Systemic Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Efficacy and Safety of Oral Bosentan on Healing/Prevention of Digital (Finger) Ulcers in Patients With Scleroderma [Phase 3]
Phase 3 trial evaluating the efficacy and safety of oral bosentan for healing and prevention of digital ulcers in patients with systemic scl…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Effects of Selexipag in Adults With Raynaud's Phenomenon Secondary to Systemic Sclerosis [Phase 2]
Phase 2 trial evaluating selexipag for Raynaud's phenomenon in adults with systemic sclerosis. The study status is completed.
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Efficacy and Safety of Oral Bosentan in Pulmonary Fibrosis Associated With Scleroderma [Phase 2, Phase 3]
Phase 2/3 trials evaluated the efficacy and safety of oral bosentan for pulmonary fibrosis associated with systemic sclerosis, and the studi…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Open-label Study With Bosentan in Interstitial Lung Disease [Phase 2, Phase 3]
Open-label Phase 2/3 study of bosentan in interstitial lung disease and systemic sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Bosentan in Systemic Sclerosis [Phase 4]
Phase 4 clinical trial evaluating bosentan for systemic sclerosis with digital ulcers has completed.
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CLINICAL_TRIALS research · 2025-01-16Clinical Trial Update: Skeletal Muscle Function in Interstitial Lung Disease [NA]
This ClinicalTrials.gov entry updates an ongoing University of British Columbia study on skeletal muscle function in interstitial lung disea…
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CLINICAL_TRIALS research · 2025-01-15Clinical Trial Update: Ultrasound and Electrophysiology Study of Hand in Systemic Sclerosis Patients and Contributors of Hand Dysfunction
Clinical trial update on ultrasound and electrophysiology study of the hand in patients with systemic sclerosis. The study aims to identify …
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CLINICAL_TRIALS trial_result · 2025-01-10Clinical Trial Update: Vaccination Against Herpes Zoster in Patients With Inflammatory Rheumatic Diseases [Phase 4]
Phase 4 clinical trial is currently enrolling by invitation to evaluate herpes zoster vaccination in patients with inflammatory rheumatic di…
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: Relationship Between Pelvic Floor Dysfunctions and Sexual Dysfunction in Female Patients with Systemic Sclerosis
This clinical trial update describes a study examining the relationship between pelvic floor dysfunction and sexual dysfunction in women wit…
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CLINICAL_TRIALS trial_result · 2025-01-07Clinical Trial Update: Scleroderma Treatment With Autologous Transplant (STAT) Study [Phase 2]
Phase 2 trial results update for autologous hematopoietic stem cell transplantation in systemic sclerosis (STAT) study; results have been po…
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CLINICAL_TRIALS trial_result · 2025-01-06Clinical Trial Update: Use of Selective JAK Inhibitor in ILD and Skin Tightness of Systemic Sclerosis Versus MMF [Phase 3]
Phase 3 clinical trial evaluating a selective JAK inhibitor for interstitial lung disease due to systemic disease and skin tightness in syst…
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: Home Based Clinical Management of Interstitial Lung Disease in Systemic Rheumatic Diseases [NA]
A recruiting clinical trial evaluating home-based clinical management for interstitial lung disease with progressive fibrosing phenotype in …
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: UVA-1 for Treatment of Skin Tightening and Improvement of Hand Function in Scleroderma [NA]
A UVA-1 phototherapy trial is enrolling by invitation to assess its effects on skin tightness and hand function in systemic sclerosis (scler…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: A Phase 1 Study of MEDI7734 in Type I Interferon-Mediated Autoimmune Diseases [Phase 1]
Amgen reported completion of a Phase 1 study of MEDI7734 in Type I interferon-mediated autoimmune diseases, including dermatomyositis, polym…
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CLINICAL_TRIALS research · 2024-12-13Clinical Trial Update: A Study to Evaluate VIB7734 in Participants With Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), Sjogren's Syndrome, Systemic Sclerosis, Polymyositis, and Dermatomyositis [Phase 1]
Amgen's Phase 1 study evaluating VIB7734 in multiple autoimmune diseases including systemic lupus erythematosus, cutaneous lupus erythematos…
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: Phase I/II Randomized Clinical Trial of Allogeneic Adipose Tissue-derived Mesenchymal Stromal Cells Systemic Infusion in Severe Systemic Sclerosis [Phase 1, Phase 2]
Phase I/II randomized clinical trial evaluating systemic infusion of allogeneic adipose tissue-derived mesenchymal stromal cells for severe …
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CLINICAL_TRIALS research · 2024-12-06Clinical Trial Update: Rheumatology Diet Study
A rheumatology dietary intervention study sponsored by the University of Central Florida is currently recruiting, listing multiple autoimmun…
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CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: Impact of Transcutaneous Auricular Vagus Nerve Stimulation on Digestive Symptoms in Systemic Sclerosis Systemic Sclerosis [NA]
Clinical trial update indicates completion of a study evaluating transcutaneous auricular vagus nerve stimulation for digestive symptoms in …
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CLINICAL_TRIALS research · 2024-12-04Clinical Trial Update: PET Imaging of Systemic Sclerosis Using FDG and 68Ga-DOTA-Siglec-9
A clinical trial is evaluating PET imaging of systemic sclerosis using FDG and the radiotracer 68Ga-DOTA-Siglec-9, with enrollment by invita…
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CLINICAL_TRIALS research · 2024-12-04Clinical Trial Update: Phenotyping of Chronic Pain in Diffused Systemic Scleroderma [NA]
A clinical trial investigating chronic pain phenotypes in diffuse cutaneous systemic sclerosis has completed.
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: US Zamto-cel Autoimmune Diseases [Phase 1]
Miltenyi Biomedicine reports a Phase 1 trial of Zamto-cel for autoimmune diseases including lupus nephritis, systemic lupus erythematosus, s…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Development and Evaluation of an Evidence-based Education Program for People With Hand Dysfunction in Scleroderma [NA]
This clinical trial entry describes the development and evaluation of an evidence-based education program for people with hand dysfunction d…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Universal CAR-T Cells (BRL-301) in Relapse or Refractory Autoimmune Diseases [NA]
A clinical trial update shows BRL-301 universal CAR-T cells from Bioray Laboratories enrolling (by invitation) for relapse or refractory aut…
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CLINICAL_TRIALS research · 2024-11-14Clinical Trial Update: Identifying Unique Pathogenic Macrophages in Systemic Sclerosis-ILD
A completed Northwestern University study investigates unique pathogenic macrophages involved in systemic sclerosis-associated interstitial …
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CLINICAL_TRIALS other · 2024-11-12Clinical Trial Update: Respiratory Muscle Training in Scleroderma [NA]
A clinical trial studying respiratory muscle training in systemic sclerosis (scleroderma, limited and diffuse) is not yet recruiting.