Triple-negative Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: An Open-Label, Multicenter, Phase 1/2 Study of Poly(ADP-Ribose) Polymerase (PARP) Inhibitor E7449 as Single Agent in Subjects With Advanced Solid Tumors or With B-cell Malignancies and in Combination With Temozolomide (TMZ) or With Carboplatin and Paclitaxel in Subjects With Advanced Solid Tumors [Phase 1, Phase 2]
Open-label, multicenter Phase 1/2 trial evaluating PARP inhibitor E7449 as a single agent and in combination regimens for advanced solid tum…
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CLINICAL_TRIALS trial_result · 2023-06-08Clinical Trial Update: A Study of KN046 in Subjects With Locally Advanced or Metastatic Triple-negative Breast Cancer [Phase 1, Phase 2]
Clinical trial update for KN046 in locally advanced or metastatic triple-negative breast cancer completed phases 1 and 2.
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CLINICAL_TRIALS trial_result · 2023-06-06Clinical Trial Update: Short-term Sintilimab in Combination With Taxane and Carboplatin for Neoadjuvant Therapy in Triple-negative Breast Cancer [Phase 4]
A Phase 4 clinical trial evaluating short-term sintilimab in combination with a taxane and carboplatin as neoadjuvant therapy for triple-neg…
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CLINICAL_TRIALS trial_result · 2023-06-01Clinical Trial Update: Tavo and Pembrolizumab With or Without Chemotherapy in Patients With Inoperable Locally Advanced or Metastatic TNBC [Phase 2]
Phase 2 clinical trial update evaluating Tavo (talimogene laherparepvec) and pembrolizumab with or without chemotherapy in inoperable locall…
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CLINICAL_TRIALS trial_result · 2023-05-25Clinical Trial Update: Effect of Platinum-based Versus Non-platinum-based Neoadjuvant Chemotherapy in Triple-negative Breast Cancer [Phase 2]
Phase 2 clinical trial comparing platinum-based versus non-platinum-based neoadjuvant chemotherapy in triple-negative breast cancer.
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CLINICAL_TRIALS trial_result · 2023-05-09Clinical Trial Update: TAK-228 and TAK-117 Followed by Cisplatin and Nab Paclitaxel for Metastatic Triple Negative Breast Cancer [Phase 2]
Phase 2 trial in metastatic triple negative breast cancer evaluating TAK-228 and TAK-117 followed by cisplatin and nab-paclitaxel has comple…
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CLINICAL_TRIALS trial_result · 2023-05-06Clinical Trial Update: A Phase 3 Study Comparing Carelizumab Plus Nab-paclitaxel and Apatinib, Carelizumab Plus Nab-paclitaxel, and Nab-paclitaxel in Patients With Advanced Triple Negative Breast Cancer. [Phase 3]
Phase 3 trial comparing Carelizumab plus nab-paclitaxel with/apatinib, Carelizumab plus nab-paclitaxel, and nab-paclitaxel in advanced tripl…
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CLINICAL_TRIALS trial_result · 2023-04-26Clinical Trial Update: A Trial Evaluating the Efficacy and Safety of EndoTAG®-1 in Combination With Paclitaxel and Gemcitabine Compared With Paclitaxel and Gemcitabine as First-line Therapy in Patients With Visceral Metastatic Triple-negative Breast Cancer [Phase 3]
Phase 3 trial evaluating EndoTAG-1 in combination with paclitaxel and gemcitabine vs paclitaxel and gemcitabine as first-line therapy for vi…
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CLINICAL_TRIALS trial_result · 2023-04-12Clinical Trial Update: A Phase II Trial of Camrelizumab in Combination With Apatinib for Neoadjuvant Treatment of Early-stage TNBC With a High Proportion of TILs [Phase 2]
Phase II trial evaluating camrelizumab plus apatinib as neoadjuvant therapy for early-stage triple-negative breast cancer with high tumor-in…
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CLINICAL_TRIALS trial_result · 2023-04-10Clinical Trial Update: Bintrafusp Alfa in High Mobility Group AT-Hook 2 (HMGA2) Expressing Triple Negative Breast Cancer [Phase 2]
Phase 2 trial of Bintrafusp Alfa in HMGA2-expressing triple-negative breast cancer was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2023-04-06Clinical Trial Update: Surufatinib Combined With Tislelizumab in the Second-line and Further Treatment of Triple-negative Breast Cancer [Phase 1, Phase 2]
A clinical trial update for surufatinib combined with tislelizumab in second-line and beyond for metastatic triple-negative breast cancer (P…
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CLINICAL_TRIALS trial_result · 2023-03-29Clinical Trial Update: Pegylated Liposomal Doxorubicin Hydrochloride and Carboplatin Followed by Surgery and Paclitaxel in Treating Patients With Triple Negative Stage II-III Breast Cancer [Phase 2]
Phase 2 trial evaluating pegylated liposomal doxorubicin hydrochloride and carboplatin followed by surgery and paclitaxel in triple-negative…
