Systemic Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of BEN301 Injection in the Treatment of Autoimmune Diseases [EARLY_Phase 1]
Early Phase 1 clinical trial update for BEN301 injection evaluating safety in autoimmune diseases including systemic sclerosis, rheumatoid a…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Study of the Efficacy of Nintedanib+Tocilizumab in Patients With Systemic Sclerosis and Interstitial Lung Disease [Phase 3]
Phase 3 clinical trial evaluating the combination of nintedanib and tocilizumab for systemic sclerosis with interstitial lung disease is cur…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease [Phase 1]
Phase 1 clinical trial update for ALLO-329, an allogeneic CAR T-cell therapy, in adults with autoimmune diseases including systemic lupus er…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study of KITE-363 in Participants With Refractory Autoimmune Diseases [Phase 1]
Phase 1 study evaluating KITE-363 in participants with refractory autoimmune diseases, currently enrolling by invitation, including systemic…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Laser Treatment for the Improvement of Scars and Scleroderma [NA]
A laser treatment trial for improving scars and systemic sclerosis was terminated, with results posted on 2026-04-03 by Massachusetts Genera…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2) [Phase 1, Phase 2]
This is a clinical trial update for a Phase 1/2 study of NKX019 in immune‑mediated diseases, currently recruiting to assess safety and early…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Allogeneic CD19/BCMA CAR-T for B Cell-Related Autoimmune Disease [EARLY_Phase 1]
An early-phase trial of allogeneic CD19/BCMA CAR-T therapy for B-cell–related autoimmune diseases is recruiting at The Children's Hospital o…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Pilot Study to Evaluate the Interest of PDL in the Management of Telangiectasia of the Face and Neckline in Systemic Scleroderma [NA]
A pilot study evaluating Pulsed Dye Laser (PDL) for treating facial telangiectasia in systemic sclerosis has completed.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Study of Nemolizumab for the Treatment of Adults With Systemic Sclerosis [Phase 2]
This is a Phase 2 clinical trial update evaluating nemolizumab for adults with systemic sclerosis; the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: TBI Using IMRT and Cyclophosphamide Prior to Stem Cell Transplant for the Treatment of Severe Systemic Sclerosis [EARLY_Phase 1]
An early-phase trial is evaluating total body irradiation using IMRT and cyclophosphamide prior to stem cell transplant for severe systemic …
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: MRI Quantification of Pulmonary Fibrosis in Scleroderma Patients [NA]
A completed clinical trial evaluating MRI-based quantification of pulmonary fibrosis in patients with systemic sclerosis (scleroderma) to as…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Conception of an ICF Core Set for Systemic Sclerosis
This clinical trial update describes the development of an International Classification of Functioning Core Set for systemic sclerosis, with…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Belimumab and Rituximab Combination Therapy for the Treatment of Diffuse Cutaneous Systemic Sclerosis [Phase 2]
This entry reports a Phase 2 clinical trial evaluating the combination of belimumab and rituximab for diffuse cutaneous systemic sclerosis, …
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Auto-immunity and Pulmonary Arterial Hypertension [NA]
Status update indicating a trial on auto-immunity and pulmonary arterial hypertension sponsored by Assistance Publique - Hôpitaux de Paris i…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Scleroderma: Functional Disability Between the Dominant and Contralateral Hand. [NA]
A completed clinical trial assessing functional disability differences between the dominant and contralateral hand in systemic sclerosis.
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CLINICAL_TRIALS withdrawal · 2026-03-27Clinical Trial Update: Pregnancy and Medically Assisted Conception in Rare Diseases
Clinical trial NCT02450396 on pregnancy and medically assisted conception in rare autoimmune diseases has been withdrawn.
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Phase IIa Trial of Anti-CD19 CAR T-Cells in Systemic Sclerosis Resistant to Immunosuppressive Therapy [Phase 2]
This update announces a Phase IIa clinical trial evaluating anti-CD19 CAR T-cell therapy for systemic sclerosis resistant to immunosuppressi…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Upfront Autologous HSCT Versus Immunosuppression in Early Diffuse Cutaneous Systemic Sclerosis [Phase 4]
A Phase 4 trial comparing upfront autologous hematopoietic stem cell transplantation to immunosuppression in early diffuse cutaneous systemi…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Allogeneic CD19/BCMA-Targeted CAR-γδT Cell Therapy: Safety and Preliminary Pharmacodynamics in Relapsed/Refractory Autoimmune Diseases [Phase 1]
Phase 1 clinical trial update on an allogeneic CD19/BCMA-targeted CAR-γδT cell therapy assessing safety and preliminary pharmacodynamics in …
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Systemic Sclerosis DIet for GastrointESTinal Symptoms [NA]
A recruiting clinical trial at the University of Michigan is evaluating a dietary intervention to manage gastrointestinal symptoms in system…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Double Immunosuppression With or Without Anti-fibrotic in Scleroderma ILD
A clinical trial is evaluating double immunosuppression with or without an anti-fibrotic therapy for systemic sclerosis-associated interstit…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: A Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis [Phase 2]
A Phase 2 multicenter trial assessing HZN-825 in diffuse cutaneous systemic sclerosis has been terminated, with results posted.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Hand Disability In Systemic Sclerosis - Digital Ulcers
Pamukkale University is conducting a clinical trial on hand disability related to digital ulcers in systemic sclerosis, and the study is cur…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Phase 1 Study of Prulacabtagene Leucel (Prula-cel, Formerly ADI-001) in Autoimmune Disease [Phase 1]
Phase 1 trial update for Prulacabtagene Leucel (Prula-cel) in autoimmune diseases, with enrollment by invitation ongoing across indications …
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Hand ScleroDerma Lived Experience Scale in Individuals With Systemic Sclerosis
A clinical trial is evaluating the Hand ScleroDerma Lived Experience Scale in individuals with Systemic Sclerosis to measure hand-related im…