Temporal Lobe Epilepsy
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CLINICAL_TRIALS research · 2024-07-18Clinical Trial Update: Intensive Preoperative Speech Rehabilitation in Drug-Resistant Temporal Epilepsy [NA]
This clinical trial update describes a study evaluating intensive preoperative speech rehabilitation for patients with drug-resistant tempor…
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CLINICAL_TRIALS trial_result · 2019-11-15Clinical Trial Update: Hippocampal and Thalamic DBS for Bilateral Temporal Lobe Epilepsy [Phase 4]
Phase 4 clinical trial update evaluating hippocampal and thalamic deep brain stimulation for bilateral temporal lobe epilepsy.
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CLINICAL_TRIALS research · 2019-01-22Clinical Trial Update: Advanced Magnetic Resonance Imaging in Temporal Lobe Epilepsy
This document provides an update on a clinical trial investigating advanced magnetic resonance imaging techniques for temporal lobe epilepsy…
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CLINICAL_TRIALS trial_result · 2018-12-07Clinical Trial Update: PRX-00023 Therapy in Localization-Related Epilepsy [Phase 2]
Phase 2 trial update for PRX-00023 in localization-related epilepsy (temporal lobe). Trial status terminated; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2017-07-12Clinical Trial Update: Sabril for Complex Partial Seizures in Adult Tolerability Study (TS) Patients [Phase 4]
A Phase 4 tolerability study of vigabatrin (Sabril) for complex partial seizures was terminated; results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Electrical Brain Stimulation to Reduce Epileptic Seizures
This update notes a completed clinical trial evaluating electrical brain stimulation as a way to reduce seizures in temporal lobe epilepsy.
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CLINICAL_TRIALS research · 2017-07-02Clinical Trial Update: Language and Emotional Function in Patients With Temporal Lobe Epilepsy
This clinical trial update describes language and emotional function outcomes in patients with temporal lobe epilepsy. The study, sponsored …
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CLINICAL_TRIALS withdrawal · 2017-04-28Clinical Trial Update: The Utility of NIOM During LITT for Refractory MTLE [NA]
The clinical trial NCT02913742 exploring NIOM during LITT for refractory mesial temporal lobe epilepsy has been withdrawn.
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CLINICAL_TRIALS research · 2016-06-01Clinical Trial Update: Serum Profile of Inflammatory Factors, Immune and Angiogenic in Temporal Lobe Epilepsy [NA]
A completed clinical trial update investigating serum inflammatory, immune, and angiogenic factors in Temporal Lobe Epilepsy.
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CLINICAL_TRIALS withdrawal · 2016-04-15Clinical Trial Update: Efficacy of TDCS for Treating Working Memory Dysfunction and Depression in Temporal Lobe Epilepsy [Phase 1]
A Phase 1 trial evaluating transcranial direct current stimulation (TDCS) for improving working memory dysfunction and depression in tempora…
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CLINICAL_TRIALS trial_result · 2015-10-29Clinical Trial Update: Application of Diffusion Tensor Imaging and Tractography in Epilepsy Surgery [NA]
This clinical trial update describes the application of diffusion tensor imaging and tractography to assist epilepsy surgery planning in tem…
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CLINICAL_TRIALS trial_result · 2015-07-31Clinical Trial Update: Autologous Bone Marrow Stem Cells Transplantation in Patients With Temporal Lobe Epilepsy [Phase 1]
Phase 1 clinical trial update describing completion of autologous bone marrow stem cell transplantation in patients with temporal lobe epile…
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CLINICAL_TRIALS trial_result · 2015-03-30Clinical Trial Update: CBT Versus Selective Serotonin Reuptake Inhibitor For Treatment Of Depression In Temporal Lobe Epilepsy Patients [NA]
A completed clinical trial comparing cognitive behavioral therapy (CBT) to selective serotonin reuptake inhibitors (SSRIs) for treating depr…
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CLINICAL_TRIALS trial_result · 2012-04-02Clinical Trial Update: A Multicenter Study of Hippocampal Electrical Stimulation (HS, in Mesial Temporal Lobe Epilepsy [Phase 3]
A multicenter Phase 3 study evaluating hippocampal electrical stimulation for temporal lobe epilepsy was terminated.
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CLINICAL_TRIALS trial_result · 2011-07-18Clinical Trial Update: Escitalopram Treatment of Major Depression in Patients With Temporal Lobe Epilepsy [Phase 4]
Phase 4 clinical trial assessing escitalopram for major depressive disorder in patients with temporal lobe epilepsy.
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CLINICAL_TRIALS trial_result · 2010-02-23Clinical Trial Update: Early Surgical Intervention to Treat Epilepsy [Phase 3]
A Phase 3 trial sponsored by UCLA evaluated early surgical intervention for epilepsy, specifically temporal lobe epilepsy. The study status …
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Light Scattering Spectroscopy to Determine Brain Tumors
National Institute of Neurological Disorders and Stroke-funded trial evaluated light scattering spectroscopy as a diagnostic method to deter…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Language Localization Using Repetitive Transcranial Magnetic Stimulation (rTMS) in Patients With Epilepsy
This completed clinical trial investigated using repetitive transcranial magnetic stimulation to assist language localization in patients wi…