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CLINICAL_TRIALS trial_result · 2023-03-21Clinical Trial Update: Ipatasertib in Combination With Carboplatin, Carboplatin/Paclitaxel, or Capecitabine/Atezolizumab in Treating Patients With Metastatic Triple Negative Breast Cancer [Phase 1, Phase 2]
Phase 1/2 trial updates ipatasertib in combination with chemotherapy/immunotherapy regimens for metastatic triple-negative breast cancer; co…
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CLINICAL_TRIALS trial_result · 2023-03-13Clinical Trial Update: A Dose Escalation and Cohort Expansion Study of NKTR-214 in Combination With Nivolumab and Other Anti-Cancer Therapies in Patients With Select Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 trial evaluating NKTR-214 in combination with nivolumab and other anti-cancer therapies in select advanced solid tumors completed …
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CLINICAL_TRIALS trial_result · 2023-03-10Clinical Trial Update: Carboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Locally Advanced or Inflammatory Triple Negative Breast Cancer [Phase 2]
A Phase 2 trial exploring pre-surgical treatment with carboplatin and an albumin-stabilized nanoparticle formulation of paclitaxel in patien…
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CLINICAL_TRIALS trial_result · 2023-03-08Clinical Trial Update: REVEAL Study of NKTR-262 in Combination With NKTR-214 and Nivolumab in Patients With Locally Advanced / Metastatic Solid Tumor Malignancies [Phase 1, Phase 2]
Phase 1/2 trial REVEAL exploring NKTR-262 with NKTR-214 and nivolumab in various locally advanced/metastatic solid tumors was terminated; re…
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CLINICAL_TRIALS trial_result · 2023-03-03Clinical Trial Update: A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors [Phase 1, Phase 2]
A Phase I/II study investigating regorafenib in combination with avelumab in various solid tumors, spanning Phase 1 and Phase 2 cohorts.
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CLINICAL_TRIALS trial_result · 2023-02-28Clinical Trial Update: A Trial Exploring the Opportune Administration of Nab-paclitaxel in the First Line Treatment, Camrelizumab Combined With Nab-paclitaxel and Famitinib, of TNBC. [Phase 2]
Phase 2 trial exploring nab-paclitaxel with camrelizumab and famitinib in first-line triple-negative breast cancer.
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CLINICAL_TRIALS trial_result · 2023-02-28Clinical Trial Update: Chidamide in Combination With Vincristine Metronomic Chemotherapy for Advanced Triple-negative Breast Cancer [Phase 1, Phase 2]
A clinical trial update for chidamide in combination with vincristine metronomic chemotherapy in advanced triple-negative breast cancer, cur…
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CLINICAL_TRIALS trial_result · 2023-02-21Clinical Trial Update: [18F]-DPA-714 PET/CT (Positron Emission Tomography/Computerized Tomography) in Triple Negative Breast Cancers [Phase 2]
A Phase 2 clinical trial evaluating 18F-DPA-714 PET/CT in patients with triple negative breast cancer has completed.
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CLINICAL_TRIALS trial_result · 2023-02-21Clinical Trial Update: Phase II Trial of Talazoparib in BRCA1/2 Wild-type HER2-negative Breast Cancer and Other Solid Tumors [Phase 2]
Phase II trial update of talazoparib in BRCA1/2 wild-type, HER2-negative breast cancer and other solid tumors has completed with results pos…
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CLINICAL_TRIALS trial_result · 2023-02-16Clinical Trial Update: Sintilimab and Bevacizumab Biosimilar Combined With PLD in mTNBC [Phase 2]
A Phase 2 clinical trial evaluating sintilimab and bevacizumab biosimilar in combination with pegylated liposomal doxorubicin for metastatic…
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CLINICAL_TRIALS trial_result · 2023-02-01Clinical Trial Update: Neoadjuvant Carbo/Paclitaxel Followed by Doxorubicin/Cyclophosphamide in Breast Cancer [Phase 2]
A Phase 2 neoadjuvant trial in breast cancer, including triple-negative cases, evaluated carboplatin/paclitaxel followed by doxorubicin/cycl…
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CLINICAL_TRIALS trial_result · 2023-02-01Clinical Trial Update: A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 study of GEN1044 (DuoBody-CD3x5T4) in malignant solid tumors has been terminated with posted results.
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CLINICAL_TRIALS trial_result · 2023-01-31Clinical Trial Update: A Study of Navicixizumab Monotherapy or in Combination in Patients With Select Advanced Solid Tumors [Phase 2]
Phase 2 study evaluating Navicixizumab as monotherapy or in combination in patients with select advanced solid tumors, including colorectal …