Triple-negative Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Cardiac Outcomes With Near-Complete Estrogen Deprivation [NA]
This entry reports an ongoing Duke University clinical trial evaluating cardiac outcomes in patients with breast cancer undergoing near-comp…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer [Phase 2]
This Clinical Trials update describes the I-SPY TRIAL, a Phase 2 neoadjuvant breast cancer study using personalized adaptive agents; recruit…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Camrelizumab Plus Risedronate and Chemotherapy for Triple-Negative Breast Cancer: An Exploratory Clinical Study on Mechanisms and Efficacy [Phase 2]
A Phase 2 exploratory clinical study is evaluating camrelizumab plus risedronate and chemotherapy for triple-negative breast cancer, focusin…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors [Phase 1]
Phase 1 study evaluating NKT5097 in adults with advanced or metastatic solid tumors, including various breast cancer subtypes and gynecologi…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Serplulimab Combined With Trastuzumab Rezetecan as Neoadjuvant Therapy for Triple-Negative Breast Cancer [Phase 2]
This document describes a Phase 2 trial evaluating serplulimab in combination with SHR-A1811 as neoadjuvant therapy for triple-negative brea…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Feasibility of Serial Multisite Image-guided Biopsy to Study Breast Cancer Evolution
This clinical trial update describes a feasibility study using serial image-guided biopsies across multiple sites to study how breast cancer…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform
This clinical trial update describes the use of a live tumor diagnostic platform to evaluate immune checkpoint inhibitor responses across mu…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: A Dose Finding Phase 1 of Sarilumab Plus Capecitabine in HER2/Neu-Negative Metastatic Breast Cancer and a Single-arm, Historically-controlled Phase 2 Study of Sarilumab Plus Capecitabine in Stage I-III Triple Negative Breast Cancer With High-Risk Residual Disease (EMPOWER) [Phase 1, Phase 2]
This trial update covers a dose-finding Phase 1 study of sarilumab plus capecitabine in HER2-negative metastatic breast cancer and a Phase 2…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Peritumoral and Periganglionic Infiltration of Levobupivacaine Prior to Conservative Surgery for Triple-negative Breast Cancer [Phase 2]
A Phase 2 clinical trial evaluating peritumoral and periganglionic infiltration of levobupivacaine before conservative surgery in triple-neg…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy [NA]
A multicenter MD Anderson trial investigates eliminating breast cancer surgery or radiotherapy in exceptional responders to neoadjuvant syst…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Neoadjuvant Toripalimab Plus SBRT for Chemo-Resistant Triple-Negative Breast Cancer [Phase 2]
Phase 2 trial investigating neoadjuvant toripalimab with stereotactic body radiotherapy for chemo-resistant triple-negative breast cancer, c…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies
A study led by Tempus AI is evaluating minimal residual disease in breast cancer by longitudinal ctDNA profiling to track disease status acr…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Open-label, Single Center, Single-arm, Phase 2 Study of Neoadjuvant Pembrolizumab in Combination With Carboplatin and Paclitaxel in Patients With Stage 1 cT1b-T1cN0M0 Triple Negative Breast Cancer [Phase 2]
An open-label, single-center, single-arm Phase 2 trial assessing neoadjuvant pembrolizumab in combination with carboplatin and paclitaxel fo…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Microbiome Immunotherapy Neoadjuvant Assessment
The University College Cork-sponsored trial is evaluating microbiome-based immunotherapy as neoadjuvant treatment for triple-negative breast…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: First in Human Study of TUB-030 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
First-in-human study of TUB-030 is underway in patients with advanced solid tumors, including head and neck squamous cell carcinoma, small c…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Triple-Negative Breast Cancer [Phase 2]
A Phase 2 clinical trial is evaluating QL1706 in combination with chemotherapy as neoadjuvant therapy for triple-negative breast cancer and …
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Phase II, Single-arm Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Eribulin in Pretreated Advanced Triple-negative Breast Cancer Harboring a PIK3CA Mutation [Phase 2]
A Phase II, single-arm trial evaluating the efficacy and safety of Inavolisib in combination with Eribulin in pretreated advanced triple-neg…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addition to Standard of Care Treatment for Cancer That Has Spread Beyond the Original Site of Disease [Phase 2]
A Phase 2 clinical trial is evaluating whether adding stereotactic body radiotherapy to standard of care improves outcomes for patients with…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC [Phase 2]
Phase 2 clinical trial update on sacituzumab govitecan with or without pembrolizumab for metastatic triple-negative breast cancer, currently…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Safety Study of MELK Inhibitor to Treat Patients With Advanced Breast Cancer and Triple Negative Breast Cancer [Phase 1]
Phase 1 safety study of a MELK inhibitor for advanced breast cancer including triple-negative breast cancer is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Posaconazole Plus PD-1 Inhibitors and Chemotherapy vs PD-1 Inhibitors and Chemotherapy in Neoadjuvant Therapy for Triple Negative Breast Cancer [Phase 2]
Phase 2 neoadjuvant trial evaluating posaconazole plus PD-1 inhibitors and chemotherapy versus PD-1 inhibitors and chemotherapy in triple-ne…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer [Phase 1]
This clinical trial update announces the first-in-human, Phase 1 study of ATX-295, an oral inhibitor of KIF18A, in patients with advanced or…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: PQ203 in Advanced Malignant Tumors Including Triple Negative Breast Cancer [Phase 1]
PQ203 from ProteinQure Inc. is in a Phase 1 trial for advanced malignant tumors, including triple-negative breast cancer, and recruitment is…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Pembrolizumab + Paclitaxel +/- Bevacizumab for Triple-negative Breast Cancer [Phase 2]
Phase 2 clinical trial evaluating pembrolizumab with paclitaxel, with or without bevacizumab, for recurrent triple-negative breast cancer; r…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Personalised Neoantigen-targeting Cancer Vaccine NECVAX-NEO1 in Neoadjuvant Triple-negative Breast Cancer [Phase 1, Phase 2]
A phase 1/2 clinical trial investigating a personalized neoantigen-targeting cancer vaccine (NECVAX-NEO1) for neoadjuvant treatment in tripl…