Type 1 Diabetes Mellitus
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CLINICAL_TRIALS withdrawal · 2026-03-24Clinical Trial Update: Clinican BEAD-T1D: Building the Evidence to Address Disengagement in Type 1 Diabetes [NA]
The Clinican BEAD-T1D trial at Stanford University building evidence to address disengagement in Type 1 diabetes has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2026-03-02Clinical Trial Update: Slow Digestible Carbohydrates and Exercise in Adolescents With Type 1 Diabetes [NA]
Clinical trial evaluating slow-digestible carbohydrates as an adjunct to exercise in adolescents with type 1 diabetes; the study has been wi…
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CLINICAL_TRIALS withdrawal · 2026-02-12Clinical Trial Update: Effectiveness of Nutrition Education in Carbohydrate Counting in People With Type 1 Diabetic [NA]
A clinical trial evaluating nutrition education for carbohydrate counting in people with Type 1 diabetes has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2026-02-11Clinical Trial Update: Siplizumab in T1DM [Phase 1, Phase 2]
A Phase 1/2 trial of siplizumab for Type 1 diabetes mellitus was terminated.
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CLINICAL_TRIALS withdrawal · 2026-01-15Clinical Trial Update: Diabetes Islet Preservation Immune Treatment [Phase 1, Phase 2]
The clinical trial on Diabetes Islet Preservation Immune Treatment (Phase 1/2) has been withdrawn. It targeted type 1 diabetes and related h…
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CLINICAL_TRIALS withdrawal · 2025-11-10Clinical Trial Update: Glucagon-like Peptide-1 in Type 1 Diabetes [EARLY_Phase 1]
An early Phase 1 trial evaluating a glucagon-like peptide-1 therapy for Type 1 diabetes mellitus was withdrawn, sponsored by the University …
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CLINICAL_TRIALS withdrawal · 2025-10-16Clinical Trial Update: A Study of the Safety and Efficacy of Pancreatic Endocrine Cell Clusters Implanted Into the Omentum of Type 1 Diabetes Patients With Severe Hypoglycemia [Phase 1, Phase 2]
A Phase 1/2 study evaluating pancreatic endocrine cell clusters implanted into the omentum for Type 1 diabetes patients with severe hypoglyc…
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CLINICAL_TRIALS withdrawal · 2025-10-09Clinical Trial Update: Technology Knowledge Optimization in Type 1 Diabetes (TeKnO T1D): Parents [NA]
The TeKnO T1D: Parents trial has been withdrawn. The sponsor is Children's Hospital of Philadelphia.
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CLINICAL_TRIALS withdrawal · 2025-09-25Clinical Trial Update: STOP-T1D Low-Dose (ATG) [Phase 2]
The STOP-T1D Low-Dose ATG Phase 2 trial for type 1 diabetes mellitus has been terminated.
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CLINICAL_TRIALS withdrawal · 2025-09-03Clinical Trial Update: Pancreatic Islet Transplantation to the Anterior Chamber of the Eye [NA]
Clinical trial investigating pancreatic islet transplantation to the anterior chamber of the eye for Type 1 diabetes mellitus with visual im…
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CLINICAL_TRIALS withdrawal · 2025-06-17Clinical Trial Update: cePolyTregs in Islet Transplantation [Phase 1]
A Phase 1 trial of cePolyTregs for islet transplantation in type 1 diabetes has been withdrawn. Sponsor is the University of Alberta.
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CLINICAL_TRIALS withdrawal · 2025-06-03Clinical Trial Update: SYNERGY PLUS: Evaluation of Next Generation Sensors (NGS) and Algorithm in Patients With Type 1 and Type 2 Diabetes [NA]
A clinical trial evaluating next-generation sensors and algorithms for diabetes management has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-12-09Clinical Trial Update: Study to Explore the Effect of Dapagliflozin and Stress in Adolescent and Adult Subjects With Type 1 Diabetes (T1D) [Phase 1]
A Phase 1 trial evaluating dapagliflozin in adolescents and adults with Type 1 diabetes was terminated. The study also included subjects wit…
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CLINICAL_TRIALS withdrawal · 2024-05-22Clinical Trial Update: Low-dose IL-2 in Established T1D - The "PROREG" Study [Phase 1, Phase 2]
A Phase 1/2 trial evaluating low-dose interleukin-2 in established type 1 diabetes has been withdrawn from ClinicalTrials.gov.
