Tobacco Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-07Clinical Trial Results: Testing the Effect of ENDS Flavors on Neurotransmission [NA]
Completed clinical trial assessing how ENDS flavors affect neurotransmission in tobacco dependence; results posted.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Assessment of Biomarkers in Children to Help Parents Quit Tobacco [NA]
ClinicalTrials.gov entry for a Massachusetts General Hospital study assessing biomarkers in children to help parents quit tobacco; the trial…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Cannabidiol for Reducing Cigarette Use [Phase 2]
Phase 2 clinical trial investigating cannabidiol to reduce cigarette use in adults with tobacco use disorder; recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Cytisine vs Nicotine Replacement Therapy [NA]
This entry notes an ongoing clinical trial comparing cytisine to nicotine replacement therapy for tobacco dependence, with enrollment by inv…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Early Withdrawal Exposure and Negative Affect Withdrawal (NAW) Regulation Training for Smoking Cessation [Phase 3]
Phase 3 clinical trial update evaluating training to regulate withdrawal and negative affect withdrawal for smoking cessation; the study is …
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CLINICAL_TRIALS trial_result · 2026-02-02Clinical Trial Update: C-Raven, a Virtual Tobacco Cessation Intervention in the Community [Phase 4]
A Phase 4 trial of C-Raven, a virtual tobacco cessation intervention in community settings, has completed.
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Effect of Yoga on Reducing Craving in Tobacco Dependent Individuals [NA]
A University of Pittsburgh-sponsored clinical trial is investigating whether yoga can reduce cravings in individuals with tobacco dependence…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Use of Nicotine Pouches Among Daily Smokers [NA]
A clinical trial is evaluating the use of nicotine pouches among daily smokers with tobacco dependence; the study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Identifying Effective Treatment for Veterans Unwilling to Quit Smoking [NA]
VA Office of Research and Development completed a clinical trial evaluating treatments for tobacco dependence in veterans who are unwilling …
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Testing the Effect of ENDS Flavors on Neurotransmission [NA]
Clinical trial update noting the completion of a study examining how electronic nicotine delivery system flavors influence neurotransmission…
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CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: Low Nicotine Cigarettes Plus Electronic Cigarettes [NA]
A completed clinical trial from Milton S. Hershey Medical Center evaluated using low-nicotine cigarettes in combination with electronic ciga…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: Testing C-Raven, a Virtual Tobacco Cessation Intervention, in the Community [Phase 4]
Phase 4 trial evaluating C-Raven, a virtual tobacco cessation intervention, completed in community settings and results were posted on 2025-…
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CLINICAL_TRIALS trial_result · 2025-06-22Clinical Trial Update: Establishing the Effect of Flavor on the Addictive Potential of Electronic Cigarettes [NA]
A completed clinical trial evaluating whether flavorings in electronic cigarettes influence their addictive potential; results have been pos…
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Evaluation of Tobacco Treatment Strategies for Inpatient Psychiatry [NA]
A completed clinical trial evaluating tobacco treatment strategies for inpatient psychiatry, with results posted in 2025.
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CLINICAL_TRIALS trial_result · 2025-05-28Clinical Trial Update: Interactive Mobile Doctor (iMD) to Promote Tobacco Cessation Among Cancer Patients [NA]
A completed clinical trial evaluating the Interactive Mobile Doctor (iMD) tool designed to promote tobacco cessation among cancer patients.
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: Chatbot for Online Support Groups to Treat Tobacco Addiction [NA]
Clinical trial update on a chatbot-based online support group to treat tobacco addiction. The study status is Not Yet Recruiting.
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: Cooling Agent Pilot Among Adult Menthol Smokers [NA]
This document reports the completion of a pilot clinical trial evaluating a cooling agent for adult menthol cigarette smokers to address tob…
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: Does Switching to Nicotine Containing Electronic Cigarettes Reduce Health Risk Markers [NA]
A completed clinical trial evaluating whether switching to nicotine-containing electronic cigarettes reduces health risk markers in adults w…
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: CO Monitoring for Tobacco Cessation in Quitlines [Phase 1, Phase 2]
A clinical trial evaluated carbon monoxide monitoring as an aid for tobacco cessation in quitlines across Phase 1 and Phase 2, with results …
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CLINICAL_TRIALS trial_result · 2024-09-26Clinical Trial Update: Cigarette Smoking in Smokers With and Without Schizophrenia [NA]
A completed clinical trial compared cigarette smoking in smokers with schizophrenia to those without schizophrenia; results have been posted…
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: Varenicline for Co-occurring Cannabis and Tobacco Use [Phase 4]
Phase 4 clinical trial update evaluating varenicline for co-occurring cannabis and tobacco dependence has been completed, with results poste…
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CLINICAL_TRIALS withdrawal · 2024-05-08Clinical Trial Update: Equitable Smoking Relapse Prevention [NA]
The clinical trial Equitable Smoking Relapse Prevention (NCT05625685) related to tobacco use disorder has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2023-12-01Clinical Trial Update: UW Withdraw From Tobacco Study [Phase 2]
The University of Wisconsin, Madison withdrew from a Phase 2 tobacco dependence trial; the study is listed as completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-12-22Clinical Trial Update: Novel Determinants and Measures of Smokeless Tobacco Use: Study 1
Clinical trial update on novel determinants and measures of smokeless tobacco use (Study 1) completed; results posted.
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FDA approval · 2022-12-13FDA Approved: BUPROPION — Supplemental Application (Zydus Pharmaceuticals USA Inc.)
FDA approved a supplemental application for Bupropion submitted by Zydus Pharmaceuticals USA Inc.