Thrombocytopenia
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CLINICAL_TRIALS trial_result · 2018-02-22Clinical Trial Update: Chronic Hepatitis C Virus Related Thrombocytopenia to Evaluate the Effects of E5501 [Phase 2]
Phase 2 trial evaluating E5501 for hepatitis C virus–related thrombocytopenia has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-01-30Clinical Trial Update: Efficacy of Sialic Acid GNE Related Thrombocytopenia [Phase 2]
Phase 2 clinical trial update assessing efficacy of sialic acid GNE in thrombocytopenia has completed.
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CLINICAL_TRIALS trial_result · 2018-01-05Clinical Trial Update: Efficacy and Safety of Oral E5501 Plus Standard of Care for the Treatment of Thrombocytopenia in Adults With Chronic Immune Thrombocytopenia (Amendment 02) [Phase 3]
Phase 3 trial update on the efficacy and safety of oral E5501 plus standard of care for adults with chronic immune thrombocytopenia; study c…
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CLINICAL_TRIALS trial_result · 2017-12-12Clinical Trial Update: A Study of Eltrombopag or Placebo in Combination With Azacitidine in Subjects With International Prognostic Scoring System (IPSS) Intermediate-1, Intermediate-2 or High-risk Myelodysplastic Syndromes (MDS) [Phase 3]
Phase 3 trial evaluating eltrombopag or placebo in combination with azacitidine for intermediate-1 to high-risk myelodysplastic syndromes wa…
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CLINICAL_TRIALS research · 2017-12-07Clinical Trial Update: The Effect of Direct Antiviral Therapy on Hepatitis c Virus-related Thrombocytopenia [NA]
A clinical trial is examining how direct-acting antiviral therapy for hepatitis C affects hepatitis C–related thrombocytopenia.
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: The Neonatal Hemorrhagic Risk Assessment in Thrombocytopenia Study
This update announces the completion of a clinical trial assessing neonatal hemorrhagic risk in thrombocytopenia.
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Dose Finding Study Of Oral Eltrombopag In Patients With Sarcoma Receiving Adriamycin And Ifosfamide [Phase 1]
A Phase 1 dose-finding study of oral eltrombopag in sarcoma patients receiving Adriamycin and ifosfamide, focusing on thrombocytopenia; the …
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Eltrombopag/Boceprevir and Eltrombopag/Telaprevir Drug-Drug Interaction Study In Healthy Adult Subjects [Phase 1]
GlaxoSmithKline completed a Phase 1 drug-drug interaction study evaluating eltrombopag with boceprevir and eltrombopag with telaprevir in he…
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CLINICAL_TRIALS research · 2017-10-18Clinical Trial Update: Protocol for the Infusion of Buffy Coat-derived Cryopreserved Platelets in Patients With Severe Thrombocytopenia [Phase 4]
This entry describes a Phase 4 protocol for infusing Buffy Coat-derived cryopreserved platelets to treat severe thrombocytopenia; the trial …
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CLINICAL_TRIALS trial_result · 2017-06-08Clinical Trial Update: Three Immunosuppressive Treatment Regimens for Severe Aplastic Anemia [Phase 2]
Phase 2 trial comparing three immunosuppressive regimens for severe aplastic anemia; results of the study have been posted.
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CLINICAL_TRIALS trial_result · 2017-06-08Clinical Trial Update: Observational Trial of a Therapeutic Platelet Transfusion Regimen
An observational trial evaluating a therapeutic platelet transfusion regimen for patients with acute myeloid leukemia and thrombocytopenia h…
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: Indirect Comparison Between Eltrombopag & Romiplostim
This completed clinical trial update presents an indirect comparison of eltrombopag and romiplostim for thrombocytopenia to assess relative …
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: Meta-analysis - Eltrombopag
A meta-analysis update assessing the efficacy and safety of eltrombopag for thrombocytopenia.
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CLINICAL_TRIALS trial_result · 2017-05-16Clinical Trial Update: Anti-D for Treating Thrombocytopenia in Adults Infected With Hepatitis C Virus With or Without HIV Co-Infection [Phase 4]
Phase 4 trial evaluating Anti-D (Rho(D) immune globulin) for thrombocytopenia in adults with hepatitis C with or without HIV infection; the …
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Romiplostim in Treating Hepatitis C-Infected Patients With Thrombocytopenia [Phase 2]
A Phase 2 trial evaluating romiplostim for thrombocytopenia in hepatitis C-infected patients was terminated.
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CLINICAL_TRIALS trial_result · 2017-03-23Clinical Trial Update: SB-497115 (Oral Thrombopoietin Receptor Agonist) Versus Placebo In Adult Cancer Patients Receiving Chemotherapy [Phase 2]
A Phase 2 trial evaluating SB-497115 versus placebo in adults with cancer receiving chemotherapy has completed. The study targets chemothera…
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CLINICAL_TRIALS trial_result · 2016-11-17Clinical Trial Update: Eltrombopag for Thrombocytopenia in Patients With Relapsed Multiple Myeloma [Phase 2]
Phase 2 trial evaluating eltrombopag for thrombocytopenia in patients with relapsed multiple myeloma was terminated; results were posted in …
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CLINICAL_TRIALS research · 2016-10-27Clinical Trial Update: The International ITP Registry
This entry provides a clinical trial update for the International ITP Registry sponsored by South Eastern Sydney Local Health District, invo…
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CLINICAL_TRIALS withdrawal · 2016-10-24Clinical Trial Update: Siltuximab in Treating Patients With Primary, Post-Polycythemia Vera, or Post-Essential Thrombocythemia Myelofibrosis [EARLY_Phase 1]
Northwestern University’s early-phase trial of siltuximab for myelofibrosis, including primary, post-polycythemia vera, and post-essential t…
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CLINICAL_TRIALS research · 2016-09-20Clinical Trial Update: Platelet Kinetics After Platelet Transfusion for the Placement of a Central Venous Catheter
This clinical trial evaluates platelet kinetics after platelet transfusion during the placement of a central venous catheter.
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CLINICAL_TRIALS trial_result · 2016-08-31Clinical Trial Update: Phase I Study Evaluating TXA127 in Low/Intermediate-1 Risk Myelodysplastic Syndrome and Thrombocytopenia [Phase 1]
A Phase I study of TXA127 in patients with low/intermediate-1 risk myelodysplastic syndromes and thrombocytopenia was terminated.
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CLINICAL_TRIALS safety_alert · 2016-08-10Clinical Trial Update: Drug Utilization and Safety Events Among Children Using Esomeprazole, Other Proton Pump Inhibitors or H2-receptor Antagonists
Clinical trial update describing drug utilization and safety events in children treated with esomeprazole, other proton pump inhibitors, or …
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CLINICAL_TRIALS trial_result · 2016-07-06Clinical Trial Update: Cyclosporine in Treating Patients With Low Blood Counts Caused By Hematologic Cancer [Phase 2]
A Phase 2 trial evaluating cyclosporine for treating low blood counts caused by hematologic cancers has completed.
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CLINICAL_TRIALS trial_result · 2016-06-23Clinical Trial Update: Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluated unrelated hematopoietic stem cell transplantation for several genetic blood cell disorders, i…
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CLINICAL_TRIALS trial_result · 2016-06-14Clinical Trial Update: Patient Plasma Response and Outcome in Septic Shock With Thrombocytopenia Associated Multiple Organ Failure in Children
A pediatric clinical trial evaluated plasma response and outcomes in children with septic shock and thrombocytopenia-associated multiple org…