Tobacco Use Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: A Study to Evaluate Changes in Smokers Using Oral Tobacco-derived Nicotine Products. [NA]
A clinical trial evaluating changes in smokers using oral tobacco-derived nicotine products has completed and posted results.
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CLINICAL_TRIALS trial_result · 2024-11-21Clinical Trial Update: Twitter-enabled Mobile Messaging for Smoking Relapse Prevention (Tweet2Quit) [Phase 2]
Phase 2 clinical trial of Tweet2Quit, a Twitter-enabled mobile messaging program, completed with results posted evaluating its effectiveness…
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: Trial for Harm Reduction With Incentives & Vaping E-cigarettes [NA]
Brown University conducted a completed clinical trial evaluating incentive-based harm reduction using electronic cigarettes for obesity and …
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: Personalized Feedback for Distress Intolerant Smokers [NA]
This completed clinical trial from the University of Houston studied personalized feedback for distress intolerant smokers. Results were pos…
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: Gain-framed Messages and NRT for Lung Cancer Screening Patients [Phase 2]
A Phase 2 trial evaluated gain-framed messages plus nicotine replacement therapy to promote smoking cessation among individuals undergoing l…
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: A Study of Cytisinicline for Smoking Cessation in Adult Smokers [Phase 3]
A Phase 3 trial evaluating cytisinicline for smoking cessation in adult smokers has completed with results posted in November 2024.
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: Development and Pilot Testing of the Sense2Quit App [NA]
This update reports development and pilot testing of the Sense2Quit app, a digital intervention for smoking cessation, with results from a c…
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CLINICAL_TRIALS trial_result · 2024-11-04Clinical Trial Update: Deep rTMS and Varenicline for Smoking Cessation [NA]
The clinical trial evaluating deep rTMS in combination with varenicline for smoking cessation has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: E-cigarettes as a Harm Reduction Strategy [NA]
A trial sponsored by Prisma Health-Upstate evaluated whether e-cigarettes could serve as a harm-reduction strategy for smokers; the study st…
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: Smokers' Response to Nicotine Dependence Genotyping [NA]
This clinical trial update notes that a study on smokers' response to nicotine dependence genotyping has completed and posted results.
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: Smoking Prevention Through Social Connections Among Adolescents - ASPIRE [NA]
ASPIRE is a completed adolescent smoking-prevention trial evaluating whether social connections can reduce tobacco use behavior; results wer…
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: Enhancing Equity in Smoke-free Housing [NA]
A Harvard School of Public Health clinical trial, Enhancing Equity in Smoke-free Housing, is currently enrolling by invitation to study toba…
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Interventions to Help More Low-income Smokers Quit [NA]
This entry reports results from a completed clinical trial evaluating interventions to help low-income smokers quit smoking.
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: Twitter-enabled Mobile Messaging for Smoking Relapse Prevention [NA]
A completed clinical trial evaluated Twitter-enabled mobile messaging to prevent smoking relapse; results were posted on 2024-10-09.
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Promoting Smoking Cessation in Lung Cancer Screening Through Proactive Treatment [NA]
A VA-sponsored study evaluating proactive treatment to promote smoking cessation in individuals undergoing lung cancer screening has complet…
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CLINICAL_TRIALS trial_result · 2024-10-02Clinical Trial Update: Effects of an Oral Nicotine Product in Smokeless Tobacco Users [NA]
A completed clinical trial evaluated an oral nicotine product in smokeless tobacco users, sponsored by Virginia Commonwealth University.
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CLINICAL_TRIALS trial_result · 2024-09-27Clinical Trial Update: A Study to Evaluate Changes in Smokers Using An Oral Tobacco-Derived Nicotine Product [NA]
This update reports the completion of a study evaluating changes in smokers using an oral tobacco-derived nicotine product. Results were pos…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Checking Smoking Status as a Routine Vital Sign: A Cluster-Randomized Trial of Its Effect on Cessation Counseling [NA]
A cluster-randomized trial evaluated whether routinely checking smoking status as a vital sign influences cessation counseling; the study is…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Proof-of-concept RCT of Version 3.0 of the Smoking Cessation Smartphone App "Smiling Instead of Smoking" (SiS) [NA]
This document reports results from a proof-of-concept randomized controlled trial evaluating version 3.0 of the Smiling Instead of Smoking (…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Varenicline OTC Trial on Efficacy and Safety [Phase 4]
Phase 4 clinical trial update evaluating the efficacy and safety of an over-the-counter varenicline formulation for tobacco use disorder, wi…
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: 12-Month Efficacy of Exercise and Cytisinicline for Tobacco Abstinence [Phase 4]
Phase 4 trial update assessing whether combining exercise with cytisinicline yields 12-month smoking abstinence. The study is currently not …
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CLINICAL_TRIALS trial_result · 2024-08-30Clinical Trial Update: A Trial of Directly Observed and Long-term Varenicline [Phase 4]
Phase 4 trial evaluating directly observed and long-term varenicline for tobacco use disorder, including participants with opioid use disord…
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: Impact of Very Low Nicotine Content Cigarettes in a Complex Marketplace [Phase 3]
Phase 3 study evaluating the impact of very low nicotine content cigarettes in a complex marketplace; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: Measuring Neuroadaptations in Response to Very Low Nicotine Content Cigarettes [NA]
A completed clinical trial from Milton S. Hershey Medical Center assessing neuroadaptive brain changes in response to cigarettes with very l…
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Pharmacokinetics and Comparative Bioavailability of Nicotine From Two Variants of NP2, NP2-4mg and NP2-6mg, Compared to Nicotine Lozenge 4mg (Loz-4mg) and Nicotine Gum 4mg (Gum-4mg) [NA]
A completed pharmacokinetic study comparing nicotine absorption from two NP2 variants (NP2-4mg and NP2-6mg) with nicotine lozenge 4mg and ni…