Type 1 Diabetes Mellitus
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CLINICAL_TRIALS research · 2014-08-08Clinical Trial Update: Diabetes Intervention Program for Adolescents With Persistent High HA1c [NA]
This update describes a clinical trial evaluating a diabetes intervention program for adolescents with Type 1 diabetes who have persistent h…
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CLINICAL_TRIALS trial_result · 2014-08-04Clinical Trial Update: Post-exercise Insulin Reductions in Type 1 Diabetes [NA]
Completed clinical trial examining how exercise influences insulin requirements in people with Type 1 diabetes.
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CLINICAL_TRIALS trial_result · 2014-08-04Clinical Trial Update: Post-exercise Appetite Responses in Type 1 Diabetes [NA]
This clinical trial update reports completion of a study examining post-exercise appetite responses in individuals with Type 1 Diabetes.
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CLINICAL_TRIALS research · 2014-07-30Clinical Trial Update: Incidence of Retinopathy and Associated Risk Factors in Children and Young Adults With Type 1 Diabetes in Denmark
An update on a Danish observational trial evaluating the incidence of diabetic retinopathy and related risk factors in children and young ad…
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CLINICAL_TRIALS trial_result · 2014-07-29Clinical Trial Update: Subcutaneous Administration of Lisofylline to Healthy Normal Subjects and Subjects With Type 1 Diabetes [Phase 1, Phase 2]
A Phase 1/2 clinical trial update describing subcutaneous lisofylline in healthy subjects and in individuals with Type 1 diabetes, which has…
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CLINICAL_TRIALS trial_result · 2014-07-25Clinical Trial Update: Randomized, Double-blind, Crossover, Pharmacokinetic (PK) and Glucodynamic (GD) Study of Continuous Subcutaneous Insulin Infusion (CSII) in Participants With Type 1 Diabetes Mellitus (T1DM) [Phase 1]
Phase 1 randomized, double-blind, crossover PK and glucodynamic study evaluating continuous subcutaneous insulin infusion in participants wi…
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CLINICAL_TRIALS trial_result · 2014-07-21Clinical Trial Update: A Pilot Study of Moderate Hyperbilirubinemia in Type 1 Diabetes Mellitus [Phase 1]
Phase 1 pilot study evaluating moderate hyperbilirubinemia in Type 1 Diabetes Mellitus. Results have been posted.
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CLINICAL_TRIALS trial_result · 2014-07-11Clinical Trial Update: Safety and Efficacy of INGAP-Peptide in Patients With Type 1 Diabetes [Phase 2]
This Clinical Trial Update reports completion of a Phase 2 study evaluating the safety and efficacy of INGAP-Peptide in patients with Type 1…
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CLINICAL_TRIALS trial_result · 2014-07-04Clinical Trial Update: Closed-loop Control of Glucose Levels (Artificial Pancreas) for 24 Hours in Adults and Adolescents With Type 1 Diabetes [Phase 2]
Phase 2 trial assessing 24-hour closed-loop insulin delivery (artificial pancreas) in adults and adolescents with type 1 diabetes has comple…
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CLINICAL_TRIALS trial_result · 2014-07-03Clinical Trial Update: Efficacy and Safety of Liraglutide in Subjects With Type 1 Diabetes Undergoing Islet Cell Transplantation [Phase 2]
Phase 2 trial results evaluate the efficacy and safety of liraglutide in subjects with Type 1 diabetes undergoing islet cell transplantation…
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FDA approval · 2014-06-27FDA Approved: AFREZZA — Original Application (Mannkind Corporation)
FDA approved AFREZZA (insulin human) from Mannkind Corporation as an original application, introducing an inhaled insulin product for adults…
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CLINICAL_TRIALS trial_result · 2014-06-27Clinical Trial Update: Comparison of Glycemic Control in Obese Diabetics Using Three Different Pen Needles [NA]
A completed clinical trial comparing three different insulin pen needles for glycemic control in obese individuals with type 1 or type 2 dia…
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CLINICAL_TRIALS trial_result · 2014-06-24Clinical Trial Update: A Survey to Evaluate Diabetes Management, Control, Chronic Complications, Psychosocial Aspects of Diabetic Subjects in Indonesia
A completed clinical trial update describes a survey evaluating diabetes management, glycemic control, chronic complications, and psychosoci…
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FDA approval · 2014-06-20FDA Approved: HUMULIN R — Supplemental Application (Eli Lilly and Company)
The FDA approved a supplemental application for HUMULIN R (insulin human) from Eli Lilly and Company.
