Triple-negative Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2025-12-08Clinical Trial Update: A Proof of Concept Window Trial of the IMmunological Effects of AveLumab and Aspirin in Triple-Negative Breast Cancer [Phase 2]
A Phase 2 window trial evaluating the immunological effects of avelumab and aspirin in triple-negative breast cancer has been withdrawn.
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: A Trial To Find Out If Vidutolimod Together With Cemiplimab Is Safe And If It Works In Adult Participants With Advanced Cancer Or Metastatic Cancer [Phase 2]
A Phase 2 trial evaluating Vidutolimod in combination with cemiplimab for adults with advanced or metastatic cancers was terminated, with re…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Sacituzumab Govitecan and Zimberelimab w/SRS in the Management of Metastatic Triple Negative Breast Cancer With Brain Metastases [Phase 1, Phase 2]
Clinical trial update for a combination of sacituzumab govitecan and zimberelimab with SRS in metastatic triple-negative breast cancer with …
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Nab-P+Cb+PD1 Inhibitors as Neoadjuvant Therapy for Early TNBC [Phase 2]
A Phase 2 clinical trial is evaluating nab-paclitaxel plus carboplatin and a PD-1 inhibitor as neoadjuvant therapy for early-stage triple-ne…
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CLINICAL_TRIALS other · 2025-12-05Clinical Trial Update: Clinical Study to Evaluate Debio0123 + Sacituzumab Govitecan Combination in TNBC or HR+/HER2- Advanced Breast Cancer [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating Debio0123 in combination with sacituzumab govitecan for advanced breast cancer (TNBC or HR+/HER2-); stud…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Ivermectin in Combination With Balstilimab or Pembrolizumab in Patients With Metastatic Triple Negative Breast Cancer [Phase 1, Phase 2]
A clinical trial evaluating ivermectin in combination with balstilimab or pembrolizumab for metastatic triple-negative breast cancer, in Pha…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Preventive stRategy for IMMU132-relatED AEs in TNBC or Luminal Breast Cancer- PRIMED [Phase 2]
A Phase 2 trial (PRIMED) evaluating a preventive strategy for IMMU132-related adverse events in triple-negative and HR+/HER2-negative breast…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Evaluation of a Plasma Protein Profile as a Predictive Biomarker for Metastatic Relapse in Triple Negative Breast Cancer Patients
A clinical trial evaluating whether a plasma protein profile can predict metastatic relapse in patients with triple-negative breast cancer; …
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Multicentre Study to Determine the Feasibility of Using an Integrated Consent Model to Compare Three Standard of Care Regimens for The Treatment of Triple-Negative Breast Cancer in the Neoadjuvant/Adjuvant Setting (REaCT-TNBC) [Phase 4]
A Phase 4 multicenter study (REaCT-TNBC) evaluating an integrated consent model while comparing three standard-of-care regimens for triple-n…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Reverse Triple Negative Immune Resistant Breast Cancer [Phase 2]
Phase 2 clinical trial investigating reversal of immune-resistant triple-negative breast cancer; currently recruiting at Fudan University.
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: The Optimal Radioimmunotherapy Combinations for Advanced TNBC [Phase 2]
Phase 2 clinical trial update on optimal radioimmunotherapy combinations for advanced triple-negative breast cancer; currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Pembrolizumab, IRX-2, and Chemotherapy in Triple Negative Breast Cancer [Phase 2]
Phase 2 trial update evaluating pembrolizumab with IRX-2 and chemotherapy in triple-negative breast cancer; the study is active but not recr…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Efficacy and Safety of Tenalisib in Patients With Metastatic Triple Negative Breast Cancer (TNBC) [Phase 2]
A Phase 2 clinical trial is evaluating Tenalisib for metastatic triple-negative breast cancer and is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Toripalimab Combined With Anthracycline-free or Anthracycline-containing Chemotherapy as Neoadjuvant Chemotherapy for Early Triple Negative Breast Cancer [Phase 2]
Phase 2 trial evaluating toripalimab with either anthracycline-free or anthracycline-containing chemotherapy as neoadjuvant treatment for ea…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: The TASTY-steering Study [NA]
A clinical trial update indicates that the TASTY-steering Study is currently recruiting for patients with metastatic triple-negative breast …
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: Bone Marrow Protection, Safety, Efficacy of Trilaciclib and Eribulin in Locally Advanced or Metastatic TNBC(Triple-negative Breast Cancer) [Phase 2]
This clinical trial update describes a Phase 2 study evaluating trilaciclib in combination with eribulin for locally advanced or metastatic …
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: TRIple Negative Breast Cancer Markers In Liquid Biopsies Using Artificial Intelligence
A clinical trial evaluating biomarkers for triple-negative breast cancer in liquid biopsies using artificial intelligence, currently recruit…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: TAO-Towards Optimal (Neo)Adjuvant Systemic Therapy of Stage III Triple-negative Breast Cancer
The Netherlands Cancer Institute is conducting a trial (NCT06931769) to optimize neoadjuvant/adjuvant systemic therapy for stage III triple-…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Triple-B Study;Carboplatin-cyclophosphamide Versus Paclitaxel With or Without Atezolizumab as First-line Treatment in Advanced Triple Negative Breast Cancer [Phase 2]
Phase 2 clinical trial update on the Triple-B study comparing carboplatin-cyclophosphamide versus paclitaxel with or without atezolizumab as…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: Olaparib & Radiation Therapy for Patients Triple Negative Breast Cancer (TNBC) [Phase 1]
A Phase 1 study evaluating olaparib in combination with radiation therapy for triple-negative breast cancer has completed.
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: A Study of QL1706 Combined With Short-Cycle Anthracyclines or Taxanes for the Treatment of Early-Stage TNBC [Phase 1]
Phase 1 clinical trial evaluating QL1706 in combination with short-cycle anthracyclines or taxanes for early-stage triple-negative breast ca…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Sac-TMT Combined With Toripalimab for First-line Treatment of PD-L1 Positive a/mTNBC [Phase 2]
A Phase 2 trial is evaluating Sac-TMT in combination with toripalimab as first-line therapy for PD-L1 positive advanced/metastatic triple-ne…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Neutrophil Biomarker Test for Predicting Clinical Benefit From Immunotherapy Based on Flow Cytometry Analysis
This clinical trial update describes a flow cytometry-based neutrophil biomarker test intended to predict clinical benefit from immunotherap…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: AMTEC IIT: Phase 2 Multiarm Study in TNBC [Phase 2]
Phase 2 multiarm AMTEC IIT trial in metastatic/triple-negative breast cancer has been terminated; results have been posted on 2025-11-21.
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CLINICAL_TRIALS withdrawal · 2025-11-21Clinical Trial Update: A Clinical Trial Assessing BT-001 Alone and in Combination With Pembrolizumab in Metastatic or Advanced Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 trial evaluating BT-001 alone and in combination with pembrolizumab in metastatic or advanced solid tumors has been terminated.