Triple-negative Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-02-17Clinical Trial Update: The Intestinal Microbiome in Triple Negative Breast Cancer Treated with Immunotherapy
A clinical trial update on how the intestinal microbiome may influence response to immunotherapy in triple-negative breast cancer; the study…
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CLINICAL_TRIALS research · 2025-02-14Clinical Trial Update: Intensive Adjuvant Therapy for TNBC with BRCA Gene Mutation
Enrollment status update for a trial of intensive adjuvant therapy in triple-negative breast cancer patients with BRCA mutations (enrolling …
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CLINICAL_TRIALS research · 2025-02-13Clinical Trial Update: A Phase II Single-Arm Clinical Study to Explore the Efficacy and Safety of Hyperbaric Oxygen in the Neoadjuvant Treatment of Triple-Negative and HER2+ Breast Cancer Patients [NA]
A Phase II single-arm study is exploring the efficacy and safety of adding hyperbaric oxygen as neoadjuvant therapy for patients with triple…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Efficacy of Interleukin-2 in Triple Negative Breast Cancer [Phase 1, Phase 2]
This entry notes a planned Phase 1/2 clinical trial evaluating interleukin-2 for triple-negative breast cancer, with recruitment not yet sta…
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: QL1706 Plus Chemotherapy +/- Bevacizumab in 1L Treatment of R/mTNBC [Phase 2]
A Phase 2 trial is evaluating QL1706 in combination with chemotherapy, with or without bevacizumab, as first-line therapy for relapsed/metas…
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CLINICAL_TRIALS research · 2025-01-30Clinical Trial Update: Induction Therapy of PTX+BV Followed by Atezolizumab+Nab-PTX for PD-L1+ TNBC [Phase 2]
A Phase 2 clinical trial in metastatic PD-L1 positive triple-negative breast cancer evaluating induction therapy with paclitaxel plus bevaci…
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: Real-world Patient-reported Outcome of Sacituzumab Govitecan in Chinese Metastatic Triple-negative Breast Cancer
A clinical trial update describes evaluating Sacituzumab Govitecan in Chinese patients with metastatic triple-negative breast cancer, focusi…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Non-Inferiority Study on MRNA-lncRNA Model in Low-Risk Triple-Negative Breast Cancer Patients [Phase 3]
A Phase 3 non-inferiority trial evaluating an MRNA-lncRNA model for low-risk triple-negative breast cancer, currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-01-27Clinical Trial Update: BrAin Metastasis in tripLe Negateive Breast Cancer: IvoneScimab and Trop2 ADC [Phase 2]
Phase 2 clinical trial update for IvoneScimab in combination with a Trop2-targeted antibody-drug conjugate for brain metastases in patients …
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: Clinical Study of Camrelizumab Combined With TCb Versus TCb in Neoadjuvant Treatment of Triple-negative Breast Cancer [Phase 2]
Phase 2 trial evaluating camrelizumab in combination with TCb versus TCb alone as neoadjuvant therapy for triple-negative breast cancer. Rec…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: Home-Based Exercise Program During Neoadjuvant Treatment to Improve Fatigue and Quality of Life in Early HER2-Positive and Triple-Negative Breast Cancer Patients [NA]
This clinical trial update describes a home-based exercise program being studied during neoadjuvant therapy for early breast cancer patients…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: MRI Screening Versus SYMptom-directed Surveillance for Brain Metastases Among Patients with Triple Negative or HER2+ MBC [NA]
This clinical trial compares MRI screening to symptom-directed surveillance for brain metastases in patients with triple-negative or HER2-po…
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CLINICAL_TRIALS research · 2025-01-13Clinical Trial Update: Phase II Clinical Trial of PD-L1 in Combination with Vinorelbine + Cyclophosphamide + Capecitabine (VEX) Metronomic Chemotherapy with or Without Radiotherapy for Advanced Triple-negative Breast Cancer. [Phase 2]
Phase II clinical trial evaluating a PD-L1 inhibitor in combination with metronomic vinorelbine, cyclophosphamide, and capecitabine, with or…