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CLINICAL_TRIALS withdrawal · 2023-03-23Clinical Trial Update: Empagliflozin in Adolescent Diabetes [Phase 4]
Phase 4 trial of empagliflozin in adolescents with type 1 diabetes was withdrawn.
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EMA withdrawal · 2022-08-16EMA Withdrawn: Zynquista (sotagliflozin) — Guidehouse Germany GmbH
The EMA withdrew Zynquista (sotagliflozin) from development/marketing for Type 1 diabetes, with Guidehouse Germany GmbH as the MAH, decision…
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CLINICAL_TRIALS withdrawal · 2020-02-05Clinical Trial Update: Gan & Lee Evaluation of New Biosimilar for Type 1 Lispro [Phase 3]
Phase 3 trial evaluating a new lispro biosimilar for type 1 diabetes was withdrawn.
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CLINICAL_TRIALS withdrawal · 2019-10-08Clinical Trial Update: Immunogenicity Safety Study of Wockhardt's Recombinant Insulin Analogue in Type 1 Diabetic Patients [Phase 3]
A Phase 3 immunogenicity and safety study of Wockhardt's recombinant insulin analogue in Type 1 diabetes has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2019-02-15Clinical Trial Update: Vitamin C and Liraglutide Effects on Hypoglycemia-induced Oxidative Stress, Inflammation and Endothelial Dysfunction in Type 1 Diabetes. [Phase 1]
A Phase 1 trial evaluating vitamin C and liraglutide for hypoglycemia-related oxidative stress, inflammation, and endothelial dysfunction in…
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CLINICAL_TRIALS withdrawal · 2019-01-08Clinical Trial Update: Efficacy of Pramlintide on Prevention of Weight Gain Early Onset of Type 1 Diabetes [Phase 4]
A Phase 4 clinical trial evaluating pramlintide to prevent weight gain in early onset Type 1 Diabetes was withdrawn.
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CLINICAL_TRIALS withdrawal · 2018-05-16Clinical Trial Update: Glucotoxicity and Acute Exercise [NA]
The clinical trial NCT01771614 on glucotoxicity and acute exercise in individuals with diabetes has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2018-05-11Clinical Trial Update: Gene-virus Interactions Implicated in Type 1 Diabetes [NA]
A clinical trial investigating gene-virus interactions in Type 1 diabetes has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2018-04-27Clinical Trial Update: Comparison of the Efficacy of Rapid-acting Aspart and Faster Acting Aspart Within the Context of Single-hormone Closed-loop Strategy at Regulating Postprandial Glucose Levels [Phase 2]
A Phase 2 trial comparing rapid-acting insulin aspart versus faster-acting aspart within a single-hormone closed-loop system for regulating …
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CLINICAL_TRIALS withdrawal · 2018-04-18Clinical Trial Update: Role of Pregnancy Related Hormones in Lowering the Insulin Requirement in Pregnant Women With Type 1 Diabetes [Phase 1]
Phase 1 clinical trial evaluating whether pregnancy-related hormones can reduce insulin requirements in pregnant women with Type 1 diabetes;…
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CLINICAL_TRIALS withdrawal · 2018-03-15Clinical Trial Update: Safety and Efficacy Study of Encapsulated Human Islets Allotransplantation to Treat Type 1 Diabetes [Phase 1]
A Phase 1 safety and efficacy trial of encapsulated human islets allotransplantation for type 1 diabetes was withdrawn prior to completion.