Tuberous Sclerosis Complex
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-08-25Clinical Trial Update: Safety of Simvastatin in LAM and TSC [Phase 1, Phase 2]
A Phase 1/2 trial reported on the safety of simvastatin in patients with Lymphangioleiomyomatosis and Tuberous Sclerosis Complex; study comp…
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CLINICAL_TRIALS trial_result · 2020-06-09Clinical Trial Update: Aspirin as an add-on Treatment of Refractory Epilepsy in Tuberous Sclerosis Complex [Phase 2]
A Phase 2 clinical trial investigates aspirin as an add-on treatment for refractory epilepsy in tuberous sclerosis complex.
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CLINICAL_TRIALS trial_result · 2018-11-07Clinical Trial Update: A Placebo-controlled Study of Efficacy & Safety of 2 Trough-ranges of Everolimus as Adjunctive Therapy in Patients With Tuberous Sclerosis Complex (TSC) & Refractory Partial-onset Seizures [Phase 3]
Phase 3 trial evaluating efficacy and safety of two trough ranges of everolimus as adjunctive therapy in tuberous sclerosis complex–associat…
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CLINICAL_TRIALS trial_result · 2018-05-02Clinical Trial Update: Early Behavioral Intervention to Improve Social Communication Function in Infants With Tuberous Sclerosis Complex [NA]
This is an update on a completed clinical trial evaluating early behavioral intervention to improve social communication in infants with tub…
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CLINICAL_TRIALS trial_result · 2018-01-25Clinical Trial Update: Trial of RAD001 and Neurocognition in Tuberous Sclerosis Complex (TSC) [Phase 2]
Phase 2 trial update for RAD001 in tuberous sclerosis complex evaluating neurocognition; study completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-01-23Clinical Trial Update: Treatment of Renal Angiomyolipomas in Tuberous Sclerosis by Beta-blockers [Phase 2]
Phase 2 trial evaluating beta-blockers for treatment of renal angiomyolipomas in tuberous sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2017-05-04Clinical Trial Update: Topical Rapamycin and Calcitriol for Angiofibroma of Tuberous Sclerosis [Phase 3]
Phase 3 trial evaluating topical rapamycin combined with calcitriol for facial angiofibromas in tuberous sclerosis complex has completed.
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CLINICAL_TRIALS trial_result · 2017-02-02Clinical Trial Update: Phase III Trial of Topical Formulation of Sirolimus to Skin Lesions in Patients With Tuberous Sclerosis Complex (TSC) [Phase 3]
Phase 3 trial evaluating topical sirolimus for skin lesions in tuberous sclerosis complex has completed.
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CLINICAL_TRIALS trial_result · 2016-09-23Clinical Trial Update: Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC) [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluated everolimus for epilepsy in patients with tuberous sclerosis complex; results were posted in 2…
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CLINICAL_TRIALS trial_result · 2016-08-19Clinical Trial Update: Tuberous Sclerosis Complex: Facial Angiofibroma Skin Cream [Phase 1]
Phase 1 trial of a facial angiofibroma skin cream for tuberous sclerosis complex has completed.
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CLINICAL_TRIALS trial_result · 2015-12-02Clinical Trial Update: Doxycycline In Lymphangioleiomyomatosis (LAM) [Phase 4]
Phase 4 trial of doxycycline in lymphangioleiomyomatosis (LAM) has been completed, including cases associated with tuberous sclerosis comple…
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CLINICAL_TRIALS trial_result · 2015-05-07Clinical Trial Update: The Cognitive Variability in NF1 and TSC Monozygotic Twins
Clinical trial update examining cognitive variability in monozygotic twins with Neurofibromatosis Type I and Tuberous Sclerosis Complex.
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CLINICAL_TRIALS trial_result · 2015-05-05Clinical Trial Update: Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis Complex [Phase 2, Phase 3]
Phase 2/Phase 3 clinical trial evaluating the efficacy of everolimus (RAD001) for autism spectrum disorders and neuropsychological deficits …
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CLINICAL_TRIALS trial_result · 2014-10-20Clinical Trial Update: Everolimus (RAD001) Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis Complex [Phase 1, Phase 2]
This clinical trial update reports results for everolimus (RAD001) therapy of giant cell astrocytoma in patients with tuberous sclerosis com…
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CLINICAL_TRIALS trial_result · 2013-09-25Clinical Trial Update: RAD001 Therapy of Angiomyolipomata in Patients With TS Complex and Sporadic LAM [Phase 1, Phase 2]
A Phase 1/2 trial evaluated the mTOR inhibitor everolimus (RAD001) for angiomyolipomata in patients with tuberous sclerosis complex and spor…
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CLINICAL_TRIALS trial_result · 2013-09-18Clinical Trial Update: Long Term Follow Up for RAD001 Therapy of Angiomyolipomata in Patients With Tuberous Sclerosis (TSC) and Sporadic Lymphangioleiomyomatosis (LAM) [Phase 1, Phase 2]
Long-term follow-up results for everolimus (RAD001) therapy in patients with tuberous sclerosis complex-associated angiomyolipoma and sporad…
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CLINICAL_TRIALS trial_result · 2012-08-28Clinical Trial Update: Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM) [Phase 3]
Phase 3 trial assessing the efficacy and safety of everolimus (RAD001) in adults with angiomyolipoma associated with tuberous sclerosis comp…
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CLINICAL_TRIALS trial_result · 2012-03-08Clinical Trial Update: Rapamycin In Angiomyolipomas In Patients With Tuberous Sclerosis [Phase 4]
Phase 4 clinical trial update on rapamycin (sirolimus) for angiomyolipomas in patients with tuberous sclerosis; the study has completed.
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CLINICAL_TRIALS trial_result · 2012-02-27Clinical Trial Update: Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1) [Phase 1]
Phase 1 trial evaluating topical rapamycin for cutaneous manifestations of tuberous sclerosis complex and neurofibromatosis type 1 has compl…
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CLINICAL_TRIALS trial_result · 2008-04-30Clinical Trial Update: Trial of Efficacy and Safety of Sirolimus in Tuberous Sclerosis and LAM [Phase 2]
Phase 2 trial evaluating the efficacy and safety of sirolimus in tuberous sclerosis complex and lymphangioleiomyomatosis.
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CLINICAL_TRIALS trial_result · 2007-04-09Clinical Trial Update: Rapamycin Therapy for Patients With Tuberous Sclerosis Complex and Sporadic LAM [Phase 2]
Phase 2 clinical trial update reports on rapamycin therapy for patients with tuberous sclerosis complex and sporadic lymphangioleiomyomatosi…