Triple-negative Breast Cancer
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: Feasibility Study of Adjuvant Enzalutamide for the Treatment of Early Stage AR (+) Triple Negative Breast Cancer [Phase 2]
A Phase 2 feasibility trial evaluating adjuvant enzalutamide for early-stage androgen receptor-positive triple-negative breast cancer; the s…
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CLINICAL_TRIALS research · 2025-06-19Clinical Trial Update: A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer [Phase 2]
This document reports a phase 2 clinical trial evaluating PCS6422 in combination with capecitabine for advanced or metastatic breast cancer,…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Comparing UTD2 Combined With Capecitabine to Capecitabine as Adjuvant Therapy for Non-pCR TNBC Patients [Phase 3]
Phase 3 clinical trial comparing UTD2 plus capecitabine to capecitabine alone as adjuvant therapy for patients with non-pCR triple-negative …
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
This update covers a completed Phase 1/2 clinical trial evaluating Tinengotinib (TT-00420) as both monotherapy and in combination therapy fo…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Real-world Study of Sacituzumab Govitecan Monotherapy or Combination Therapy in Recurrent or Metastatic HER2-negative Breast Cancer
Real-world clinical trial update on sacituzumab govitecan as monotherapy or in combination for recurrent or metastatic HER2-negative breast …
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Safety and Efficacy Analysis of an Antibody Associated With a Chemotherapy for Patients With a Triple Negative Metastatic Breast Cancer [Phase 3]
Phase 3 trial evaluating safety and efficacy of an antibody linked to chemotherapy for triple-negative metastatic breast cancer; trial is cu…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Immune-checkpoint Blockade After Partial Breast Irradiation by Pembrolizumab in Early TNBC [Phase 2]
This clinical trial update describes a Phase 2 study of pembrolizumab as immune-checkpoint blockade after partial breast irradiation in pati…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Arsenous Acid for Refractory Triple-Negative Breast Cancer [Phase 2]
A Phase 2 clinical trial is investigating arsenous acid for refractory triple-negative breast cancer and is currently recruiting.
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO [Phase 3]
A Phase 3 trial is evaluating whether an immune-oncology therapy given every three months after six months of standard administration is as …
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Clinical Study of QL1706 in Combination With Olaparib for the Treatment of Patients With Previously Treated Homologous Recombination Repair-Deficient Recurrent or Metastatic Triple-Negative Breast Cancer [Phase 2]
A Phase 2 clinical trial is evaluating QL1706 in combination with olaparib for previously treated homologous recombination repair-deficient …
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Exercise in Triple- Negative Breast Cancer [NA]
The document indicates a clinical trial investigating exercise in Triple-negative breast cancer is currently recruiting at Technical Univers…
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Sacituzumab Govitecan + Toripalimab as First - Line Therapy for Advanced Triple - Negative Breast Cancer and Biomarker Exploration
A study is evaluating first-line therapy with Sacituzumab Govitecan plus Toripalimab for advanced triple-negative breast cancer, with biomar…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Adjuvant Therapy With an Alpha-lactalbumin Vaccine in Triple-Negative Breast Cancer [EARLY_Phase 1]
An early-phase adjuvant trial of an alpha-lactalbumin vaccine in triple-negative breast cancer (Stage IIA-IIIC) is currently active but not …
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: Diagnostic Efficacy and Dosimetry of MNPR-101-DFO*-89Zr in Patients With Solid Tumors [Phase 1]
This ClinicalTrials.gov update describes a Phase 1 study evaluating MNPR-101-DFO*-89Zr as a diagnostic imaging agent for adults with various…
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: Evaluating Bemotuzumab to Improve the Efficacy of Neoadjuvant Chemotherapy for Triple-Negative Breast Cancer (TNBC) [NA]
A clinical trial evaluating bemotuzumab in combination with neoadjuvant chemotherapy for triple-negative breast cancer; the study status is …
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: A Study of Pembrolizumab and Cryoablation in People With Breast Cancer [Phase 1]
Phase 1 clinical trial evaluating pembrolizumab in combination with cryoablation for various breast cancers; currently recruiting.
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: Neoadjuvant Therapy With Ivonescimab Combined With Chemotherapy for Triple-Negative Breast Cancer [Phase 2]
A Phase 2 neoadjuvant trial is evaluating Ivonescimab in combination with chemotherapy for triple-negative breast cancer, and the study is c…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Immune PET and Proteomics for the Assessment of Response to Spatially Fractionated or Palliative Radiotherapy With or Without Immunotherapy [Phase 2]
Phase 2 clinical trial evaluating immune PET imaging and proteomics to assess response to spatially fractionated or palliative radiotherapy …
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Seviteronel in Combination With Chemotherapy in Androgen-receptor Positive Metastatic Triple-negative Breast Cancer [Phase 1, Phase 2]
This update describes a Phase 1/Phase 2 clinical trial evaluating seviteronel in combination with chemotherapy for androgen-receptor–positiv…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Evaluating and Monitoring Immune and Clinical Responses in Early-Stage Triple Negative Breast Cancer Undergoing Neoadjuvant Chemo-immunotherapy With Pembrolizumab
A clinical trial evaluating pembrolizumab with neoadjuvant chemo-immunotherapy for early-stage triple-negative breast cancer is currently re…
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CLINICAL_TRIALS research · 2025-05-09Clinical Trial Update: Study of Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC [Phase 3]
Phase 3 clinical trial evaluating Adagloxad Simolenin (OBI-822)/OBI-821 as adjuvant therapy for Globo H positive triple-negative breast canc…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Unresectable Locally Advanced or Recurrent Metastatic Triple-negative Breast Cancer [Phase 2]
A Phase 2 clinical trial is evaluating BL-B01D1 in combination with a PD-1 monoclonal antibody for unresectable locally advanced or recurren…
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CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: Neoadjuvant Chemotherapy With or Without GnRH Agonist for Premenopausal Triple-negative Early Breast Cancer Patients [Phase 2]
Phase 2 trial evaluating neoadjuvant chemotherapy with or without a GnRH agonist in premenopausal patients with triple-negative early breast…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: The Immune Effects of Fermented Wheat Germ Nutritional Supplementation in Patients With Advanced Solid Tumor Cancers Being Treated With Standard of Care Checkpoint Inhibitors [Phase 1]
Phase 1 trial update studying the immune effects of a fermented wheat germ extract added to standard checkpoint inhibitor therapy in patient…
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CLINICAL_TRIALS research · 2025-04-23Clinical Trial Update: OPTImaL:Optimisation of Treatment for Patients With Low Stage Triple-negative Breast Cancer With High Stromal Tumor-infiltrating Lymphocytes
This entry describes a clinical trial named OPTImaL investigating optimized treatment for patients with early-stage triple-negative breast c…