Syphilis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Periodic Presumptive Treatment vs. doxyPEP for STI Control in Kenyan MSM [Phase 4]
A Phase 4 trial comparing periodic presumptive treatment to doxycycline post-exposure prophylaxis for STI control among Kenyan men who have …
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: A Cross-sectional Investigational Study to Evaluate the Sensitivity, Specificity, and Utility of the MedMira Inc. Multiplo® Complete Syphilis (TP/nTP) Antibody Test (POCT) to Diagnose Infectious Syphilis in Participants Attending the Sexual Health Clinic in Ottawa, Ontario. [NA]
A ClinicalTrials.gov entry describes a cross-sectional study evaluating the sensitivity, specificity, and utility of the MedMira Multiplo Co…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Comparisons of Treatment Responses of Early Syphilis to Benzathine Penicillin G With or Without Doxycycline [NA]
A clinical trial comparing treatment responses of early syphilis using benzathine penicillin G with or without doxycycline; the study is cur…
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CLINICAL_TRIALS research · 2025-11-03Clinical Trial Update: Modernizing Perinatal Syphilis Testing [NA]
A study to modernize perinatal syphilis testing is currently recruiting, led by The University of Texas Health Science Center, Houston.
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Investigating Point-of-care Diagnostics for Sexually Transmitted Infections and Antimicrobial Resistance in Primary Care in Zimbabwe [NA]
This clinical trial update reports the completion of a study evaluating point-of-care diagnostics for sexually transmitted infections and an…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Congenital and Maternal Point of Care Rapid Testing for Syphilis Study, Uganda
This Uganda-based study evaluates congenital and maternal point-of-care rapid testing for syphilis, and the trial is not yet recruiting.
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: The Integrated Female Sexually Transmitted Infection Testing for HIV Epidemic Control Through PrEP (IN-STEP) Study [NA]
This is a clinical trial update for the IN-STEP study, evaluating integrated STI testing to support HIV epidemic control through PrEP. The t…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Impact of Covid-19 on Syphilis
An observational clinical trial is examining how COVID-19 affects syphilis, including retrospective study components, and is currently not r…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Alternative Antibiotics for Syphilis [Phase 3]
This clinical trial update describes a Phase 3 study evaluating alternative antibiotics for syphilis. The trial is currently ACTIVE_NOT_RECR…
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CLINICAL_TRIALS research · 2025-07-06Clinical Trial Update: The Feasibility of Implementing Syphilis Point-of-care Testing Into a Prenatal Clinic for People Facing Barriers to Care [NA]
A feasibility study assessing implementation of syphilis point-of-care testing in a prenatal clinic for people facing barriers to care; the …
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: Zenyth: Motivational Interviewing-based Telehealth Intervention for Bacterial Sexually Transmitted Infection Screening [NA]
A completed clinical trial from the University of Michigan tested a motivational interviewing-based telehealth intervention to promote scree…
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CLINICAL_TRIALS withdrawal · 2025-06-26Clinical Trial Update: Multiplo Near Patient Non-HCP Study [NA]
The Multiplo Near Patient Non-HCP Study has been withdrawn.
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Daily Doxycycline for Early Syphillis [Phase 2]
A Phase 2 clinical trial sponsored by the University of Washington is evaluating daily doxycycline for early syphilis. The study is currentl…
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CLINICAL_TRIALS trial_result · 2025-05-11Clinical Trial Update: Project MATLINK: Development and Evaluation of a Screening, Brief Intervention, & Referral to Treatment (SBIRT) Program for Opioid Dependent Prisoners and Probationers Transitioning to the Community [NA]
This completed clinical trial evaluated a Screening, Brief Intervention, and Referral to Treatment (SBIRT) program for opioid-dependent pris…
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: Validation of Self Testing Using the INSTI Multiplex HIV1/2 Syphilis Antibody Test [NA]
This is a clinical trial update about validating self-testing using the INSTI Multiplex HIV1/2 and Syphilis antibody test; the study is curr…
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CLINICAL_TRIALS trial_result · 2025-04-04Clinical Trial Update: Superiority of On-demand PrEP Versus PEP on Using Doxycycline for Preventing STI in MSM [Phase 4]
Phase 4 clinical trial compares on-demand PrEP with doxycycline PEP for preventing bacterial sexually transmitted infections in men who have…
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: Cefixime Versus Benzathine Penicillin G in Treatment of Early Syphilis [Phase 4]
A Phase 4 study comparing cefixime to benzathine penicillin G for early syphilis has been terminated.
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: LIMIT Trial - Lidocaine With Intramuscular Injection of Benzathine Penicillin G for Treponema Pallidum Treatment [Phase 3]
Phase 3 clinical trial evaluating lidocaine with intramuscular benzathine penicillin G for Treponema pallidum (syphilis) treatment. The stud…
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: Ayaangwaamiziwin Initiative: Carefulness and Preparedness [NA]
Trial update for the Ayaangwaamiziwin Initiative focusing on point-of-care testing for HIV and syphilis; the study is currently active but n…
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CLINICAL_TRIALS trial_result · 2025-03-14Clinical Trial Update: Oral Amoxicillin Compared to Penicillin G Benzathine for the Treatment of Acquired Syphilis. [Phase 3]
A Phase 3 trial evaluating oral amoxicillin versus penicillin G benzathine for acquired syphilis; the study is currently active but not recr…
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: mLab App Plus: A Randomized Controlled Trial of a Mobile Health (mHealth) Intervention [NA]
A randomized controlled trial evaluated the mLab App Plus mobile health intervention for individuals with HIV infection and related sexually…
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CLINICAL_TRIALS research · 2025-02-17Clinical Trial Update: Cefixime Clinical Trial [Phase 3]
A Phase 3 clinical trial of cefixime is evaluating its use for syphilis and HIV infection. Recruitment is ongoing at the University of South…
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CLINICAL_TRIALS trial_result · 2025-02-12Clinical Trial Update: Oral Doxycycline for the Prevention of Syphilis in Men Who Have Sex with Men (DaDHS) [Phase 4]
Phase 4 study completed evaluating oral doxycycline for prevention of syphilis in men who have sex with men (DaDHS).
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CLINICAL_TRIALS research · 2025-01-24Clinical Trial Update: Peer Delivered HIV/Syphilis Self-Testing With Assisted Partner Notification Services [Phase 2]
Phase 2 clinical trial evaluating peer-delivered HIV and syphilis self-testing with assisted partner notification; currently enrolling by in…
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CLINICAL_TRIALS research · 2024-12-06Clinical Trial Update: Offering Routine and Rapid Point of Care (POC) Syphilis Testing in Pregnant Patients Presenting to the Emergency Department [NA]
This clinical trial update describes offering routine and rapid point-of-care syphilis testing to pregnant patients presenting to the emerge…