Thyroid Cancer
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CLINICAL_TRIALS research · 2024-08-06Clinical Trial Update: Preoperative Hemogram Parameters and BRAF Molecular Test Detected by Bethesda 3 Cytology.
A recruiting trial from Saglik Bilimleri Universitesi studies preoperative hemogram parameters and BRAF V600E molecular testing detected by …
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CLINICAL_TRIALS research · 2024-08-02Clinical Trial Update: RET Inhibitor for Neoadjuvant Therapy in Locally Advanced RET-altered Thyroid Cancer
A clinical trial is evaluating a RET inhibitor as neoadjuvant therapy for locally advanced RET-altered thyroid cancer; recruitment is ongoin…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: AIM1: Adequate Selection of Patients for Thyroid Biopsy: Evaluation of a Shared Decision Making Conversation Aid [NA]
A completed clinical trial evaluated a shared decision-making conversation aid to improve patient selection for thyroid biopsy; results have…
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Multimodality US Based on Angio Planewave Ultrasensitive Imaging and Shear Wave Elastography to Evaluate the Malignancy Risk Value of Thyroid Nodules
This entry describes a clinical study evaluating a multimodal ultrasound approach (Angio Planewave Ultrasensitive Imaging and Shear Wave Ela…
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CLINICAL_TRIALS trial_result · 2024-07-11Clinical Trial Update: Phase II Study of Tipifarnib in Squamous Head and Neck Cancer With HRAS Mutations [Phase 2]
This entry reports the completion of a Phase II trial of tipifarnib in HRAS-mutant squamous cell carcinoma of the head and neck, with result…
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CLINICAL_TRIALS research · 2024-07-09Clinical Trial Update: A Prospective Trial Comparing Transoral Endoscopic Thyroidectomy Vestibular Approach (TOETVA) and Conventional Open Thyroidectomy [NA]
A prospective trial comparing Transoral Endoscopic Thyroidectomy Vestibular Approach (TOETVA) with conventional open thyroidectomy is curren…
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: Parathyroid Vascularization During Total Thyroidectomy Using Indocyanine Green Angiography
This clinical trial evaluated parathyroid vascularization during total thyroidectomy using indocyanine green angiography; the study status w…
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CLINICAL_TRIALS trial_result · 2024-06-14Clinical Trial Update: Energy Metabolism in Thyroidectomized Patients [Phase 2]
Phase 2 clinical trial update on energy metabolism in thyroidectomized patients. The study has completed and posted results (June 14, 2024) …
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FDA label_change · 2024-06-12FDA Approved: RETEVMO — Supplemental Application (Eli Lilly and Company)
FDA approved a supplemental application for RETEVMO (selpercatinib) from Eli Lilly, indicating an update to the drug’s labeling. The action …
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CLINICAL_TRIALS research · 2024-06-05Clinical Trial Update: I-124 PET/CT Imaging and Dosimetry for RAI-Naïve or Refractory Thyroid Cancer
This clinical trial update describes a study evaluating I-124 PET/CT imaging and dosimetry in thyroid cancer patients, including those who a…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: The Effect of the Number of Central Lymph Nodes on Changes in Parathyroid Function
This clinical trial update reports on a completed study evaluating how the number of central lymph nodes affects parathyroid function in thy…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: The Effect of the Application of Head Mounted Magnifying Glasses on Postoperative PTH Changes in Thyroid Surgery
A completed clinical trial evaluating whether using head-mounted magnifying glasses during thyroid cancer surgery affects postoperative para…
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CLINICAL_TRIALS research · 2024-05-28Clinical Trial Update: Study on the Mechanism of Ganoderma Lucidum Spore Powder in the Treatment of Depression [NA]
Completed clinical trial examining the mechanism of Ganoderma lucidum spore powder in the treatment of depression. The study lists depressio…
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CLINICAL_TRIALS research · 2024-05-23Clinical Trial Update: Influencing Factors and Prediction Model of False-negative Central Lymph Nodes in Thyroid Cancer Patients
The update analyzes factors associated with false-negative results in central lymph node assessment for thyroid cancer and introduces a pred…
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: Nivolumab Plus Ipilimumab in Thyroid Cancer [Phase 2]
A Phase 2 trial evaluating the combination of nivolumab and ipilimumab in thyroid cancer has completed and posted results.
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: Transoral Endoscopic Thyroidectomy by Vestibular Approach (TOETVA) [NA]
Clinical trial update on Transoral Endoscopic Thyroidectomy by Vestibular Approach (TOETVA) for thyroid diseases, including thyroid cancer; …
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CLINICAL_TRIALS research · 2024-05-13Clinical Trial Update: Mapping Patient Decision-making in Thyroid Cancer [NA]
Clinical trial update on mapping patient decision-making in thyroid cancer; the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: Risk of Malignancy in Endemic Long Standing Nodular Goitres: a Prospective Cohort Study
This document reports results from a prospective cohort study assessing the risk of thyroid cancer in individuals with long-standing endemic…
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CLINICAL_TRIALS trial_result · 2024-04-26Clinical Trial Update: Study of TT-00420 (Tinengotinib) Tablet as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1 and Phase 2 trials evaluated tinengotinib (TT-00420) as a monotherapy and in combination therapy for patients with advanced solid tu…
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FDA approval · 2024-04-10FDA Approved: RETEVMO — Original Application (Eli Lilly and Company)
The FDA approved the original application for selpercatinib (RETEVMO) from Eli Lilly and Company. It is approved for RET fusion-positive non…
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CLINICAL_TRIALS research · 2024-04-03Clinical Trial Update: The Effect of Surgeon Emotional Support on Treatment Choice for Low-risk Thyroid Cancer [NA]
A completed clinical trial examining whether surgeon emotional support influences treatment choices for low-risk thyroid cancer and related …
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CLINICAL_TRIALS trial_result · 2024-03-22Clinical Trial Update: RAI Plus Immunotherapy for Recurrent/Metastatic Thyroid Cancers [EARLY_Phase 1]
Early-phase (Phase 1) trial update evaluating radioiodine (RAI) plus immunotherapy for recurrent/metastatic thyroid cancer; results were pos…
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CLINICAL_TRIALS trial_result · 2024-01-12Clinical Trial Update: A Phase I/II Study of MLN0128 in Metastatic Anaplastic Thyroid Cancer and Incurably Poorly Differentiated or Radioidodine Refractory Differentiated Thyroid Cancer [Phase 1, Phase 2]
Phase I/II trial of MLN0128 in metastatic anaplastic thyroid cancer and poorly differentiated or radioiodine-refractory differentiated thyro…
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CLINICAL_TRIALS trial_result · 2023-11-28Clinical Trial Update: Famitinib in Combination With Adebrelimab for the Treatment of Advanced Thyroid Cancer [Phase 2]
Phase 2 trial evaluating famitinib in combination with adequreblimab for advanced thyroid cancer.
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CLINICAL_TRIALS trial_result · 2023-11-15Clinical Trial Update: A Study Using Regorafenib as Second or Third Line Therapy in Metastatic Medullary Thyroid Cancer [Phase 2]
Phase 2 study assessing regorafenib as second or third line therapy for metastatic medullary thyroid carcinoma; results have been posted.