Triple-negative Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-06-07Clinical Trial Update: Gedatolisib Plus Talazoparib in Advanced Triple Negative or BRCA1/2 Positive, HER2 Negative Breast Cancers [Phase 1, Phase 2]
This clinical trial update outlines a Phase 1/2 study of Gedatolisib plus Talazoparib for advanced triple-negative breast cancer or BRCA1/2-…
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CLINICAL_TRIALS research · 2024-06-07Clinical Trial Update: Observational Study on the Sensitivity of Neoadjuvant Immunotherapy in Early Triple-Negative Breast Cancer
This observational study investigates the sensitivity of neoadjuvant immunotherapy in patients with early-stage triple-negative breast cance…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Carboplatin in EARLY Triple Negative Breast Cancer Trial (PEARLY Trial) [Phase 3]
Phase 3 trial evaluating carboplatin in early triple-negative breast cancer (PEARLY Trial) is currently active but not recruiting.
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CLINICAL_TRIALS research · 2024-06-03Clinical Trial Update: Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer [Phase 3]
NRG Oncology is conducting a Phase 3 trial of doxorubicin hydrochloride and cyclophosphamide followed by paclitaxel with or without carbopla…
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CLINICAL_TRIALS research · 2024-05-28Clinical Trial Update: a Single-arm, Single-center, Open Clinical Study
This update notes a single-arm, single-center, open-label clinical trial that is currently recruiting, evaluating treatment across multiple …
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CLINICAL_TRIALS research · 2024-05-21Clinical Trial Update: A Study of ILB2109 and Toripalimab in Patients With Advanced Solid Malignancies [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating ILB2109 in combination with toripalimab in patients with advanced solid malignancies, currently recrui…
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Association of Pembrolizumab Infusion Time and Efficacy in Patients With Non-metastatic Triple-negative Breast Cancer (TNBC) Treated With Neoadjuvant Chemotherapy and Immunotherapy
Clinical trial update investigating whether pembrolizumab infusion time affects efficacy in non-metastatic triple-negative breast cancer tre…
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CLINICAL_TRIALS research · 2024-05-10Clinical Trial Update: VISION: Triple Negative Breast Cancer Sample and Clinical Data Acquisition Study
The VISION study is an ongoing data- and sample-collection effort for triple-negative breast cancer. It enrolls by invitation to gather clin…
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CLINICAL_TRIALS research · 2024-05-09Clinical Trial Update: Neoadjuvant Pembrolizumab, Carboplatin and Paclitaxel in Triple-negative Breast Cancer [Phase 2]
A Phase 2 neoadjuvant trial of pembrolizumab with carboplatin and paclitaxel in triple-negative breast cancer is currently not yet recruitin…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Early High-Risk TNBC Breast Cancer [Phase 2]
A Phase 2 trial evaluating QL1706 in combination with chemotherapy as neoadjuvant therapy for early high-risk triple-negative breast cancer;…
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CLINICAL_TRIALS research · 2024-04-26Clinical Trial Update: Utidelone (UTD1) Plus Capecitabine in Non-pCR TNBC After Neoadjuvant Therapy [Phase 2]
A Phase 2 study evaluating utidelone (UTD1) in combination with capecitabine for triple-negative breast cancer patients who did not achieve …
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CLINICAL_TRIALS research · 2023-02-21Clinical Trial Update: A Prospective, Phase II Trial Using ctDNA to Initiate Post-operation Boost Therapy After Adjuvant Chemotherapy in TNBC [Phase 2, Phase 3]
A prospective Phase II trial using circulating tumor DNA to guide post-operation boost therapy after adjuvant chemotherapy in triple-negativ…
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CLINICAL_TRIALS research · 2019-02-20Clinical Trial Update: Triple Negative Breast Cancer Trial [Phase 3]
A Phase 3 trial investigating triple-negative breast cancer is sponsored by the Institute of Cancer Research in the United Kingdom. The curr…
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CLINICAL_TRIALS research · 2018-05-31Clinical Trial Update: Triple-negative Breast Cancer: a New Perspective on Biomarkers
A completed clinical trial in Brazil assessing biomarkers in triple-negative breast cancer, presenting new perspectives on biomarker roles.
