Triple-negative Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63) [Phase 3]
A Phase 3 randomized trial evaluating sacituzumab govitecan-hziy in combination with pembrolizumab versus physician's choice in triple-negat…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400 [Phase 1]
Phase 1 study assessing adverse events and change in disease activity in adults with select advanced solid tumors treated with ABBV-400; the…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Neoadjuvant Chemotherapy Combined With Sintilimab and Bevacizumab for TNBC (NEOTORCH-BREAST07) [Phase 2]
A Phase 2 neoadjuvant trial evaluating the combination of sintilimab and bevacizumab with chemotherapy for triple-negative breast cancer; th…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Neoadjuvant INBRX-106 in Combination With Pembrolizumab for Stage II/III TNBC Patients [Phase 2]
Phase 2 neoadjuvant trial evaluating INBRX-106 with pembrolizumab for stage II/III triple-negative breast cancer is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Neoadjuvant Therapy and Contrast-enhanced Mammography for Early Stage Breast Cancer [EARLY_Phase 1]
A Phase 1 EARLY study evaluating neoadjuvant therapy plus contrast-enhanced mammography for early-stage breast cancer is currently recruitin…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Development of a Multi-omics Prediction Model for Immunotherapy Response in Triple-Negative Breast Cancer Subtypes
It reports a clinical trial developing a multi-omics model to predict immunotherapy response in triple-negative breast cancer subtypes; the …
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: A Prospective, Open-label, Single-arm, Exploratory Clinical Trial to Evaluate the Safety and Tolerability of 225Ac-TR2205 Injection in Patients With Triple-negative Breast Cancer. [EARLY_Phase 1]
A Phase 1, open-label, single-arm study assessing the safety and tolerability of 225Ac-TR2205 injection in patients with advanced metastatic…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Neoadjuvant Chemotherapy Combined With Toripalimab for TNBC (NEOTORCH-BREAST02) [Phase 2]
Phase 2 NEOTORCH-BREAST02 trial is evaluating neoadjuvant chemotherapy with toripalimab in triple-negative breast cancer. The study is curre…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Feasibility of a Lifestyle Intervention for Women With Triple-negative Breast Cancer Under Neoadjuvant Immunotherapy [NA]
A clinical trial update describing a feasibility study of a lifestyle intervention for women with triple-negative breast cancer undergoing n…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Systemic Anti-Cancer Therapy Dose Modifications for Individuals With Duffy Null Phenotype [Phase 1]
A Phase 1 trial evaluating dose modifications of systemic anti-cancer therapy in individuals with the Duffy null phenotype. The study enroll…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: A Study of LY4170156 in Participants With Selected Advanced Solid Tumors [Phase 1]
An early-phase study evaluating LY4170156 in selected advanced solid tumors is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: ctDNA Positive Patients Diagnosed With cT1bN0 and cT1cN0 TNBC
This ClinicalTrials.gov listing provides an update on a study involving ctDNA-positive patients with early-stage triple-negative breast canc…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: ZAP-IT: ZN-c3 + Carboplatin + Pembrolizumab in mTNBC [Phase 1, Phase 2]
Phase 1/2 clinical trial of ZN-c3 combined with carboplatin and pembrolizumab for metastatic triple-negative breast cancer, currently listed…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: A Study of Olaparib and Pembrolizumab in People With Triple Negative Breast Cancer (TNBC) or Hormone Receptor-positive HER2-negative Breast Cancer [Phase 2]
Phase 2 trial evaluating the combination of olaparib and pembrolizumab in triple-negative breast cancer and hormone receptor-positive, HER2-…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Assessement of Potential Interest of [68Ga]Ga-PentixaFor PET/CT in Metastatic Triple Negative Breast Cancer Patients [NA]
This clinical trial update describes the assessment of the PET imaging tracer [68Ga]Ga-PentixaFor for potential use in detecting metastatic …
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: MRI-Guided Neoadjuvant Treatment De-Escalation in Stage II-III TNBC [Phase 2]
This clinical trial update notes a Phase 2 study evaluating MRI-guided neoadjuvant treatment de-escalation in stage II-III triple-negative b…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies
A clinical trial funded by Elephas is exploring a biomarker-based method to predict response to immunotherapy using live tumor biopsies; the…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas [Phase 1]
DR-0202 is being studied in a Phase 1 trial across multiple locally advanced or metastatic carcinomas; the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors [Phase 1, Phase 2]
APL-5125 is being studied in a Phase 1/2 trial for adults with advanced solid tumors, with recruitment ongoing across several indications in…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: fREEDOM: REsonance for Early Detection Of Breast Cancer Metastases [NA]
The fREEDOM trial for Resonance for Early Detection Of Breast Cancer Metastases is currently recruiting participants with invasive breast ca…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: A Single-Arm Phase Ⅱ Study of Fluzoparib Maintenance in Platinum-sensitive Advanced Triple-Negative Breast Cance [Phase 2]
A single-arm Phase II trial evaluating maintenance therapy with Fluzoparib in platinum-sensitive advanced triple-negative breast cancer. The…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Atezolizumab and Chemotherapy Treatment as T-cell Activators in Metastatic Triple Negative Breast Cancer Patients [Phase 2]
Phase 2 clinical trial evaluating atezolizumab in combination with chemotherapy for metastatic triple-negative breast cancer is currently re…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Prediction of Radiotherapy Efficacy in Patients With Triple-negative Breast Cancer [NA]
Clinical trial update describing a study on predicting radiotherapy efficacy in triple-negative breast cancer; the trial is currently active…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Radiological Prediction of Response to Neoadjuvant Chemoimmunotherapy for Triple-negative Breast Cancer [NA]
A clinical trial update describing a study that aims to predict radiological response to neoadjuvant chemoimmunotherapy in patients with tri…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: mTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovarian [Phase 1]
A Phase 1 study investigating AZD2014 (an mTORC1/2 inhibitor) or AZD5363 (an AKT inhibitor) in recurrent endometrial and ovarian cancers, wi…