Triple-negative Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-01-16Clinical Trial Update: A Study to Evaluate Rucaparib in Combination With Other Anticancer Agents in Participants With a Solid Tumor (SEASTAR) [Phase 1, Phase 2]
Phase 1/2 trial SEASTAR evaluating rucaparib in combination with other anticancer agents in solid tumors; study terminated with results post…
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CLINICAL_TRIALS trial_result · 2024-01-16Clinical Trial Update: Everolimus With Investigator's Choice of Chemotherapy in Advanced Triple-Negative Breast Cancer (TNBC) With Luminal Androgen Receptor (LAR) Subtype [Phase 3]
Phase 3 trial evaluating everolimus with investigator's choice chemotherapy in advanced triple-negative breast cancer with luminal androgen …
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CLINICAL_TRIALS trial_result · 2023-12-22Clinical Trial Update: Atezolizumab + Stereotactic Radiation in Triple-negative Breast Cancer and Brain Metastasis [Phase 2]
Phase 2 trial assessing atezolizumab plus stereotactic radiation for triple-negative breast cancer with brain metastases has completed enrol…
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CLINICAL_TRIALS trial_result · 2023-12-22Clinical Trial Update: An Umbrella Trial Based on Molecular Pathway for Patients With Metastatic TNBC. [Phase 2]
Phase 2 umbrella trial investigating molecular pathway-based treatment for patients with metastatic triple-negative breast cancer.
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CLINICAL_TRIALS trial_result · 2023-12-20Clinical Trial Update: Paclitaxel & Cyclophosphamide With or Without Trastuzumab Before Surgery in Treating Previously Untreated Breast Cancer [Phase 2]
Phase 2 trial evaluating paclitaxel and cyclophosphamide with or without trastuzumab before surgery in untreated breast cancer; results were…
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: Evaluating the Efficacy of Neratinib on Live Cell HER2 Signaling Transduction Analysis Positive Triple Negative Breast [Phase 2]
Phase 2 clinical trial investigating neratinib's effect on live cell HER2 signaling in triple negative breast cancer contexts.
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CLINICAL_TRIALS trial_result · 2023-12-15Clinical Trial Update: L-NMMA Plus Taxane Chemotherapy in Refractory Locally Advanced or Metastatic Triple Negative Breast Cancer Patients [Phase 1, Phase 2]
Clinical trial update for L-NMMA plus taxane chemotherapy in refractory locally advanced or metastatic triple-negative breast cancer (Phase …
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CLINICAL_TRIALS trial_result · 2023-12-14Clinical Trial Update: Neoantigen DNA Vaccine Alone vs. Neoantigen DNA Vaccine Plus Durvalumab in Triple Negative Breast Cancer Patients Following Standard of Care Therapy [Phase 1]
Phase 1 trial comparing a neoantigen DNA vaccine alone versus combined with durvalumab in triple-negative breast cancer after standard-of-ca…
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CLINICAL_TRIALS trial_result · 2023-12-04Clinical Trial Update: A Study to Evaluate TAlazoparib, Radiotherapy and Atezolizumab in gBRCA 1/2 Negative Patients With PD-L1+ Metastatic Triple Negative Breast Cancer [Phase 2]
Phase 2 study evaluating talazoparib, radiotherapy, and atezolizumab in gBRCA1/2-negative, PD-L1 positive metastatic triple-negative breast …
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CLINICAL_TRIALS trial_result · 2023-12-01Clinical Trial Update: Comparative Efficacy of Xiaopi Granules and Decoction in Triple-negative Breast Cancer: a Randomized Controlled Trial [Phase 2]
A Phase 2 randomized trial compares Xiaopi Granules to a decoction for efficacy in triple-negative breast cancer; results are not yet disclo…
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: A Phase II Study to Explore the Safety, Tolerability, and Preliminary Antitumor Activity of Sitravatinib Plus Tislelizumab or Combination With Nab-paclitaxel in Patients With Locally Recurrent or Metastatic Triple Negative Breast Cancer (TNBC) [Phase 2]
A Phase 2 clinical trial assessing safety, tolerability, and preliminary antitumor activity of Sitravatinib plus Tislelizumab or with Nab-pa…
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CLINICAL_TRIALS trial_result · 2023-11-09Clinical Trial Update: Neoadjuvant Pembrolizumab + Decitabine Followed by Std Neoadj Chemo for Locally Advanced HER2- Breast Ca [Phase 2]
Phase 2 trial evaluating neoadjuvant pembrolizumab plus decitabine followed by standard neoadjuvant chemotherapy for locally advanced HER2-n…
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CLINICAL_TRIALS trial_result · 2023-10-19Clinical Trial Update: Neoadjuvant Zoledronate and Atorvastatin in Triple Negative Breast Cancer [Phase 2]
Phase 2 trial update evaluating neoadjuvant zoledronate and atorvastatin in triple negative breast cancer has been completed.