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CLINICAL_TRIALS research · 2017-11-28Clinical Trial Update: Clinical Study of Neoadjuvant Therapy With Apatinib and Paclitaxel in Local Advanced Triple-negative Breast Cancer [Phase 2]
Phase 2 study evaluating neoadjuvant Apatinib plus Paclitaxel in local advanced triple-negative breast cancer; status is currently UNKNOWN.
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CLINICAL_TRIALS research · 2017-11-07Clinical Trial Update: Clinical Study on Triple Negative Breast Cancer With Chinese Medicine
An update on a trial for triple-negative breast cancer using Traditional Chinese Medicine, with outcomes listed as progression-free survival…
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CLINICAL_TRIALS research · 2017-05-12Clinical Trial Update: Stereotactic Body Radiation Therapy Combined With Anti-PD-1 Antibody in Metastatic Triple Negative Breast Cancer [Phase 1]
Phase 1 study evaluating stereotactic body radiation therapy combined with an anti-PD-1 antibody in metastatic triple-negative breast cancer…
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CLINICAL_TRIALS research · 2017-04-19Clinical Trial Update: Comparative Study on Two Post-operative Adjuvant Chemotherapy Regimens for Treating Triple-negative Breast Cancer [Phase 3]
This document outlines a Phase 3 clinical trial comparing two postoperative adjuvant chemotherapy regimens for triple-negative breast cancer…
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CLINICAL_TRIALS research · 2016-12-06Clinical Trial Update: CAR-pNK Cell Immunotherapy in MUC1 Positive Relapsed or Refractory Solid Tumor [Phase 1, Phase 2]
A Phase 1/2 trial evaluating CAR-pNK cell immunotherapy for MUC1-positive relapsed or refractory solid tumors; current status is not provide…
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CLINICAL_TRIALS research · 2016-12-05Clinical Trial Update: Phase I/II Study of Anti-Mucin1 (MUC1) CAR T Cells for Patients With MUC1+ Advanced Refractory Solid Tumor [Phase 1, Phase 2]
Phase 1/2 trial evaluating Anti-Mucin1 (MUC1) CAR T cells in patients with MUC1-positive advanced refractory solid tumors across several can…
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CLINICAL_TRIALS research · 2016-10-18Clinical Trial Update: Study of Preoperative Chemotherapy for Early Triple Negative or HER2-positive Operable Breast Cancer [Phase 2]
Phase 2 clinical trial evaluating preoperative chemotherapy for patients with early triple-negative breast cancer or HER2-positive operable …
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CLINICAL_TRIALS research · 2016-08-08Clinical Trial Update: A Pilot Surveillance Study to Monitor Natural Killer Cells and Circulating Tumor Cells in Women With Previously Treated Non-metastatic Triple Negative Breast Cancer and Women With Previously Treated Non-metastatic Breast Cancer With a Confirmed BRCA Mutation.
A pilot study is ongoing to monitor natural killer cells and circulating tumor cells in women previously treated for non-metastatic triple-n…
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CLINICAL_TRIALS research · 2016-04-15Clinical Trial Update: Trial of Afatinib With Paclitaxel for Neoadjuvant Therapy of TNBC and Research of Biomarkers of Afatinib [Phase 2]
A Phase 2 clinical trial update evaluating afatinib in combination with paclitaxel as neoadjuvant therapy for triple-negative breast cancer,…
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CLINICAL_TRIALS research · 2016-02-22Clinical Trial Update: Neoadjuvant Chemotherapy Docetaxel With or Without SELUMETINIB in Patients With Triple Negative Breast Cancer [Phase 2]
A Phase 2 trial update evaluating neoadjuvant docetaxel with or without selumetinib in patients with triple-negative breast cancer.
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CLINICAL_TRIALS research · 2016-02-15Clinical Trial Update: Olaparib in Locally Advanced ER, PgR and HER2 Negative (Triple Negative) and in Locally Advanced Germline BRCA Mutation-positive Breast Cancer Patients [Phase 2]
Phase 2 trial update on olaparib (Lynparza) for locally advanced triple-negative breast cancer and locally advanced germline BRCA mutation–p…