Triple-negative Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2014-12-19Clinical Trial Update: Safety and Efficacy Study of Vintafolide and Vintafolide Plus Paclitaxel Compared to Paclitaxel Alone in Participants With Triple Negative Breast Cancer (TNBC) (MK-8109-004) [Phase 2]
Phase 2 safety and efficacy trial of vintafolide (EC145) with or without paclitaxel versus paclitaxel alone in triple-negative breast cancer…
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CLINICAL_TRIALS trial_result · 2014-12-17Clinical Trial Update: Neoadjuvant Sunitinib With Paclitaxel/Carboplatin in Patients With Triple-Negative Breast Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating neoadjuvant sunitinib combined with paclitaxel and carboplatin in patients with triple-negative breast cancer com…
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CLINICAL_TRIALS trial_result · 2014-12-15Clinical Trial Update: Panitumumab, Gemcitabine and Carboplatin in Triple-Negative Metastatic Breast Cancer [Phase 2]
Phase 2 trial evaluating panitumumab with gemcitabine and carboplatin in metastatic triple-negative breast cancer; the study has been comple…
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CLINICAL_TRIALS trial_result · 2014-12-15Clinical Trial Update: Study Of Abraxane® And Carboplatin As First-Line Treatment For Triple Negative Metastatic Breast Cancer [Phase 2]
Phase 2 trial evaluating Abraxane plus carboplatin as first-line therapy for triple-negative metastatic breast cancer was terminated; result…
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CLINICAL_TRIALS trial_result · 2014-12-02Clinical Trial Update: Additional 4 Cycles of Cisplatin (CDDP4) in Patients With Triple Negative Breast Cancer for Neoadjuvant Chemotherapy [Phase 2]
A Phase 2 trial update exploring the addition of four cycles of cisplatin (CDDP4) as neoadjuvant chemotherapy for patients with triple-negat…
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CLINICAL_TRIALS trial_result · 2014-11-13Clinical Trial Update: Study of NK012 and Carboplatin in Solid Tumors With Dose Expansion in Triple Negative Breast Cancer [Phase 1]
Phase 1 study of NK012 in combination with carboplatin in advanced solid tumors with dose expansion in metastatic triple-negative breast can…
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CLINICAL_TRIALS research · 2014-11-13Clinical Trial Update: Metronomic Chemotherapy of Capecitabine After Standard Adjuvant Chemotherapy in Operable Triple Negative Breast Cancer
This document reports on a clinical trial evaluating metronomic capecitabine after standard adjuvant chemotherapy in operable triple-negativ…
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CLINICAL_TRIALS trial_result · 2014-11-05Clinical Trial Update: Induction Preoperative Chemotherapy for Patients With Locally Advanced Triple Negative Breast Cancer [Phase 2]
Phase 2 clinical trial evaluating induction preoperative chemotherapy for locally advanced triple-negative breast cancer has completed.
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CLINICAL_TRIALS trial_result · 2014-09-04Clinical Trial Update: A Clinical Trial Comparing Gemcitabine and Carboplatin With and Without P276-00 in Subjects With Metastatic Triple Negative Breast Cancer, With a Run-in of Escalating Dose of P276-00 Added to Gemcitabine and Carboplatin [Phase 1]
A Phase 1 trial comparing gemcitabine and carboplatin with or without the investigational agent P276-00 in metastatic triple-negative breast…
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CLINICAL_TRIALS trial_result · 2014-04-15Clinical Trial Update: Phase II Study of Carboplatin and Bevacizumab (Avastin) for ER Neg, PR Neg, and HER2/Neu Neg Metastatic Breast Cancer [Phase 2]
Phase II trial of carboplatin plus bevacizumab for triple-negative metastatic breast cancer; the study was terminated and results were poste…
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CLINICAL_TRIALS withdrawal · 2014-02-12Clinical Trial Update: Oral Microencapsulated Diindolylmethane in Treating Patients With Stage II-III Triple Negative, Androgen Receptor Positive Breast Cancer Who Have Undergone Chemotherapy and Surgery [Phase 2]
The Phase 2 trial of oral microencapsulated diindolylmethane for stage II-III triple-negative, androgen receptor-positive breast cancer afte…
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CLINICAL_TRIALS withdrawal · 2014-02-06Clinical Trial Update: Azacitidine in Treating Patients With Triple Negative Stage I-IV Invasive Breast Cancer That Can Be Removed By Surgery [NA]
A clinical trial evaluating azacitidine for triple-negative breast cancer across stages I–IV and recurrent disease has been withdrawn (spons…
