaluating blood volume and pain during fingerstick glucose monitoring in people with diab…
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CLINICAL_TRIALS trial_result · 2010-03-05Clinical Trial Update: Gene Expression Profiling in Type 1 Diabetes
A completed clinical trial investigating gene expression profiling in individuals with Type 1 Diabetes Mellitus.
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CLINICAL_TRIALS trial_result · 2010-03-05Clinical Trial Update: Molecular Quantification of Insulin mRNA
Completed clinical trial at Children's Mercy Hospital Kansas City investigating molecular quantification of insulin mRNA in Type 1 Diabetes …
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CLINICAL_TRIALS trial_result · 2010-03-02Clinical Trial Update: Diabetes Control and Complications Trial (DCCT) [NA]
Update on the Diabetes Control and Complications Trial (DCCT), a pivotal study comparing intensive insulin therapy with conventional treatme…
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CLINICAL_TRIALS trial_result · 2010-03-02Clinical Trial Update: Islet Cell Transplantation Alone and CD34+ Enriched Bone Marrow Cell Infusion in Patients With Diabetes Mellitus: Steroid-Free Regimen [Phase 2]
A Phase 2 trial evaluating a steroid-free regimen combining islet cell transplantation with CD34+ enriched bone marrow cell infusion in Type…
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CLINICAL_TRIALS trial_result · 2010-03-02Clinical Trial Update: Breaking Down Barriers to Diabetes Self-Care [NA]
An NIDDK-sponsored clinical trial focused on breaking down barriers to diabetes self-care has completed. The study enrolled individuals with…