Tobacco Use Disorder
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CLINICAL_TRIALS trial_result · 2024-09-27Clinical Trial Update: A Study to Evaluate Changes in Smokers Using An Oral Tobacco-Derived Nicotine Product [NA]
This update reports the completion of a study evaluating changes in smokers using an oral tobacco-derived nicotine product. Results were pos…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Checking Smoking Status as a Routine Vital Sign: A Cluster-Randomized Trial of Its Effect on Cessation Counseling [NA]
A cluster-randomized trial evaluated whether routinely checking smoking status as a vital sign influences cessation counseling; the study is…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Proof-of-concept RCT of Version 3.0 of the Smoking Cessation Smartphone App "Smiling Instead of Smoking" (SiS) [NA]
This document reports results from a proof-of-concept randomized controlled trial evaluating version 3.0 of the Smiling Instead of Smoking (…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Varenicline OTC Trial on Efficacy and Safety [Phase 4]
Phase 4 clinical trial update evaluating the efficacy and safety of an over-the-counter varenicline formulation for tobacco use disorder, wi…
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FDA approval · 2024-09-06FDA Approved: NICORETTE — Supplemental Application (Haleon US Holdings LLC)
The FDA approved a supplemental application for Nicorette (nicotine polacrilex) submitted by Haleon US Holdings LLC.
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: 12-Month Efficacy of Exercise and Cytisinicline for Tobacco Abstinence [Phase 4]
Phase 4 trial update assessing whether combining exercise with cytisinicline yields 12-month smoking abstinence. The study is currently not …
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CLINICAL_TRIALS trial_result · 2024-08-30Clinical Trial Update: A Trial of Directly Observed and Long-term Varenicline [Phase 4]
Phase 4 trial evaluating directly observed and long-term varenicline for tobacco use disorder, including participants with opioid use disord…
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CLINICAL_TRIALS withdrawal · 2024-08-27Clinical Trial Update: Varenicline for the Treatment of Cannabis and Tobacco Use Disorders in Veterans [Phase 2]
A Phase 2 clinical trial evaluating varenicline for tobacco use disorder and cannabis use disorder in veterans has been withdrawn.
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CLINICAL_TRIALS research · 2024-08-26Clinical Trial Update: Testing ANSOS for Efficacy in Multi-Tribal Urban Communities [NA]
Clinical trial update shows ANSOS is being studied for efficacy in smokeless tobacco cessation in multi-tribal urban communities. The study …
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Cue Effects in Human Addiction: Pavlovian to Instrumental Transfer
Charité University Berlin is conducting a clinical study on cue effects in human addiction (Pavlovian to instrumental transfer) that is curr…
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: Impact of Very Low Nicotine Content Cigarettes in a Complex Marketplace [Phase 3]
Phase 3 study evaluating the impact of very low nicotine content cigarettes in a complex marketplace; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: Measuring Neuroadaptations in Response to Very Low Nicotine Content Cigarettes [NA]
A completed clinical trial from Milton S. Hershey Medical Center assessing neuroadaptive brain changes in response to cigarettes with very l…
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CLINICAL_TRIALS research · 2024-08-19Clinical Trial Update: Mobile Phone-Based Smoking-Cessation Intervention for Chronic Patients [NA]
Beijing Normal University is sponsoring a clinical trial evaluating a mobile phone-based intervention to aid smoking cessation; the trial st…
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CLINICAL_TRIALS research · 2024-08-14Clinical Trial Update: Theta-burst Repetitive Transcranial Magnetic Stimulation (TBS) of the Right Inferior Frontal Gyrus for Treatment of Nicotine Dependence [NA]
A clinical trial evaluating theta-burst repetitive transcranial magnetic stimulation of the right inferior frontal gyrus as a treatment for …
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Pharmacokinetics and Comparative Bioavailability of Nicotine From Two Variants of NP2, NP2-4mg and NP2-6mg, Compared to Nicotine Lozenge 4mg (Loz-4mg) and Nicotine Gum 4mg (Gum-4mg) [NA]
A completed pharmacokinetic study comparing nicotine absorption from two NP2 variants (NP2-4mg and NP2-6mg) with nicotine lozenge 4mg and ni…
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CLINICAL_TRIALS research · 2024-08-12Clinical Trial Update: Smoking Cessation Intervention for American Indian Women Experiencing Intimate Partner Violence [NA]
A clinical trial sponsored by Black Hills Center for American Indian Health is recruiting to evaluate a smoking cessation intervention for A…
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Volitional Dysfunction in Self-control Failures and Addictive Behaviors
A completed clinical trial from Technische Universität Dresden investigating volitional dysfunction in self-control failures related to addi…
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: Smoking Cessation Behavioral Treatment Study [NA]
Ongoing clinical trial (NCT03948893) evaluating behavioral treatment for tobacco use disorder; currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: Brain Imaging in Tobacco Smokers During a Quit Attempt [Phase 1]
This clinical trial update summarizes Phase 1 results on brain imaging in tobacco smokers attempting to quit, conducted by Johns Hopkins Uni…
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CLINICAL_TRIALS trial_result · 2024-08-05Clinical Trial Update: Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettes [Phase 2]
A Phase 2 clinical trial by Yale University evaluated how different e-liquid flavors affect nicotine perception and self-administration via …
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CLINICAL_TRIALS trial_result · 2024-08-05Clinical Trial Update: Smoking Reduction In Gravid Substance Use Disorders [NA]
The trial evaluating smoking reduction in pregnant individuals with tobacco use disorders has completed and posted results.
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Research and Innovation to Stop E-cigarette/Vaping in Young Adults [Phase 4]
Phase 4 trial completion and results posting for a study led by Ohio State University addressing nicotine dependence and e-cigarette use amo…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: Assessing the Integration of Tobacco Cessation Treatment Into Lung Cancer Screening (LCS) [Phase 4]
Phase 4 trial evaluating integration of tobacco cessation treatment into lung cancer screening; results were posted on 2024-07-23.
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FDA approval · 2024-07-23FDA Approved: VARENICLINE — Original Application (Nivagen Pharmaceuticals Inc.)
FDA approved the generic varenicline product from Nivagen Pharmaceuticals Inc. under an Original Application (ANDA 217115) for smoking cessa…
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CLINICAL_TRIALS research · 2024-07-19Clinical Trial Update: Brief Behavioural Economic Intervention for Smoking Cessation [NA]
An ongoing clinical trial from The University of Hong Kong is evaluating a brief behavioral economic intervention to aid smoking cessation. …