Triple-negative Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: MRI and Mammography Before Surgery in Patients With Stage I-II Breast Cancer [Phase 3]
Phase 3 study investigating MRI and mammography before surgery in patients with stage I–II breast cancer has completed; the cohort includes …
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: A Study of TAK-676 With Pembrolizumab After Radiation Therapy to Treat a Number of Cancers [Phase 1]
Phase 1 trial evaluating TAK-676 in combination with pembrolizumab after radiation therapy across several cancers; the study completed and p…
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CLINICAL_TRIALS other · 2025-09-04Clinical Trial Update: Sacituzumab Tirumotecan Plus Tagitanlimab in Previously Treated Locally Advanced or Metastatic Triple Negative Breast Cancer [Phase 2]
A Phase 2 clinical trial evaluating the combination of sacituzumab govitecan and tagitanlimab in previously treated locally advanced or meta…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Testing Two Different Drugs (Sacituzumab-govitecan and Trastuzumab-deruxtecan) Combinations Prescribed in an Alterning Pattern to Patients With Metastatic or Locally Advanced Triple-negative Breast Cancer [Phase 2]
A Phase 2 clinical trial is evaluating alternating regimens of Sacituzumab govitecan and Trastuzumab deruxtecan in patients with metastatic …
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CLINICAL_TRIALS withdrawal · 2025-09-02Clinical Trial Update: Targeting MDMD and PD1 in Tumors With Tertiary Lymphoid Structures [Phase 2]
Phase 2 trial targeting MDMD and PD-1 in tumors with tertiary lymphoid structures has been withdrawn; the study covered soft tissue sarcoma,…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Telemonitoring Platform "CUREETY TECHCARE" vs Standard of Care for mTBNC Patients Initiating a First-line Treatment [NA]
A clinical trial is evaluating the telemonitoring platform CUREETY TECHCARE versus standard of care for patients with metastatic triple-nega…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors [Phase 1]
Phase 1 study of MEM-288 oncolytic virus in advanced solid tumors, evaluating MEM-288 alone and in combination with standard-of-care therapy…
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Prevention of Sacituzumab Govitecan-related Neutropenia in Patients With Metastatic Triple Negative Breast Cancer [Phase 2]
Phase 2 trial update focusing on preventing sacituzumab govitecan–related neutropenia in metastatic triple-negative breast cancer; the study…
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: Capecitabine as Maintenance Therapy vs Observation in Early-stage Triple-negative Breast Cancer [Phase 2]
Phase 2 trial evaluating capecitabine as maintenance therapy versus observation in early-stage triple-negative breast cancer has completed.
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer [Phase 1, Phase 2]
A Phase 1/2 study of TC-510 from TCR2 Therapeutics in mesothelin-expressing cancers is active but not recruiting, spanning multiple indicati…
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Personalizing the Use of Pembrolizumab for Patients Who Have a Strong Response in Early Triple Negative Breast Cancer [Phase 3]
Phase 3 trial update exploring personalization of pembrolizumab use for patients with a strong early response in triple-negative breast canc…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Restoring Sensitivity To Immunotherapy In Advanced Triple Negative Breast Cancer Exploiting Ceralasertib Priming Followed By Combined Durvalumab/Nab-Paclitaxel [Phase 2]
A Phase 2 study evaluating ceralasertib priming followed by durvalumab and nab-paclitaxel in metastatic triple-negative breast cancer; curre…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Sacituzumab Tirumotecan Plus Anlotinib for Metastatic Triple Negative Breast Cancer [Phase 1, Phase 2]
Clinical trial update describing a Phase 1/Phase 2 study of sacituzumab govitecan plus anlotinib for metastatic triple-negative breast cance…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Implantable Microdevice for In Vivo Drug Sensitivity Testing in Patients With Early Stage, HER2-Positive or Triple Negative Breast Cancer [NA]
Completed clinical trial evaluating an implantable microdevice to test in vivo drug sensitivity in patients with early-stage HER2-positive o…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Comparison of the Breast Tumor Microenvironment
This document provides an update on a clinical trial studying the breast tumor microenvironment in breast cancer subtypes, including triple-…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy [Phase 2]
Phase 2 neoadjuvant breast cancer trial at Fudan University Shanghai Cancer Center evaluating a precision-platform therapy; the study is cur…
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EMA approval · 2025-08-21EMA Authorised: Trodelvy (sacituzumab govitecan) — Gilead Sciences Ireland UC
EMA authorised Sacituzumab govitecan (Trodelvy) for breast cancer, including triple-negative breast cancer, on 5 June 2025, with Gilead Scie…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA) [Phase 2]
Phase 2 trial ASPRIA is evaluating atezolizumab plus sacituzumab govitecan to prevent recurrence in triple-negative breast cancer, including…
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: A Study of ADRX-0706 in Select Advanced Solid Tumors [Phase 1]
Phase 1 study of ADRX-0706 in select advanced solid tumors is active/not recruiting, evaluating the investigational agent in triple-negative…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 clinical trial update on cabozantinib alone or with atezolizumab for locally advanced or metastatic solid tumors; the study lists mu…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Camrelizumab in Combination With Chemotherapy as Neoadjuvant Treatment in Patients With Early or Locally Advanced Triple-negative Breast Cancer [Phase 2]
A Phase 2 clinical trial is evaluating camrelizumab in combination with chemotherapy as neoadjuvant therapy for early or locally advanced tr…
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: Dose Escalation Study of mRNA-2752 for Intratumoral Injection to Participants in Advanced Malignancies [Phase 1]
Phase 1 dose-escalation and expansion study of intratumoral mRNA-2752 in advanced malignancies has completed, with expansion cohorts in seve…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-927 With ABBV-368, Budigalimab (ABBV-181) and/or Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 study to evaluate safety, tolerability, pharmacokinetics, and preliminary efficacy of ABBV-927 in combination with ABBV-368, Budigal…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: ProAgio in Combination With Gemcitabine in Patients With Metastatic Triple Negative Breast Cancer [Phase 1, Phase 2]
Ongoing Phase 1/2 trial evaluating ProAgio in combination with Gemcitabine for metastatic triple-negative breast cancer, with patient recrui…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: A Study on the Efficacy and Safety of Oral All-trans Retinoic Acid Combined With Toripalimab in TNBC. [NA]
A clinical study evaluating the efficacy and safety of combining oral all-trans retinoic acid with toripalimab in triple-negative breast can…