Thrombosis
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CLINICAL_TRIALS research · 2013-09-24Clinical Trial Update: ThrombElastoGraphic Haemostatic Status and Antiplatelet Therapy After Coronary Artery Bypass Graft Surgery [Phase 3]
Phase 3 clinical trial evaluating thromboelastographic haemostatic status and antiplatelet therapy after coronary artery bypass graft surger…
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CLINICAL_TRIALS trial_result · 2013-08-01Clinical Trial Update: CompariSon of Manual Aspiration With Rheolytic Thrombectomy in Patients Undergoing Primary PCI. The SMART-PCI Trial [Phase 4]
Clinical trial update on the SMART-PCI Phase 4 study comparing manual aspiration thrombectomy with rheolytic thrombectomy in patients underg…
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CLINICAL_TRIALS trial_result · 2013-06-24Clinical Trial Update: Platelet Hyperreactivity to Aspirin and Stroke [Phase 4]
Phase 4 clinical trial update examining platelet hyperreactivity to aspirin and its relation to stroke outcomes. The study touches broader v…
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CLINICAL_TRIALS trial_result · 2013-06-21Clinical Trial Update: Pharmacogenetics of Acenocoumarol
This completed clinical trial investigates pharmacogenetic factors influencing acenocoumarol response and dosing in thromboembolic diseases.…
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CLINICAL_TRIALS trial_result · 2013-06-17Clinical Trial Update: Plasma Vitamin and Homocysteine Levels and Thrombosis in Patients With Ph-negative MPNs
This clinical trial update reports on plasma vitamin and homocysteine levels and thrombosis in patients with Philadelphia-negative myeloprol…
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CLINICAL_TRIALS research · 2013-05-10Clinical Trial Update: Evaluating the Role of Thrombin in Saphenous Vein Graft Failure After Heart Bypass Surgery
This clinical trial update from the University of Arizona investigates whether thrombin contributes to saphenous vein graft failure after co…
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CLINICAL_TRIALS trial_result · 2013-03-29Clinical Trial Update: Concentrated Citrate Locking to Reduce the Incidence of CVC-related Complications in Hematological Patients [Phase 3]
A Phase 3 trial evaluating whether concentrated citrate locking reduces central venous catheter-related complications in hematological patie…
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CLINICAL_TRIALS trial_result · 2013-02-25Clinical Trial Update: Risk of Developing Antibodies to Heparin-PF4 After Heart Surgery
A completed clinical trial update evaluated the risk of developing antibodies to heparin-PF4 after heart surgery. This immune response is as…
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CLINICAL_TRIALS trial_result · 2013-01-03Clinical Trial Update: Safety Study of Desirudin, an Anticoagulant for the Prophylaxis of Thrombosis [Phase 4]
This document reports results from a Phase 4 safety study of desirudin, an anticoagulant used for the prophylaxis of thrombosis. The study i…
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CLINICAL_TRIALS trial_result · 2012-10-23Clinical Trial Update: Histopathology of the Aspirated Thrombus During Acute Myocardial Infarction
This clinical trial update reports on the histopathology of aspirated thrombus in patients with acute myocardial infarction. It aims to char…
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CLINICAL_TRIALS trial_result · 2012-10-19Clinical Trial Update: Safety, Pharmacokinetic and -Dynamic Study of PR-15, an Inhibitor of Platelet Adhesion [Phase 1]
Phase 1 study evaluating safety, pharmacokinetics and pharmacodynamics of PR-15, a platelet-adhesion inhibitor, in thrombosis and acute coro…
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CLINICAL_TRIALS trial_result · 2012-06-12Clinical Trial Update: Evaluation of Factors II, VII, IX, X, and Proteins C and S, Following High-dose Vitamin K Supplementation [NA]
Completed clinical trial evaluating the effect of high-dose Vitamin K on coagulation factors II, VII, IX, X, and proteins C and S in individ…
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CLINICAL_TRIALS trial_result · 2012-04-25Clinical Trial Update: Evicel Study on the Peri-operative Bleeding in Total Knee Prothesis Surgery [Phase 4]
Phase 4 trial update assessing Evicel (fibrin sealant) for perioperative bleeding in total knee arthroplasty; current status is UNKNOWN.
