Transitional Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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EMA approval · 2026-08-19EMA Authorised: Opdivo (nivolumab) — Bristol-Myers Squibb Pharma EEIG
European Medicines Agency authorises Opdivo (nivolumab) for multiple cancer indications, including melanoma, non-small cell lung cancer, ren…
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EMA approval · 2026-07-21EMA Authorised: Tecentriq (atezolizumab) — Roche Registration GmbH
Roche's Tecentriq (atezolizumab) has been authorised by the EMA for multiple indications including transitional cell carcinoma, non-small ce…
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EMA approval · 2026-07-01EMA Authorised: Keytruda (pembrolizumab) — Merck Sharp & Dohme B.V.
EMA authorises Keytruda (pembrolizumab) for multiple cancer indications, including melanoma, Hodgkin disease, renal cell carcinoma, non-smal…
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EMA approval · 2026-04-28EMA Authorised: Tecentriq (atezolizumab) — Roche Registration GmbH
Authorised status for Tecentriq (atezolizumab) by Roche Registration GmbH across multiple cancer indications in the European market.
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract [Phase 3]
A Phase 3 clinical trial evaluating Vepugratinib (LY3866288) in participants with urinary tract cancers, including transitional cell carcino…
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EMA approval · 2026-03-30EMA Authorised: Tecentriq (atezolizumab) — Roche Registration GmbH
The European Medicines Agency authorized Tecentriq (atezolizumab) by Roche Registration GmbH for multiple cancer indications, including non-…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Ixazomib Citrate With Gemcitabine Hydrochloride and Doxorubicin Hydrochloride in Treating Patients With Urothelial Cancer That is Metastatic or Cannot Be Removed by Surgery [Phase 1, Phase 2]
A Phase 1/2 trial evaluating ixazomib citrate with gemcitabine and doxorubicin for metastatic or unresectable urothelial carcinoma; the stud…
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EMA approval · 2025-07-16EMA Authorised: Javlor (vinflunine) — Pierre Fabre Medicament
The European Medicines Agency authorised Javlor (vinflunine) from Pierre Fabre Medicament for transitional cell carcinoma of the urothelium …
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CLINICAL_TRIALS trial_result · 2023-11-24Clinical Trial Update: First-line Everolimus +/- Paclitaxel for Cisplatin-ineligible Patients With Advanced Urothelial Carcinoma [Phase 2]
Phase 2 trial evaluating first-line everolimus with or without paclitaxel in cisplatin-ineligible advanced urothelial carcinoma was terminat…
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CLINICAL_TRIALS trial_result · 2022-10-05Clinical Trial Update: Paclitaxel and Pembrolizumab in Treating Patients With Refractory Metastatic Urothelial Cancer [Phase 2]
Phase 2 trial evaluating paclitaxel and pembrolizumab in refractory metastatic urothelial cancer (transitional cell carcinoma) has completed…
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CLINICAL_TRIALS trial_result · 2022-01-13Clinical Trial Update: Nab-paclitaxel Plus Gemcitabine as First-line Therapy for Cisplatin-ineligible or Cisplatin-incurable Advanced Urothelial Carcinoma [Phase 2]
Phase 2 trial of nab-paclitaxel plus gemcitabine as first-line therapy for cisplatin-ineligible or cisplatin-incurable advanced urothelial c…
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CLINICAL_TRIALS trial_result · 2021-11-03Clinical Trial Update: Tailored ImmunoTherapy Approach With Nivolumab in Subjects With Metastatic or Advanced Transitional Cell Carcinoma [Phase 2]
Phase 2 trial evaluating a tailored immunotherapy approach with nivolumab in metastatic or advanced transitional cell carcinoma.
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CLINICAL_TRIALS trial_result · 2021-07-08Clinical Trial Update: Vaccine Therapy in Treating Patients With Transitional Cell Carcinomas [Phase 1]
Phase 1 trial update of a vaccine therapy in transitional cell carcinoma was completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-05-07Clinical Trial Update: Preoperative Bintrafusp Alfa in Operable Urothelial Carcinoma of the Bladder [Phase 2]
A Phase 2 clinical trial update evaluating preoperative Bintrafusp Alfa in operable urothelial carcinoma of the bladder is in progress.