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CLINICAL_TRIALS trial_result · 2023-10-06Clinical Trial Update: Carboplatin, Nab-Paclitaxel and Pembrolizumab for Metastatic Triple-Negative Breast Cancer [Phase 2]
Phase 2 trial of carboplatin, nab-paclitaxel, and pembrolizumab in metastatic triple-negative breast cancer completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: Randomized Controlled Trial of Genomically Directed Therapy in Patients With Triple Negative Breast Cancer [Phase 2]
Phase 2 randomized trial of genomically directed therapy in triple-negative breast cancer completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: Induction of Cisplatin/Nab-paclitaxel/Pembrolizumab Followed by Olaparib/Pembrolizumab Maintenance in mTNBC Patients [Phase 2]
Phase 2 clinical trial update investigating induction with cisplatin/nab-paclitaxel/pembrolizumab followed by olaparib/pembrolizumab mainten…
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by Surgery [Phase 1]
Phase 1 study of AZD8186, a PI3K-β inhibitor, in combination with docetaxel for patients with PTEN or PIK3CB-mutant advanced solid tumors, i…
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CLINICAL_TRIALS trial_result · 2023-09-14Clinical Trial Update: Randomized Phase 2 Study of Atezolizumab and Entinostat in Patients With aTN Breast Cancer With Phase 1b Lead In [Phase 1, Phase 2]
A randomized Phase 2 study evaluating the combination of atezolizumab and entinostat in advanced triple-negative breast cancer with a Phase …
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: Carboplatin With or Without Atezolizumab in Treating Patients With Stage IV Triple Negative Breast Cancer [Phase 2]
Phase 2 trial evaluating carboplatin with or without atezolizumab in Stage IV triple-negative breast cancer completed; results were posted i…
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CLINICAL_TRIALS trial_result · 2023-09-11Clinical Trial Update: LY3023414 and Prexasertib in Metastatic Triple-negative Breast Cancer [Phase 2]
Phase 2 clinical trial update for LY3023414 and Prexasertib in metastatic triple-negative breast cancer has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-07-03Clinical Trial Update: An Umbrella Trial Based on Molecular Pathway for Patients With Metastatic TNBC in First-line Treatment (FUTURE-Trop2) [Phase 1, Phase 2]
A multi-phase umbrella trial (FUTURE-Trop2) in first-line treatment for metastatic triple-negative breast cancer is ongoing, with Phase 1 an…
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: An Open-Label, Multicenter, Phase 1/2 Study of Poly(ADP-Ribose) Polymerase (PARP) Inhibitor E7449 as Single Agent in Subjects With Advanced Solid Tumors or With B-cell Malignancies and in Combination With Temozolomide (TMZ) or With Carboplatin and Paclitaxel in Subjects With Advanced Solid Tumors [Phase 1, Phase 2]
Open-label, multicenter Phase 1/2 trial evaluating PARP inhibitor E7449 as a single agent and in combination regimens for advanced solid tum…
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CLINICAL_TRIALS trial_result · 2023-06-08Clinical Trial Update: A Study of KN046 in Subjects With Locally Advanced or Metastatic Triple-negative Breast Cancer [Phase 1, Phase 2]
Clinical trial update for KN046 in locally advanced or metastatic triple-negative breast cancer completed phases 1 and 2.
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CLINICAL_TRIALS trial_result · 2023-06-06Clinical Trial Update: Short-term Sintilimab in Combination With Taxane and Carboplatin for Neoadjuvant Therapy in Triple-negative Breast Cancer [Phase 4]
A Phase 4 clinical trial evaluating short-term sintilimab in combination with a taxane and carboplatin as neoadjuvant therapy for triple-neg…
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CLINICAL_TRIALS trial_result · 2023-06-01Clinical Trial Update: Tavo and Pembrolizumab With or Without Chemotherapy in Patients With Inoperable Locally Advanced or Metastatic TNBC [Phase 2]
Phase 2 clinical trial update evaluating Tavo (talimogene laherparepvec) and pembrolizumab with or without chemotherapy in inoperable locall…