Triple-negative Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: Vaccination of Triple Negative Breast Cancer Patients [Phase 1, Phase 2]
Clinical trial update reporting completed Phase 1/Phase 2 results for a vaccination approach in patients with triple-negative breast cancer.
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CLINICAL_TRIALS other · 2024-06-27Clinical Trial Update: AN0025 and Pembrolizumab Combination in Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial update announcing AN0025 in combination with pembrolizumab for advanced solid tumors; the study includes several indi…
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CLINICAL_TRIALS research · 2024-06-27Clinical Trial Update: Effect of Huaier Granule on Adjuvant Treatment for High-risk Early-stage Triple-negative Breast Cancer [Phase 4]
Phase 4 clinical trial update on Huaier Granule as adjuvant treatment for high-risk early-stage triple-negative breast cancer; recruitment i…
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: EGFR/B7H3 CAR-T on Lung Cancer and Triple Negative Breast Cancer [EARLY_Phase 1]
This early-phase clinical trial evaluates an EGFR/B7H3-targeted CAR-T cell therapy for advanced lung cancer and advanced triple-negative bre…
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CLINICAL_TRIALS research · 2024-06-20Clinical Trial Update: Effects of MK-3475 (Pembrolizumab) on the Breast Tumor Microenvironment in Triple Negative Breast Cancer [Phase 1]
Ongoing Phase 1 study evaluating pembrolizumab (MK-3475) and its effects on the breast tumor microenvironment in triple-negative breast canc…
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CLINICAL_TRIALS trial_result · 2024-06-18Clinical Trial Update: Carboplatin and Paclitaxel With or Without Atezolizumab Before Surgery in Treating Patients With Newly Diagnosed, Stage II-III Triple-Negative Breast Cancer [Phase 2]
A phase II trial evaluating carboplatin and paclitaxel with or without atezolizumab before surgery in newly diagnosed stage II–III triple-ne…
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CLINICAL_TRIALS trial_result · 2024-06-12Clinical Trial Update: A Study of Sacituzumab With Chemoimmunotherapy to Treat Advanced Triple-Negative Breast Cancer After Prior Therapies [Phase 1, Phase 2]
A phase 1/2 study of sacituzumab in combination with chemoimmunotherapy for advanced triple-negative breast cancer has been terminated, with…
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CLINICAL_TRIALS research · 2024-06-07Clinical Trial Update: Gedatolisib Plus Talazoparib in Advanced Triple Negative or BRCA1/2 Positive, HER2 Negative Breast Cancers [Phase 1, Phase 2]
This clinical trial update outlines a Phase 1/2 study of Gedatolisib plus Talazoparib for advanced triple-negative breast cancer or BRCA1/2-…
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CLINICAL_TRIALS research · 2024-06-07Clinical Trial Update: Observational Study on the Sensitivity of Neoadjuvant Immunotherapy in Early Triple-Negative Breast Cancer
This observational study investigates the sensitivity of neoadjuvant immunotherapy in patients with early-stage triple-negative breast cance…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: First Line Atezolizumab, Paclitaxel, and Bevacizumab (Avastin®) in mTNBC [Phase 2]
This Phase 2 trial of first-line atezolizumab, paclitaxel, and bevacizumab in metastatic triple-negative breast cancer has completed.
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Carboplatin in EARLY Triple Negative Breast Cancer Trial (PEARLY Trial) [Phase 3]
Phase 3 trial evaluating carboplatin in early triple-negative breast cancer (PEARLY Trial) is currently active but not recruiting.
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CLINICAL_TRIALS other · 2024-06-04Clinical Trial Update: Evaluation of Recurrence Risk Factors in Locally Advanced Breast Cancer Patients Underwent Neoadjuvant Chemotherapy.
