Tetralogy of Fallot
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Pediatric Ventricle Function Assessment Study
A pediatric clinical trial evaluating right and left ventricular function has completed.
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CLINICAL_TRIALS research · 2024-11-06Clinical Trial Update: MASA Valve Early Feasibility Study [NA]
Clinical trial update for the MASA Valve Early Feasibility Study, currently recruiting for patients with congenital heart defects. The study…
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CLINICAL_TRIALS trial_result · 2024-06-18Clinical Trial Update: Targeting Normoxia in Neonates With Cyanotic Congenital Heart Disease in the Intra-operative and Immediate Post-operative Period [NA]
A neonatal clinical trial targeting normoxia during intraoperative and immediate postoperative periods in cyanotic congenital heart disease …
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CLINICAL_TRIALS trial_result · 2023-10-06Clinical Trial Update: Pediatric REPlAcement of the PulmonaRy ValvE in Tetralogy of Fallot - [NA]
A pediatric trial studying replacement of the pulmonary valve in Tetralogy of Fallot was terminated; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-08-24Clinical Trial Update: The Role of Dexmedetomidine as Myocardial Protector in Pediatric Cardiac Surgery Total Correction of Tetralogy of Fallot [Phase 2, Phase 3]
Clinical trial investigating dexmedetomidine as a myocardial protector in pediatric cardiac surgery for total correction of Tetralogy of Fal…
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CLINICAL_TRIALS research · 2023-08-08Clinical Trial Update: ALTERRA: SAPIEN 3 THV With the Alterra Adaptive Prestent [NA]
Update on the ALTERRA trial evaluating the SAPIEN 3 transcatheter heart valve with the Alterra Adaptive Prestent for pulmonary valve procedu…
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CLINICAL_TRIALS trial_result · 2021-12-02Clinical Trial Update: The Medtronic Harmony™ Transcatheter Pulmonary Valve Clinical Study [NA]
This clinical trial update reports posted results for the Harmony transcatheter pulmonary valve in congenital heart disease and Tetralogy of…
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CLINICAL_TRIALS research · 2019-02-12Clinical Trial Update: French National Registry of Patients With Tetralogy of Fallot and Implantable Cardioverter Defibrillator
A French national registry study enrolling patients with Tetralogy of Fallot who have an implantable cardioverter-defibrillator to collect o…
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CLINICAL_TRIALS trial_result · 2018-07-27Clinical Trial Update: Measures to Lower the Stress Response in Pediatric Cardiac Surgery [Phase 2]
A Phase 2 trial evaluating interventions to reduce the surgical stress response in children undergoing congenital heart surgery has complete…
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CLINICAL_TRIALS research · 2018-06-26Clinical Trial Update: Reoxygenation for Cyanotic Pediatric CHD
A ClinicalTrials.gov update describes a study on reoxygenation for cyanotic pediatric congenital heart disease focusing on Tetralogy of Fall…
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CLINICAL_TRIALS trial_result · 2018-05-04Clinical Trial Update: The Effects of Eplerenone on Markers of Myocardial Fibrosis in Adult Congenital Heart Disease [Phase 4]
Phase 4 trial evaluating the effect of eplerenone on markers of myocardial fibrosis in adults with congenital heart disease; the study was t…
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CLINICAL_TRIALS trial_result · 2018-03-23Clinical Trial Update: A Phase I Study of Dexmedetomidine Bolus and Infusion in Corrective Infant Cardiac Surgery: Safety and Pharmacokinetics [Phase 1]
Phase I trial evaluating safety and pharmacokinetics of dexmedetomidine bolus and infusion in infants undergoing corrective cardiac surgery;…
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CLINICAL_TRIALS research · 2017-07-31Clinical Trial Update: Comparison of RVOT Gradient Under Anaesthesia With Post-operative Gradient in Patients Undergoing TOF Repair
This clinical trial update compares right ventricular outflow tract gradient measured under anesthesia with the postoperative gradient in pa…
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CLINICAL_TRIALS research · 2017-06-16Clinical Trial Update: Retrospective Review of Anesthetic Considerations for Pulmonary Artery Rehabilitation
A retrospective analysis examining anesthetic considerations for pulmonary artery rehabilitation in patients with congenital heart condition…
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CLINICAL_TRIALS trial_result · 2017-03-07Clinical Trial Update: Exercise Training in Adults With Corrected Tetralogy of Fallot [NA]
Update on a completed clinical trial evaluating exercise training in adults with corrected Tetralogy of Fallot.
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CLINICAL_TRIALS trial_result · 2016-10-27Clinical Trial Update: Early Revalvulation After Fallot Repair Improves Clinical Outcome
A clinical trial update indicates that early revalvulation after surgical repair of Tetralogy of Fallot is associated with improved clinical…
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CLINICAL_TRIALS trial_result · 2016-08-22Clinical Trial Update: Examining Developmental Changes in Heart Contractions of Children With Congenital Heart Defects
This clinical trial update reports that the study on developmental changes in heart contractions in children with congenital heart defects h…
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CLINICAL_TRIALS trial_result · 2016-03-14Clinical Trial Update: Pulmonary Artery Repair With Covered Stents [NA]
The trial evaluated repairing the pulmonary artery with covered stents in patients with pulmonary stenosis and/or pulmonary regurgitation (i…
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CLINICAL_TRIALS trial_result · 2016-02-18Clinical Trial Update: Reproduction and Survival After Cardiac Defect Repair
The NHLBI-sponsored clinical trial reports on reproduction and survival outcomes after repair of congenital heart defects; the study has com…
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CLINICAL_TRIALS trial_result · 2016-01-05Clinical Trial Update: Myocardial Protection and Clinical Outcome in Patients Undergoing Tetralogy of Fallot Repair : A Randomized Study of Two Different Cardioplegia Technique [Phase 4]
A Phase 4 randomized study compared two cardioplegia techniques in Tetralogy of Fallot repair and assessed myocardial protection and clinica…
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CLINICAL_TRIALS research · 2015-12-22Clinical Trial Update: Right Ventricular Dysfunction in Tetralogy of Fallot: Inhibition of the Renin-angiotensin-aldosterone System [Phase 2]
A Phase 2 clinical trial from AMC-UvA is investigating inhibition of the renin-angiotensin-aldosterone system in patients with Tetralogy of …
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CLINICAL_TRIALS trial_result · 2015-10-29Clinical Trial Update: Multi-center Trial of Percutaneous Pulmonary Valve Implantation With Venus-p [Phase 2, Phase 3]
A multi-center Phase 2/3 trial is evaluating the Venus-p percutaneous pulmonary valve implantation, for patients with pulmonary regurgitatio…
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CLINICAL_TRIALS trial_result · 2015-06-16Clinical Trial Update: Myocardial Contrast Echocardiography in Congenital Heart Disease
A completed clinical trial evaluating myocardial contrast echocardiography in congenital heart disease, focusing on d-transposition of the g…
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CLINICAL_TRIALS trial_result · 2015-06-02Clinical Trial Update: Tetralogy of Fallot Seed Grant
The UCSF-sponsored seed grant trial on pulmonary regurgitation after repair of Tetralogy of Fallot has completed. No specific drug data or r…
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CLINICAL_TRIALS trial_result · 2014-12-02Clinical Trial Update: MRI Assessment of RV Function: Patients With TOF or Aortic Coarctation
A clinical trial update reports on using magnetic resonance imaging to assess right ventricular function in patients with Tetralogy of Fallo…