Systemic Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Effectiveness of Tofacitinib in Systemic Sclerosis [Phase 2]
Phase 2 trial update evaluating the effectiveness of tofacitinib in systemic sclerosis; current status is unknown.
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CLINICAL_TRIALS trial_result · 2023-07-27Clinical Trial Update: Mycophenolate in Limited Cutaneous Systemic Sclerosis (MINIMISE-Pilot) [Phase 2]
Phase 2 clinical trial update for mycophenolate in limited cutaneous systemic sclerosis (MINIMISE-Pilot).
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FDA approval · 2023-06-06FDA Approved: TRACLEER — Supplemental Application (Actelion Pharmaceuticals US, Inc.)
The FDA approved a supplemental application for TRACLEER (bosentan) submitted by Actelion Pharmaceuticals US, Inc. This action updates the a…
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CLINICAL_TRIALS trial_result · 2023-05-18Clinical Trial Update: Cold Challenge With C21 in RP [Phase 2]
Phase 2 trial update on C21 for Raynaud Phenomenon and Systemic Sclerosis has completed with results posted.
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CLINICAL_TRIALS research · 2023-02-01Clinical Trial Update: Evaluation of the Scleroderma Patient-centered Intervention Network COVID-19 Home-isolation Activities Together Program [NA]
A completed clinical trial evaluating a home-based intervention for people with scleroderma (systemic sclerosis) undergoing COVID-19 isolati…
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CLINICAL_TRIALS trial_result · 2023-01-17Clinical Trial Update: COvid-19 Vaccine Booster in Immunocompromised Rheumatic Diseases [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial update evaluating a COVID-19 vaccine booster in immunocompromised individuals with rheumatic diseases.
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CLINICAL_TRIALS trial_result · 2022-12-20Clinical Trial Update: A Protocol Based Treatment for Early and Severe Systemic Sclerosis With (Anti-CD20), Rituximab [Phase 2]
Phase 2 trial investigating rituximab (anti-CD20) as a protocol-based treatment for early and severe systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2022-10-12Clinical Trial Update: Safety and Efficacy of Anaerobic Cultivated Human Intestinal Microbiome Transplantation in Systemic Sclerosis (ReSScue) [Phase 2]
Phase 2 trial evaluating anaerobic cultivated human intestinal microbiome transplantation for systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2022-09-29Clinical Trial Update: The Benefit of Bermekimab in Patients With Systemic Sclerosis [Phase 2]
Phase 2 trial update evaluating bermekimab for systemic sclerosis (scleroderma) has completed.
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CLINICAL_TRIALS trial_result · 2022-09-14Clinical Trial Update: Treatment of Systemic Sclerosis With Autologous Regulatory Т-cells [Phase 1, Phase 2]
A clinical trial update investigating autologous regulatory T-cells for systemic sclerosis in Phase 1 and Phase 2, with unknown current stat…
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CLINICAL_TRIALS trial_result · 2022-05-24Clinical Trial Update: Belimumab for the Treatment of Diffuse Cutaneous Systemic Sclerosis [Phase 2]
Phase 2 trial of belimumab for diffuse cutaneous systemic sclerosis completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-03-17Clinical Trial Update: Dimethyl Fumarate (DMF) in Systemic Sclerosis-Associated Pulmonary Arterial Hypertension [Phase 1]
Phase 1 trial of dimethyl fumarate in systemic sclerosis-associated pulmonary arterial hypertension has been terminated; results posted.
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CLINICAL_TRIALS trial_result · 2022-03-15Clinical Trial Update: A Clinical Study to Test Long Term Safety of GLPG1690 for Patients With Systemic Sclerosis [Phase 2]
Phase 2 long-term safety study for GLPG1690 in systemic sclerosis has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2022-02-10Clinical Trial Update: Efficacy of Botulinum Toxin A in Adult Subjects With Raynaud Phenomenon Secondary to Systemic Sclerosis [Phase 3]
Phase 3 trial evaluating the efficacy of Botulinum Toxin A for Raynaud phenomenon secondary to systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2022-02-02Clinical Trial Update: Effectiveness and Safety of SAR156597 in Treating Diffuse Systemic Sclerosis [Phase 2]
Phase 2 trial assessing effectiveness and safety of SAR156597 for diffuse systemic sclerosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-12-01Clinical Trial Update: Evaluation of Effectiveness of Acetylsalicylic Acid on Markers of Vascular Dysfunction in Scleroderma Patients [Phase 4]
Phase 4 trial evaluating acetylsalicylic acid for vascular dysfunction markers in systemic sclerosis (scleroderma) patients has completed.
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CLINICAL_TRIALS trial_result · 2021-09-16Clinical Trial Update: Efficacy and Safety of PLACENTEX ® i.m. in Patients With Scleroderma Diseases [Phase 4]
Phase 4 trial update for PLACENTEX IM in patients with scleroderma, showing termination of the study.
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CLINICAL_TRIALS trial_result · 2021-08-25Clinical Trial Update: Comparing and Combining Bortezomib and Mycophenolate in SSc Pulmonary Fibrosis [Phase 2]
Phase 2 trial evaluating the combination of bortezomib and mycophenolate in interstitial lung disease associated with systemic sclerosis (sc…
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CLINICAL_TRIALS trial_result · 2021-07-30Clinical Trial Update: Prednisolone in Early Diffuse Systemic Sclerosis [Phase 2]
Phase 2 clinical trial update evaluating prednisolone in early diffuse systemic sclerosis has completed.
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FDA approval · 2021-07-29FDA Approved: TRACLEER — Supplemental Application (Actelion Pharmaceuticals US, Inc.)
The FDA approved a supplemental application for TRACLEER (bosentan) from Actelion Pharmaceuticals US, Inc., resulting in labeling changes.
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CLINICAL_TRIALS trial_result · 2021-07-28Clinical Trial Update: Scleroderma Patient-centered Intervention Network (SPIN) Hand Program Feasibility Study [NA]
Feasibility study results for the SPIN Hand Program in scleroderma patients have been completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-07-20Clinical Trial Update: Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory Diseases [Phase 2]
Phase 2 clinical trial evaluating low-dose IL-2 to induce regulatory T cells in various autoimmune and inflammatory diseases; trial complete…
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CLINICAL_TRIALS trial_result · 2021-06-10Clinical Trial Update: Safety and Efficacy of Oral Treprostinil in the Treatment of Calcinosis in Patients With Systemic Sclerosis [Phase 2]
Phase 2 trial evaluating safety and efficacy of oral treprostinil for calcinosis in patients with systemic sclerosis has completed with resu…
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CLINICAL_TRIALS trial_result · 2021-05-24Clinical Trial Update: Proof of Mechanism Study of GSK2330811 in Diffuse Cutaneous Systemic Sclerosis [Phase 2]
Phase 2 proof-of-mechanism study of GSK2330811 in diffuse cutaneous systemic sclerosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-05-21Clinical Trial Update: Efficacy and Tolerability of STI571 (Imatinib Mesylate) for the Treatment of Fibrosis in Participants With Systemic Sclerosis [Phase 2]
Phase 2 trial evaluating imatinib mesylate for systemic sclerosis showed results on efficacy and tolerability.