An ongoing clinical trial is evaluating recurrence risk factors in locally advanced breast cancer patients who underwent neoadjuvant chemoth…
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CLINICAL_TRIALS research · 2024-06-03Clinical Trial Update: Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer [Phase 3]
NRG Oncology is conducting a Phase 3 trial of doxorubicin hydrochloride and cyclophosphamide followed by paclitaxel with or without carbopla…
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CLINICAL_TRIALS research · 2024-05-28Clinical Trial Update: a Single-arm, Single-center, Open Clinical Study
This update notes a single-arm, single-center, open-label clinical trial that is currently recruiting, evaluating treatment across multiple …
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CLINICAL_TRIALS trial_result · 2024-05-24Clinical Trial Update: A Study to Evaluate Safety/Tolerability of Immunotherapy Combinations in Participants With Triple-Negative Breast Cancer or Gynecologic Malignancies [Phase 1]
Phase 1 study evaluating safety and tolerability of immunotherapy combinations in triple-negative breast cancer and ovarian cancer has compl…
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: Neoadjuvant Dose-dense EC Followed by ABX With PD-1 for Triple Negative Breast Cancer Patients [Phase 2]
Phase 2 neoadjuvant trial in triple-negative breast cancer evaluating dose-dense EC followed by ABX plus a PD-1 inhibitor; the study is curr…
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CLINICAL_TRIALS research · 2024-05-21Clinical Trial Update: A Study of ILB2109 and Toripalimab in Patients With Advanced Solid Malignancies [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating ILB2109 in combination with toripalimab in patients with advanced solid malignancies, currently recrui…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Neoadjuvant Nivolumab and Chemotherapy in Patients With Localized Triple-negative Breast Cancer [Phase 1, Phase 2]
Clinical trial update reporting results for neoadjuvant nivolumab in combination with chemotherapy for localized triple-negative breast canc…
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Association of Pembrolizumab Infusion Time and Efficacy in Patients With Non-metastatic Triple-negative Breast Cancer (TNBC) Treated With Neoadjuvant Chemotherapy and Immunotherapy
Clinical trial update investigating whether pembrolizumab infusion time affects efficacy in non-metastatic triple-negative breast cancer tre…
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CLINICAL_TRIALS trial_result · 2024-05-14Clinical Trial Update: Study of XL102 as Single-Agent and Combination Therapy in Subjects With Solid Tumors (QUARTZ-101) [Phase 1]
Exelixis reports that the QUARTZ-101 Phase 1 trial of XL102 as a single agent and in combination therapy for solid tumors has been terminate…
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CLINICAL_TRIALS research · 2024-05-10Clinical Trial Update: VISION: Triple Negative Breast Cancer Sample and Clinical Data Acquisition Study
The VISION study is an ongoing data- and sample-collection effort for triple-negative breast cancer. It enrolls by invitation to gather clin…
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CLINICAL_TRIALS withdrawal · 2024-05-10Clinical Trial Update: Hypnosis for Pain in Black Women With Advanced Breast Cancer: A Feasibility Study [NA]
A feasibility study evaluating hypnosis for pain in Black women with advanced breast cancer has been withdrawn.
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CLINICAL_TRIALS research · 2024-05-09Clinical Trial Update: Neoadjuvant Pembrolizumab, Carboplatin and Paclitaxel in Triple-negative Breast Cancer [Phase 2]
A Phase 2 neoadjuvant trial of pembrolizumab with carboplatin and paclitaxel in triple-negative breast cancer is currently not yet recruitin…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Early High-Risk TNBC Breast Cancer [Phase 2]
A Phase 2 trial evaluating QL1706 in combination with chemotherapy as neoadjuvant therapy for early high-risk triple-negative breast cancer;…
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CLINICAL_TRIALS trial_result · 2024-04-26Clinical Trial Update: Study of TT-00420 (Tinengotinib) Tablet as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1 and Phase 2 trials evaluated tinengotinib (TT-00420) as a monotherapy and in combination therapy for patients with advanced solid tu…