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CLINICAL_TRIALS research · 2012-04-24Clinical Trial Update: Study in an Ex-vivo Thrombosis Model With Human Umbilical Vein Endothelial Cells (HUVEC)-Perfusion
Clinical trial entry detailing an ex-vivo thrombosis study using human umbilical vein endothelial cells (HUVEC) under perfusion; no clinical…
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CLINICAL_TRIALS trial_result · 2012-01-19Clinical Trial Update: Study of Blood Clotting After Transcatheter Atrial Septal Defect Closure [NA]
This entry provides an update on a clinical trial studying blood clotting after transcatheter closure of an atrial septal defect.
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FDA approval · 2012-01-05FDA Approved: ARGATROBAN — Original Application (Hikma Pharmaceuticals USA Inc.)
FDA approved Hikma Pharmaceuticals USA Inc.'s Argatroban on an Original Application, providing an injectable direct thrombin inhibitor for p…
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CLINICAL_TRIALS trial_result · 2011-12-06Clinical Trial Update: Pilot Dose Finding and Pharmacokinetic Study of Fondaparinux in Children With Thrombosis [Phase 1]
Phase 1 clinical trial assessing dose finding and pharmacokinetics of fondaparinux in pediatric patients with thrombosis, including cases of…
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CLINICAL_TRIALS trial_result · 2011-09-21Clinical Trial Update: STRATAGEM: Strategy for Managing Antiplatelet Therapy in the Perioperative Period of Non Coronary Surgery [Phase 4]
A Phase 4 clinical trial update on strategies for managing antiplatelet therapy around non-coronary surgery; status completed.
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CLINICAL_TRIALS trial_result · 2011-09-16Clinical Trial Update: Anticoagulant Therapy With Bivalirudin in the Performance of Percutaneous Coronary Intervention in Patients With Heparin-Induced Thrombocytopenia (AT BAT, First Inning) [Phase 3]
Phase 3 trial update evaluating bivalirudin as anticoagulant therapy during percutaneous coronary intervention in patients with heparin-indu…
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CLINICAL_TRIALS trial_result · 2011-08-26Clinical Trial Update: Thrombophilic Risk Factors in Pediatric Patients Diagnosed at the Ha'Emek Medical Center
A completed clinical trial from HaEmek Medical Center assessing thrombophilic risk factors in pediatric patients with thrombosis.
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CLINICAL_TRIALS trial_result · 2011-07-20Clinical Trial Update: Randomized Comparison of Warfarin Dosing Quality Between the Hamilton Nomogram and a Commercial Computer System [Phase 3]
This Phase 3 randomized trial compares the quality of warfarin dosing using the Hamilton Nomogram versus a commercial computer system in pat…
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CLINICAL_TRIALS trial_result · 2011-07-20Clinical Trial Update: Oral Vitamin K for Warfarin Associated Coagulopathy [Phase 3]
A Phase 3 trial evaluating oral vitamin K for warfarin-associated coagulopathy has completed.
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CLINICAL_TRIALS trial_result · 2011-07-14Clinical Trial Update: Erythropoietin and Platelet Activation Markers [Phase 4]
Phase 4 clinical trial at the Medical University of Vienna studied erythropoietin and platelet activation markers in patients with thrombosi…
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CLINICAL_TRIALS trial_result · 2011-04-26Clinical Trial Update: A Prospective Observational Registry of Peripheral Use of AngioJet Rheolytic Thrombectomy With Mid-Length Catheters
A completed prospective observational registry evaluating the peripheral use of AngioJet rheolytic thrombectomy with mid-length catheters in…
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CLINICAL_TRIALS trial_result · 2011-03-15Clinical Trial Update: Etude (Study) Phase I Enox - UnFractionated Heparin (UFH) [Phase 1]
Sanofi-sponsored Phase I trial evaluating unfractionated heparin (UFH) for thrombosis; the study status is completed.