Triple-negative Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: TIL-Driven De-escalated Chemotherapy in Stage I-II TNBC [Phase 2]
Phase 2 clinical trial evaluating tumor-infiltrating lymphocyte–driven de-escalation of chemotherapy for Stage I-II triple-negative breast c…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01) [Phase 2, Phase 3]
A Phase 2/3 clinical trial update comparing Izalontamab Brengitecan with standard chemotherapy in previously untreated, locally advanced, re…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Personalized Dendritic Cell Vaccine Pilot for High Risk TNBC After Neoadjuvant Therapy [EARLY_Phase 1]
A personalized dendritic cell vaccine is being evaluated in an early-phase trial for high-risk triple-negative breast cancer after neoadjuva…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Bicalutamide and Abemaciclib in Inoperable or Metastatic Androgen Receptor-positive Triple-negative Breast Cancer [Phase 2]
Phase 2 clinical trial evaluating the combination of bicalutamide and abemaciclib for androgen receptor–positive triple-negative breast canc…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Biolosion Combined Standard Neoadjuvant Therapy to Treat Triple-negative Breast Cancer [Phase 2]
An update on a Phase 2 clinical trial evaluating Biolosion in combination with standard neoadjuvant therapy for triple-negative breast cance…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types [Phase 1]
IDEAYA Biosciences is conducting a Phase 1 study of IDE034 in adults with multiple locally advanced or metastatic solid tumors; the trial is…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer [Phase 3]
Phase III study evaluating Dato-DXd with or without durvalumab vs investigator's choice of chemotherapy in combination with pembrolizumab fo…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers [Phase 1]
Phase 1 study of AB598 as monotherapy and in combination across multiple advanced cancers is ongoing, with status active but not recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Breast Cancer PSMA PET [EARLY_Phase 1]
Early Phase 1 clinical trial investigating PSMA PET imaging in triple-negative breast cancer is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Gut and Intratumoral Microbiome Effect on the Neoadjuvant Chemotherapy-induced Immunosurveillance in Triple Negative Breast Cancer
A completed study investigating the impact of gut and intratumoral microbiomes on chemo-induced immune responses in patients with triple-neg…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: 177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors [Phase 1, Phase 2]
This clinical trial update describes ongoing Phase 1/2 studies of the radiopharmaceutical 177Lu-BetaBart. The trial is evaluating its use in…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Deployment and Clinical Evaluation of an AI-powered Digital Oncology Biomarker Tool to guidE Treatment in TNBC
A clinical trial update describing deployment and clinical evaluation of an AI-powered digital oncology biomarker tool to guide treatment in…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: BAL0891 in Patients With Advanced Solid Tumors or Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
This clinical trial update notes a Phase 1 study of BAL0891 by SillaJen in patients with advanced solid tumors, including triple-negative br…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Exemption of SLNB After Neoadjuvant Therapy for Triple-negative and Her2-positive Breast Cancer [NA]
A clinical trial is evaluating whether sentinel lymph node biopsy can be omitted after neoadjuvant therapy in patients with triple-negative …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Peri-Operative Immune Checkpoint Inhibition and Cryoablation in Women With Triple-negative Breast Cancer [Phase 2]
Phase 2 clinical trial evaluating peri-operative immune checkpoint inhibition with cryoablation in women with triple-negative breast cancer;…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Precise Treatment for BLIS Subtype of TNBC in the First-line Treatment of Locally Advanced or Metastatic Breast Cancer [Phase 3]
Phase 3 trial evaluating a BLIS subtype-specific treatment for first-line locally advanced or metastatic triple-negative breast cancer is cu…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: A Single-Arm, Single-Center, Phase II Clinical Study of Camrelizumab Combined With Radiochemotherapy as Neoadjuvant Therapy for Early-Stage Triple-Negative Breast Cancer [NA]
Phase II single-arm study evaluating camrelizumab in combination with radiochemotherapy as neoadjuvant therapy for early-stage triple-negati…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4 [Phase 1]
Phase 1/1b trial evaluating RNDO-564 as a single agent or in combination with pembrolizumab in bladder cancer and nectin-4–associated solid …
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Phase II Study of HLX43 Monotherapy or Combined With Immune Checkpoint Inhibitors in Patients With Locally Advanced, Recurrent, or Metastatic Triple-negative Breast Cancer. [Phase 2]
Phase II study evaluating HLX43 alone or in combination with immune checkpoint inhibitors for locally advanced, recurrent, or metastatic tri…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Correlation Between TILs and Blood Cell Counts in Triple Negative Breast Cancer Patients
The clinical trial investigates the relationship between tumor-infiltrating lymphocytes and blood cell counts in patients with triple-negati…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Dual-Target CAR-NK Cells for Advanced Breast Cancer (HER2+ and TNBC) [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating dual-target CAR-NK cells designed to treat HER2-positive and triple-negative breast cancers, with t…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: LifEStyle Intervention to Enhance Efficacy of Neoadjuvant Therapy in Patients With Triple Negative Breast Cancer [Phase 2]
Phase 2 clinical trial investigating LifEStyle lifestyle intervention to enhance efficacy of neoadjuvant therapy in patients with early-stag…
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CLINICAL_TRIALS other · 2026-03-20Clinical Trial Update: Pembrolizumab Adjuvant in Patients With Early-stage Triple Negative Breast Cancer With Residual Disease After Neoadjuvant Pembrolizumab Plus Chemotherapy [Phase 3]
This Phase 3 trial evaluates pembrolizumab as adjuvant therapy in patients with early-stage triple-negative breast cancer who have residual …
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Metabolic Flexibility in Patients With Early Triple-negative Breast Cancer [NA]
This clinical trial update describes a study on metabolic flexibility in patients with early triple-negative breast cancer, which is current…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Neoadjuvant Study of HIFU With or Without PD-1 Inhibitors Followed by Abraxane Plus Carboplatin in Triple-Negative Breast Cancer. [Phase 2]
A Phase 2 neoadjuvant trial evaluating high-intensity focused ultrasound (HIFU) with or without PD-1 inhibitors, followed by Abraxane (nab-p…