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CLINICAL_TRIALS withdrawal · 2020-05-07Clinical Trial Update: Efficacy and Safety of UGN-101 in Recurrent Patients [Phase 3]
Phase 3 trial of UGN-101 for recurrent carcinoma variants has been withdrawn.
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CLINICAL_TRIALS trial_result · 2019-04-11Clinical Trial Update: Alisertib in Chemotherapy-pretreated Urothelial Cancer [Phase 2]
Phase 2 trial of alisertib in chemotherapy-pretreated urothelial/bladder cancer has completed.
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CLINICAL_TRIALS trial_result · 2018-12-04Clinical Trial Update: Treatment of Locally Advanced or Metastatic Transitional Cell Carcinoma With Cabazitaxel [Phase 2, Phase 3]
A completed clinical trial update evaluating cabazitaxel for locally advanced or metastatic transitional cell carcinoma across Phase 2 and P…
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CLINICAL_TRIALS trial_result · 2017-09-28Clinical Trial Update: Four Cycles Versus Six Cycles of Cisplatin-based Chemotherapy in Metastatic Urothelial Carcinoma [Phase 3]
A Phase 3 trial comparing four vs six cycles of cisplatin-based chemotherapy in metastatic urothelial carcinoma is ongoing/unknown status.
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CLINICAL_TRIALS trial_result · 2017-04-27Clinical Trial Update: Dual Energy CT vs Standard Triple Phase CT-A Randomised Control Trial [NA]
This entry notes a completed randomized trial comparing Dual Energy CT to Standard Triple Phase CT Angiography. The study involved patients …
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CLINICAL_TRIALS trial_result · 2017-01-09Clinical Trial Update: A Phase 1 Study of Mixed Bacteria Vaccine (MBV) in Patients With Tumors Expressing NY-ESO-1 Antigen [Phase 1]
Phase 1 study of a mixed bacteria vaccine (MBV) targeting NY-ESO-1 tissue expression in various tumors; completed with posted results.
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CLINICAL_TRIALS research · 2016-04-28Clinical Trial Update: Intravesically Heated Thermo-chemotherapy With Mitomycin-C Prior to TURBT [NA]
This clinical trial update describes a study evaluating intravesically heated thermo-chemotherapy with mitomycin-C prior to TURBT for transi…
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CLINICAL_TRIALS research · 2015-12-18Clinical Trial Update: Feasibility Evaluation of Magnetic Resonance Imaging and Positron Emission Tomography for Bladder Cancer Diagnosis and Staging
A completed feasibility study evaluating the use of MRI and PET imaging for the diagnosis and staging of bladder cancer, with no treatment d…
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CLINICAL_TRIALS trial_result · 2015-10-09Clinical Trial Update: Phase II Study of Brivanib (BMS-582664) to Treat Multiple Tumor Types [Phase 2]
Phase II clinical trial of Brivanib (BMS-582664) across multiple tumor types has completed.
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CLINICAL_TRIALS trial_result · 2014-10-22Clinical Trial Update: Multi-center Study to Evaluate the Efficacy and Safety of Maintenance Therapy With Valrubicin Versus no Maintenance, in Subjects Treated With Valrubicin Induction for Carcinoma in Situ (CIS) of the Bladder [Phase 3]
A Phase 3 trial evaluating maintenance valrubicin versus no maintenance after valrubicin induction in bladder carcinoma in situ; study termi…
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CLINICAL_TRIALS trial_result · 2014-06-04Clinical Trial Update: Randomized Study of Docetaxel +/- Vandetanib in Metastatic TCC [Phase 2]
Phase 2 randomized study assessing docetaxel with or without vandetanib in metastatic transitional cell carcinoma of the bladder; study comp…