Thrombosis
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CLINICAL_TRIALS trial_result · 2017-02-13Clinical Trial Update: Vascular Cell Activation, Cell-Derived Microparticles and In Vitro Fertilisation, and In Vitro Fertilisation
A completed clinical trial from Poissy-Saint Germain Hospital examined vascular cell activation and cell-derived microparticles in the conte…
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CLINICAL_TRIALS trial_result · 2017-01-06Clinical Trial Update: A Study to Evaluate the Effect of Rifampin on the Single-dose Pharmacokinetics of BMS-986177 in Healthy Subjects [Phase 1]
Phase 1 study evaluating the effect of rifampin on the single-dose pharmacokinetics of BMS-986177 in healthy subjects.
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CLINICAL_TRIALS trial_result · 2016-12-23Clinical Trial Update: Study of Safety and Biomarker Efficacy of TS23 in Healthy Volunteer [Phase 1]
Phase 1 trial update assessing safety and biomarker efficacy of TS23 in healthy volunteers, with relevance to thrombosis and ischemia-relate…
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CLINICAL_TRIALS trial_result · 2016-09-12Clinical Trial Update: A Study to Evaluate the Effect of Co-administration of Itraconazole or Diltiazem on the Pharmacokinetics of BMS-986177 in Healthy Subjects [Phase 1]
Phase 1 trial completed to evaluate the pharmacokinetic interactions between BMS-986177 and co-administered itraconazole or diltiazem in hea…
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CLINICAL_TRIALS trial_result · 2016-09-08Clinical Trial Update: CV004-007 Thrombosis Chamber Study [Phase 1]
Phase 1 study CV004-007 Thrombosis Chamber completed; an update from sponsor Bristol-Myers Squibb.
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CLINICAL_TRIALS trial_result · 2016-07-29Clinical Trial Update: Genetic Architecture of Plasma T-PA and PAI-1
This completed clinical trial update explores the genetic factors that influence plasma levels of tissue-type plasminogen activator (t-PA) a…
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CLINICAL_TRIALS trial_result · 2016-06-07Clinical Trial Update: Reversibility of Apixaban Anticoagulation With the Four Factor Prothrombin Complex Concentrate Kcentra [Phase 1]
Phase 1 trial completed evaluating reversal of apixaban anticoagulation with four-factor prothrombin complex concentrate (Kcentra).
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Postmenopausal Estrogen/Progestin Interventions (PEPI) [Phase 3]
Phase 3 PEPI trial completed. The study evaluated postmenopausal estrogen/progestin interventions for effects on bone health and cardiovascu…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Mechanisms of Pro-Thrombosis in Diabetes Mellitus -- Ancillary to BARI 2D
This document reports the completion of an ancillary study to the BARI 2D trial examining mechanisms of pro-thrombosis in diabetes mellitus.…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Inflammation Markers Over Time in Cardiovascular Disease
NHLBI-sponsored clinical trial evaluating inflammation markers over time in cardiovascular disease has completed.
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Mechanisms Underlying Psychosocial Associations With Ischemic Heart Disease (Kuopio)
A Kuopio-based clinical trial funded by NHLBI investigating psychosocial mechanisms related to ischemic heart disease has completed. The stu…
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CLINICAL_TRIALS trial_result · 2016-04-15Clinical Trial Update: Pharmacokinetics of Low Molecular Weight Heparin in Cancer Patients
A completed clinical trial update detailing the pharmacokinetics of low molecular weight heparin in cancer patients.
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CLINICAL_TRIALS trial_result · 2016-03-21Clinical Trial Update: Clinical Study Assessing Idrabiotaparinux Sodium Injections Once-weekly in Pulmonary Embolism Therapeutic Approach [Phase 3]
Phase 3 clinical study of idrabiotaparinux sodium injections once-weekly for pulmonary embolism has completed.
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CLINICAL_TRIALS trial_result · 2016-03-03Clinical Trial Update: Bioavailability of Apixaban Crushed Tablet [Phase 1]
A Phase 1 study evaluated the bioavailability of crushed apixaban tablets in thrombosis, with results posted after completion.
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CLINICAL_TRIALS trial_result · 2016-02-18Clinical Trial Update: Novel Hemostatic Cardiac Risk Factors in Framingham
An NHLBI-sponsored Framingham clinical trial investigated novel hemostatic factors as cardiac risk factors; the study has completed, examini…
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CLINICAL_TRIALS trial_result · 2016-02-18Clinical Trial Update: Lupus Cohort--Thrombotic Events and Coronary Artery Disease
This update summarizes outcomes from a lupus cohort in a completed trial, focusing on thrombotic events and coronary artery disease.
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CLINICAL_TRIALS trial_result · 2016-02-01Clinical Trial Update: Clinical Assessment of Thrombosis in Children After Heart Surgery
This document provides an update on a clinical trial assessing thrombosis in children after heart surgery. The study status is completed.
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CLINICAL_TRIALS trial_result · 2016-01-26Clinical Trial Update: Partial Thromboplastin Time After 72 Hours of Antithrombotic Prophylaxis Using Unfractionated Heparin [NA]
Completed clinical trial evaluating partial thromboplastin time after 72 hours of antithrombotic prophylaxis with unfractionated heparin in …
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CLINICAL_TRIALS trial_result · 2016-01-15Clinical Trial Update: Partial Thromboplastin Time During the First 24 Hours of Antithrombotic Prophylaxis Using Unfractionated Heparin (UFH) [NA]
This clinical trial update reports on partial thromboplastin time measurements during the first 24 hours of antithrombotic prophylaxis using…
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CLINICAL_TRIALS trial_result · 2015-10-02Clinical Trial Update: A Study to Investigate Biomarkers After Single Doses of Anticoagulants in Healthy Young Male and Healthy Elderly Participants (MK-0000-216 AM1) [Phase 1]
This Phase 1 study investigated biomarker changes after single doses of anticoagulants in healthy young and elderly participants.
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CLINICAL_TRIALS trial_result · 2015-06-12Clinical Trial Update: Heparin and the Reduction of Thrombosis (HART) Trial [NA]
The HART trial assessed whether heparin reduces thrombosis and has completed with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-06-04Clinical Trial Update: Depot-medroxyprogesterone Acetate (DMPA) Contraceptive Method and Metabolism
This clinical trial update reports the completion of a study examining the metabolic effects of Depot-medroxyprogesterone acetate (DMPA) con…
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CLINICAL_TRIALS trial_result · 2015-05-21Clinical Trial Update: Does Low Dose Oral Vitamin K Improve International Normalized Ratio (INR) Stability? [Phase 3]
This document updates on a Phase 3 clinical trial evaluating whether low-dose oral vitamin K improves INR stability in patients with coagula…
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CLINICAL_TRIALS trial_result · 2015-03-10Clinical Trial Update: Aspirin Responsiveness and Outcome in Coronary Artery Bypass Graft (CABG) Surgery
This clinical trial update reports on aspirin responsiveness and outcomes in patients undergoing coronary artery bypass graft surgery, with …
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CLINICAL_TRIALS trial_result · 2015-03-02Clinical Trial Update: Study of the Efficacy and Safety of DU-176b in Preventing Blood Clots in Patients Undergoing Total Hip Replacement [Phase 2]
Phase 2 trial update on DU-176b for preventing blood clots in hip replacement patients; study completed with results posted in 2015.