Triple-negative Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005) [Phase 2]
Phase 2 trial evaluating pembrolizumab plus lenvatinib in previously treated patients with select solid tumors; results on efficacy and safe…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Study of BDC-3042 as Single Agent and in Combination With Cemiplimab in Patients With Advanced Malignancies [Phase 1]
This clinical trial update notes the termination of a Phase 1 study of BDC-3042 as a single agent and in combination with cemiplimab in pati…
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CLINICAL_TRIALS trial_result · 2025-11-14Clinical Trial Update: A Study of FAZ053 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies. [Phase 1]
This Phase 1 trial of FAZ053 as a single agent and in combination with PDR001 in patients with advanced malignancies has been terminated.
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: A Study of the Efficacy and Safety of Atezolizumab Plus Chemotherapy for Patients With Early Relapsing Recurrent Triple-Negative Breast Cancer [Phase 3]
Phase 3 trial evaluating atezolizumab plus chemotherapy for patients with early relapsing recurrent triple-negative breast cancer has comple…
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: Abemaciclib in Treating Patients With Surgically Resectable, Chemotherapy Resistant, Triple Negative Breast Cancer [Phase 2]
A Phase 2 trial of abemaciclib for surgically resectable, chemotherapy-resistant triple-negative breast cancer was terminated.
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Women's MoonShot: Neoadjuvant Treatment With PaCT for Patients With Locally Advanced TNBC [Phase 2]
Phase 2 neoadjuvant trial (PaCT) for locally advanced triple-negative breast cancer has completed with results posted on 2025-11-06.
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: NUV-868 as Monotherapy and in Combination With Olaparib or Enzalutamide in Adult Patients With Advanced Solid Tumors [Phase 1]
This Phase 1 trial update reports termination of NUV-868 as monotherapy and in combination with olaparib or enzalutamide in adults with adva…
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CLINICAL_TRIALS trial_result · 2025-11-05Clinical Trial Update: Study of Boserolimab (MK-5890) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Adults With Advanced Solid Tumors (MK-5890-001) [Phase 1]
Phase 1 study evaluating Boserolimab (MK-5890) alone and in combination with Pembrolizumab (MK-3475) in adults with advanced solid tumors; t…
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CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer [Phase 1, Phase 2]
Phase I/II study evaluating VLS-1488 in adults with advanced cancer; the trial is currently recruiting across multiple solid-tumor indicatio…
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CLINICAL_TRIALS trial_result · 2025-10-30Clinical Trial Update: Crizotinib in Lobular Breast, Diffuse Gastric and Triple Negative Lobular Breast Cancer or CDH1-mutated Solid Tumours [Phase 2]
Phase 2 clinical trial of crizotinib completed in invasive lobular breast cancer, gastric cancer, and triple-negative breast cancer populati…
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CLINICAL_TRIALS trial_result · 2025-10-29Clinical Trial Update: Study of Pembrolizumab (MK-3475) Plus Chemotherapy vs Placebo Plus Chemotherapy as Neoadjuvant Therapy and Pembrolizumab vs Placebo as Adjuvant Therapy in Participants With Triple Negative Breast Cancer (TNBC) (MK-3475-522/KEYNOTE-522) [Phase 3]
The Phase 3 KEYNOTE-522 trial evaluating pembrolizumab with chemotherapy as neoadjuvant therapy and pembrolizumab as adjuvant therapy in tri…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: A Study of HMBD-002, a Monoclonal Antibody Targeting VISTA, as Monotherapy and Combined With Pembrolizumab, in Patients With Advanced Solid Tumors [Phase 1]
This is a completed Phase 1 trial of HMBD-002, a VISTA-targeting monoclonal antibody, as monotherapy and with pembrolizumab in patients with…
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: Axillary Nodal Burden in HER2+ and TNBC
A completed clinical trial update evaluating axillary nodal burden in HER2-positive and triple-negative breast cancer.
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CLINICAL_TRIALS trial_result · 2025-10-07Clinical Trial Update: A Study of ZEN003694 and Talazoparib in Patients With Triple Negative Breast Cancer [Phase 2]
A Phase 2 study tested ZEN003694 in combination with talazoparib in triple-negative breast cancer, but the trial was terminated and results …
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Study of Magrolimab Combination Therapy in Patients With Non-Surgically Removable Locally Advanced or Metastatic Triple-Negative Breast Cancer [Phase 2]
Phase 2 trial of magrolimab in combination therapy for locally advanced or metastatic triple-negative breast cancer has been terminated and …
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Adjuvant PVX-410 Vaccine and Durvalumab in Stage II/III Triple Negative Breast Cancer [Phase 1]
Phase 1 clinical trial update evaluating adjuvant PVX-410 vaccine in combination with durvalumab for stage II/III triple-negative breast can…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Nab-paclitaxel and Alpelisib for the Treatment of Anthracycline Refractory Triple Negative Breast Cancer With PIK3CA or PTEN Alterations [Phase 2]
A Phase 2 trial evaluating nab-paclitaxel in combination with alpelisib for anthracycline-refractory triple-negative breast cancer with PIK3…
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CLINICAL_TRIALS trial_result · 2025-09-23Clinical Trial Update: The Role of Bexarotene in Inducing Susceptibility to Chemotherapy in Metastatic TNBC [Phase 1]
Phase 1 study evaluating whether bexarotene can increase chemotherapy sensitivity in metastatic triple-negative breast cancer has completed …
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CLINICAL_TRIALS trial_result · 2025-09-17Clinical Trial Update: NeoAdjuvant Therapy Comparing Sacituzumab Govitecan+Pembrolizumab vs. SoC Chemotherapy in Clinical Stage II-III, Triple-negative Early Breast Cancer [Phase 3]
Phase 3 trial evaluating neoadjuvant Sacituzumab Govitecan plus Pembrolizumab versus standard-of-care chemotherapy in clinical stage II-III …
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies [Phase 1]
Ongoing Phase 1 safety/efficacy trial of CID-078 in patients with advanced/metastatic solid tumors; study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Leronlimab (PRO 140) Combined With Carboplatin in Patients With Cytokine Chemokine Receptor 5 Positive (CCR5+) mTNBC [Phase 1, Phase 2]
A Phase 1/2 study evaluating leronlimab (PRO 140) in combination with carboplatin for CCR5-positive metastatic triple-negative breast cancer…
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer [Phase 1]
Phase 1 trial update of PeptiCRAd-1 reports safety signals and anti-tumor activity across multiple cancers; trial status is ACTIVE_NOT_RECRU…
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: MRI and Mammography Before Surgery in Patients With Stage I-II Breast Cancer [Phase 3]
Phase 3 study investigating MRI and mammography before surgery in patients with stage I–II breast cancer has completed; the cohort includes …
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: A Study of TAK-676 With Pembrolizumab After Radiation Therapy to Treat a Number of Cancers [Phase 1]
Phase 1 trial evaluating TAK-676 in combination with pembrolizumab after radiation therapy across several cancers; the study completed and p…
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: Capecitabine as Maintenance Therapy vs Observation in Early-stage Triple-negative Breast Cancer [Phase 2]
Phase 2 trial evaluating capecitabine as maintenance therapy versus observation in early-stage triple-negative breast cancer has completed.