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CLINICAL_TRIALS withdrawal · 2014-01-28Clinical Trial Update: Vorinostat Before Surgery in Treating Patients With Triple-Negative Breast Cancer [NA]
The clinical trial evaluating vorinostat before surgery for Stage II/IIIA breast cancer, including triple-negative breast cancer, has been w…
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CLINICAL_TRIALS trial_result · 2014-01-14Clinical Trial Update: Study of SAR240550 (BSI-201) in Combination With Gemcitabine/Carboplatin, in Patients With Metastatic Triple Negative Breast Cancer [Phase 2]
Completed Phase 2 trial evaluating SAR240550 (BSI-201) in combination with gemcitabine and carboplatin for metastatic triple-negative breast…
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CLINICAL_TRIALS trial_result · 2013-09-30Clinical Trial Update: 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007) [Phase 1]
This Phase 1 clinical trial update evaluates the combination of 7-Hydroxystaurosporine and Irinotecan Hydrochloride in patients with metasta…
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CLINICAL_TRIALS trial_result · 2013-09-10Clinical Trial Update: BEATRICE Study: A Study of Bevacizumab (Avastin) Adjuvant Therapy in Triple Negative Breast Cancer [Phase 3]
The BEATRICE Phase 3 trial evaluating bevacizumab as adjuvant therapy in triple-negative breast cancer has completed, and results have been …
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CLINICAL_TRIALS research · 2013-07-23Clinical Trial Update: Triple Negative Breast Cancer Biomarker Study
A completed biomarker-focused clinical trial for metastatic triple-negative breast cancer sponsored by US Oncology Research.
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CLINICAL_TRIALS research · 2013-01-04Clinical Trial Update: Preoperative Chemotherapy in Triple Negative Invasive Breast Cancer That Can be Removed by Surgery. [Phase 2]
This entry describes a Phase 2 clinical trial evaluating preoperative chemotherapy for triple-negative invasive breast cancer that can be re…
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CLINICAL_TRIALS trial_result · 2012-12-28Clinical Trial Update: A Phase 2 Trial of Standard Chemotherapy, With or Without BSI-201, in Patients With Triple Negative Metastatic Breast Cancer [Phase 2]
Phase 2 trial assessing standard chemotherapy with or without BSI-201 (iniparib) for triple-negative metastatic breast cancer has completed.
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CLINICAL_TRIALS research · 2012-12-25Clinical Trial Update: A Phase III Trial of Carboplatin as Adjuvant Chemotherapy in Triple Negative Breast Cancer [Phase 3]
Phase III trial evaluating carboplatin as adjuvant chemotherapy for triple-negative breast cancer; current status is UNKNOWN.
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CLINICAL_TRIALS trial_result · 2012-12-03Clinical Trial Update: The Safety and Effects of Gefitinib in Triple-negative,EGFR Positive Metastatic Breast Cancer [Phase 2]
Phase 2 trial assessing safety and effects of gefitinib in patients with EGFR-positive triple-negative metastatic breast cancer.
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CLINICAL_TRIALS trial_result · 2012-10-10Clinical Trial Update: Cetuximab and Cisplatin in the Treatment of "Triple Negative" (Estrogen Receptor [ER] Negative, Progesterone Receptor [PgR] Negative, and Human Epidermal Growth Factor Receptor 2 [HER2] Negative) Metastatic Breast Cancer [Phase 2]
A Phase 2 trial evaluating cetuximab in combination with cisplatin for triple-negative metastatic breast cancer has completed, with results …
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CLINICAL_TRIALS trial_result · 2012-07-26Clinical Trial Update: A Phase II Trial of Gemcitabine and Oxaliplatin for Triple Negative Metastatic Breast Cancer [Phase 2]
A Phase II trial evaluating gemcitabine plus oxaliplatin for triple-negative metastatic breast cancer was terminated, with results posted in…
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CLINICAL_TRIALS trial_result · 2012-07-17Clinical Trial Update: Efficacy Study of Dasatinib in Locally Advanced Triple-Negative Breast Cancer Patients [Phase 2]
A Phase 2 study evaluating dasatinib in locally advanced triple-negative breast cancer was terminated, with results posted in 2012.
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CLINICAL_TRIALS withdrawal · 2012-06-26Clinical Trial Update: Maximum Tolerated Dose (MTD) of Liposomal Doxorubicin in Combination With Seliciclib for Patients With Metastatic Triple Negative Breast Cancer (TNBC) [Phase 1]
A Phase 1 trial evaluating the maximum tolerated dose of liposomal doxorubicin in combination with seliciclib for metastatic triple-negative…