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: A Clinical Study of 9MW2821 (and PD-1 Inhibitor) in Locally Advanced or Metastatic Triple-Negative Breast Cancer [Phase 2]
This document reports a Phase 2 clinical study of 9MW2821 in combination with a PD-1 inhibitor for locally advanced or metastatic triple-neg…
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CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: Omission of SLNB in Triple-negative and HER2-positive Breast Cancer Patients with RCR and PCR in the Breast After NAST [NA]
Clinical trial update on omitting sentinel lymph node biopsy in patients with triple-negative and HER2-positive breast cancer after neoadjuv…
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CLINICAL_TRIALS research · 2024-12-24Clinical Trial Update: A Phase II Clinical Study to Evaluate the Safety, Pharmacokinetic Profile, and Preliminary Efficacy of IMM2510 in Combination with Chemotherapy As First-line Treatment in Subjects with Non-small Cell Lung Cancer or Triple-negative Breast Cancer [Phase 2]
Phase II clinical study to evaluate safety, pharmacokinetics, and preliminary efficacy of IMM2510 in combination with chemotherapy as first-…
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: Paclitaxel + Carboplatin + Durvalumab With or Without Oleclumab for Previously Untreated Locally Recurrent Inoperable or Metastatic TNBC [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating paclitaxel and carboplatin with durvalumab, with or without oleclumab, as first-line therapy for previ…
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CLINICAL_TRIALS research · 2024-12-13Clinical Trial Update: All Trans Retinoic Acid Combined with Toripalimab+Chemotherapy for Locally Advanced Inoperable or Metastatic Triple Negative Breast Cancer：a Multi-center, Multi-cohort Phase II Trial [Phase 2]
A Phase II trial investigating the combination of all-trans retinoic acid with toripalimab and chemotherapy for locally advanced inoperable …
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CLINICAL_TRIALS research · 2024-12-12Clinical Trial Update: JAK1 Inhibitor Ivarmacitinib Reversing Immunotherapy Resistance in TNBC [Phase 2]
A Phase 2 clinical trial update reports a JAK1 inhibitor, ivarmacitinib, being studied to overcome immunotherapy resistance in triple-negati…
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: A Multicenter, Open-label Phase IIa Clinical Study to Evaluate the Efficacy and Safety of B1962 Injection in the Treatment of Advanced Malignant Solid Tumors [Phase 2]
This clinical trials update describes a multicenter, open-label Phase IIa study to evaluate the efficacy and safety of B1962 injections in a…
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CLINICAL_TRIALS research · 2024-12-02Clinical Trial Update: SBRT, Chemotherapy, and AK104 Neoadjuvant Therapy for Triple-negative Breast Cancer (TNBC) [Phase 2]
Phase 2 trial evaluating neoadjuvant therapy combining SBRT, chemotherapy, and AK104 for triple-negative breast cancer is currently recruiti…
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CLINICAL_TRIALS research · 2024-11-26Clinical Trial Update: Tislelizumab Combined with Nab-Paclitaxel for First-Line Treatment of Advanced Triple-Negative Breast Cancer with Bone Metastasis，an Exploratory, Single-Arm, Multicenter Phase II Clinical Study [Phase 2]
An exploratory Phase II trial evaluating tislelizumab plus nab-paclitaxel as first-line treatment for advanced triple-negative breast cancer…
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: Different Methods of Capecitabine in Patients With Non-PCR After Neoadjuvant Therapy for TNBC
A clinical trial evaluating different capecitabine regimens in patients with triple-negative breast cancer who did not achieve pathological …
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: De-escalation of Neoadjuvant Chemotherapy Regimens With Immunotherapy Among TNBC
A clinical trial is investigating de-escalation of neoadjuvant chemotherapy regimens combined with immunotherapy for triple-negative breast …
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Multiparametric MRI as a Non-Invasive Biomarker of the Tumor Microenviroment
A clinical trial investigating multiparametric MRI as a non-invasive biomarker of the tumor microenvironment in breast cancer has been suspe…