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CLINICAL_TRIALS trial_result · 2014-06-19Clinical Trial Update: Investigation of Pain During Subcutaneous Injections With Different Injection Speed and Volume Combinations [Phase 1]
Phase 1 study evaluating pain during subcutaneous injections with varying injection speeds and volumes in diabetes patients; results have be…
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CLINICAL_TRIALS trial_result · 2014-06-19Clinical Trial Update: Feasibility Study of a Portable Artificial Pancreas System in Type 1 Diabetes Mellitus (T1DM) - Padova [EARLY_Phase 1]
A Phase 1 feasibility study in Padova evaluated a portable artificial pancreas system for Type 1 diabetes mellitus, and the trial has comple…
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CLINICAL_TRIALS trial_result · 2014-06-17Clinical Trial Update: Safety and Efficacy of Empagliflozin (BI 10773) in Type 1 Diabetes Mellitus Patients With or Without Renal Hyperfiltration [Phase 2]
A Phase 2 trial evaluating the safety and efficacy of empagliflozin in patients with Type 1 diabetes, with or without renal hyperfiltration.…
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CLINICAL_TRIALS trial_result · 2014-06-16Clinical Trial Update: Comparing Insulin Aspart With Fast-acting Insulin Human in Subjects With Type 1 Diabetes [Phase 1]
Phase 1 clinical trial comparing insulin aspart with regular human insulin in individuals with Type 1 diabetes. The study aims to assess pha…
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CLINICAL_TRIALS withdrawal · 2014-06-12Clinical Trial Update: Safety and Effectiveness of Low Molecular Weight Sulfated Dextran in Islet Transplantation After Kidney Transplant [Phase 2]
A Phase 2 trial evaluating the safety and effectiveness of Low Molecular Weight Sulfated Dextran in islet transplantation after kidney trans…
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CLINICAL_TRIALS trial_result · 2014-06-11Clinical Trial Update: PST Linkage Based Analysis in the Family of More Than Two Members With Type 1 Diabetes in Taiwan
A completed clinical trial from Chang Gung Memorial Hospital evaluating PST linkage-based analysis of genetic variation in families with Typ…
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CLINICAL_TRIALS trial_result · 2014-06-11Clinical Trial Update: B-Lymphocyte Immunotherapy in Islet Transplantation for Initial Islet Graft Failure
This clinical trial update concerns a NIAID-sponsored study of B-lymphocyte immunotherapy in islet transplantation for initial islet graft f…
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FDA approval · 2014-06-10FDA Approved: HUMULIN N — Supplemental Application (Eli Lilly and Company)
FDA approves a supplemental application for Humulin N (insulin human) submitted by Eli Lilly and Company. This action is an approval of a su…
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CLINICAL_TRIALS trial_result · 2014-06-09Clinical Trial Update: Comparison of a New Formulation of Insulin Glargine With Lantus® in Japanese Patients With Type 1 Diabetes Mellitus [Phase 3]
Phase 3 trial comparing a new formulation of insulin glargine with Lantus in Japanese patients with Type 1 diabetes mellitus; study complete…
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CLINICAL_TRIALS trial_result · 2014-06-06Clinical Trial Update: Pancreatic Islet Cell Transplantation [Phase 1]
Phase 1 trial results evaluating pancreatic islet cell transplantation for Type 1 diabetes were reported. The update summarizes the safety a…
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CLINICAL_TRIALS trial_result · 2014-06-05Clinical Trial Update: Outpatient Pump Shutoff Pilot Feasibility and Efficacy Study [Phase 2]
Phase 2 trial evaluating feasibility and efficacy of an outpatient insulin pump shutoff strategy in Type 1 diabetes. The study is completed …