Thyroid Eye Disease
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Sign up freeTop drugs studied for this disease
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FDA approval · 2023-04-13FDA Approved: TEPEZZA — Supplemental Application (Horizon Therapeutics USA, Inc.)
FDA overview of a supplemental application for TEPEZZA (teprotumumab) by Horizon Therapeutics USA, Inc.; the submission status is AP.
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FDA approval · 2022-12-06FDA Approved: TEPEZZA — Supplemental Application (Horizon Therapeutics USA, Inc.)
The FDA approved a supplemental application for TEPEZZA (teprotumumab) submitted by Horizon Therapeutics USA, Inc.
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CLINICAL_TRIALS withdrawal · 2022-01-10Clinical Trial Update: The Effect of a New Antioxidant Combination (ASTED) on Moderate to Severe Thyroid Eye Disease [Phase 2, Phase 3]
A Phase 2/3 trial evaluating an antioxidant combination (ASTED) for moderate to severe Thyroid Eye Disease was withdrawn.
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CLINICAL_TRIALS trial_result · 2021-10-04Clinical Trial Update: Hyaluronic Acid Gels for Upper Lid Retraction in Active Stage Thyroid Eye Disease [Phase 4]
Phase 4 trial update on hyaluronic acid gels for upper lid retraction in active stage thyroid eye disease; study terminated.
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CLINICAL_TRIALS trial_result · 2020-07-31Clinical Trial Update: Celecoxib for Thyroid Eye Disease [Phase 2]
Phase 2 trial of celecoxib for Thyroid Eye Disease was terminated; results were posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-03-10Clinical Trial Update: Treatment of Graves' Orbitopathy (Thyroid Eye Disease) to Reduce Proptosis With Teprotumumab Infusions in a Randomized, Placebo-Controlled, Clinical Study [Phase 3]
A Phase 3 randomized, placebo-controlled trial of teprotumumab infusions in Graves' orbitopathy (thyroid eye disease) completed with results…
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FDA approval · 2020-01-21FDA Approved: TEPEZZA — Original Application (Horizon Therapeutics USA, Inc.)
The FDA approved TEPEZZA (teprotumumab) from Horizon Therapeutics USA, Inc. under an original biologics license application. This marks the …
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CLINICAL_TRIALS withdrawal · 2018-05-15Clinical Trial Update: The Secondary Beneficial Effects of Prostaglandin Analog Treatment in Thyroid Eye Disease Patients. [Phase 4]
Phase 4 trial investigating secondary benefits of a prostaglandin analog in Thyroid Eye Disease was withdrawn; the study also referenced ocu…
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CLINICAL_TRIALS trial_result · 2018-02-19Clinical Trial Update: Treatment of Soft Tissue Expansion in Inactive Thyroid Eye Disease Patients Using Drops of Prostaglandin Analogues [Phase 3]
Phase 3 trial assessing prostaglandin analogue drops for treating soft tissue expansion in inactive thyroid eye disease (thyroid-associated …
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CLINICAL_TRIALS trial_result · 2017-08-30Clinical Trial Update: Teprotumumab (RV 001) Treatment in Patients With Active Thyroid Eye Disease [Phase 2]
Phase 2 trial of teprotumumab in active thyroid eye disease completed; results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-04-06Clinical Trial Update: Disappearance of Graves' Orbitopathy
A completed clinical trial by the University of Pisa in Thyroid Eye Disease reports disappearance of Graves' ophthalmopathy.
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CLINICAL_TRIALS trial_result · 2016-01-20Clinical Trial Update: Tocilizumab Treatment in Graves´ Ophthalmopathy (Graves´ Orbitopathy or Thyroid Eye Disease) [Phase 3]
Phase 3 trial assessing tocilizumab for Graves' ophthalmopathy (thyroid eye disease) has completed.
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CLINICAL_TRIALS trial_result · 2015-03-26Clinical Trial Update: Pilot Study to Determine Safety and Efficacy of Orbital Injections of LIPO-102 in Patients With Symptomatic Exophthalmos Associated With Thyroid-related Eye Disease (TED) [Phase 2]
Phase 2 pilot study evaluating the safety and efficacy of orbital injections of LIPO-102 for exophthalmos in thyroid eye disease has complet…
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CLINICAL_TRIALS trial_result · 2015-03-02Clinical Trial Update: Twenty-four Hour Intraocular Pressure Patterns in Patients With Uncontrolled Thyroid Eye Disease [NA]
This clinical trial update reports completed results on 24-hour intraocular pressure patterns in patients with uncontrolled thyroid eye dise…
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CLINICAL_TRIALS trial_result · 2012-09-24Clinical Trial Update: Reliability of Hertel Exophthalmometer Measurements
A completed trial evaluating the reliability and standardization of Hertel exophthalmometer measurements for assessing exophthalmos.
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CLINICAL_TRIALS research · 2007-02-27Clinical Trial Update: Effect of Percutaneous Botulinum Toxin A Injection on Natural Course of Upper Lid Retraction in Thyroid Eye Disease [Phase 2, Phase 3]
A Phase 2/3 clinical trial is evaluating percutaneous botulinum toxin A injection to address upper lid retraction in thyroid eye disease. Th…