Status Epilepticus
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: buRst-supprESsion TO Stop Refractory Status Epilepticus Post-cardiac Arrest [Phase 2]
Phase 2 clinical trial update evaluating burst suppression to stop refractory status epilepticus following cardiac arrest; currently recruit…
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: EEG Monitoring for Refractory Status Epilepticus [NA]
A clinical trial investigating EEG monitoring techniques for patients with refractory status epilepticus is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-04-08Clinical Trial Update: Improving Emergency Management of Status Epilepticus [NA]
The clinical trial evaluating improved emergency management of status epilepticus has completed.
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CLINICAL_TRIALS trial_result · 2025-04-04Clinical Trial Update: Feasibility Study: tDCS for Treatment of Refractory Status Epilepticus [NA]
A feasibility study evaluating transcranial direct current stimulation (tDCS) for refractory status epilepticus has been terminated.
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: LORA-PITA IV General Investigation
Pfizer-sponsored LORA-PITA IV General Investigation in Status Epilepticus has completed and posted results.
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CLINICAL_TRIALS research · 2025-02-14Clinical Trial Update: Status Epilepticus Population Study (STEPS)
The STEPS study is a status epilepticus population trial that is currently recruiting at University Hospital Basel, focusing on epileptic se…
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CLINICAL_TRIALS research · 2025-02-04Clinical Trial Update: Study of Pathophysiology of Status Epilepticus and Dysimmune Encephalitis [NA]
Clinical trial NCT04421846 investigates the pathophysiology of status epilepticus and dysimmune encephalitis and is currently recruiting.
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: The Role of Imaging in the Diagnosis, Management and Prognosis of Possible Non-convulsive Status Epilepticus [NA]
This clinical trial update describes a study examining how imaging techniques (PET, perfusion MRI, perfusion CT) can aid in the diagnosis, m…
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Exogenous Ketone Esters for Refractory Status Epileptics [Phase 2, Phase 3]
A clinical trial update shows ongoing recruitment for a Phase 2/3 study evaluating exogenous ketone esters to treat refractory status epilep…
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: Patient-reported Outcome After Status Epilepticus
A completed clinical trial update assessing patient-reported outcomes and long-term outcomes following status epilepticus, including ICU-rel…
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CLINICAL_TRIALS research · 2024-11-05Clinical Trial Update: Patient-reported Outcome and Patient-reported Experience After Status Epilepticus
The clinical trial from Versailles Hospital is recruiting to assess patient-reported outcomes and patient-reported experience after status e…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: The STatus Epilepticus Prognosis Study
Status Epilepticus Prognosis Study is currently recruiting at London Health Sciences Centre Research Institute and Lawson Research Institute…
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CLINICAL_TRIALS research · 2024-08-23Clinical Trial Update: Assessment of Adults Epidemiological Characteristics of Status Epilepticus in the French West Indies and in French Guiana
This clinical trial update outlines an epidemiological assessment of adults with Status Epilepticus in the French West Indies and in French …
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Rapid-Response EEG in Children With Suspected Status Epilepticus
A pediatric clinical trial is currently recruiting to evaluate rapid-response EEG in children with suspected status epilepticus, including t…
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: Stiripentol for the Treatment of Refractory Status Epilepticus
Clinical trial evaluating stiripentol for refractory status epilepticus has completed.
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Application of tDCS Stimulation in Controlling Refractory Status Epilepticus [NA]
A clinical trial is evaluating transcranial direct current stimulation (tDCS) to control refractory status epilepticus and is currently recr…
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CLINICAL_TRIALS trial_result · 2024-07-12Clinical Trial Update: VIGABatrin in Post-anoxic STATus Epilepticus - Phase IIa [Phase 2]
Phase IIa trial of vigabatrin for post-anoxic status epilepticus has completed and results are posted. The study enrolled patients with elec…
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CLINICAL_TRIALS research · 2024-07-12Clinical Trial Update: The "New" Place of LEVETIRACETAM in the Management of Status Epilepticus in Children
This clinical trial update reports on the use of levetiracetam for managing status epilepticus in children and notes that the study is curre…
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FDA approval · 2024-06-07FDA Approved: LORAZEPAM — Supplemental Application (International Medication Systems, Limited)
FDA approved a supplemental application for lorazepam from International Medication Systems, Limited (ANDA 076150).
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CLINICAL_TRIALS withdrawal · 2024-05-14Clinical Trial Update: To Evaluate the Efficacy, Safety, and Tolerability of Intravenous Ganaxolone Added to Standard of Care in Refractory Status Epilepticus (RSE) [Phase 3]
A Phase 3 study evaluating intravenous ganaxolone added to standard of care for refractory status epilepticus has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-05-07Clinical Trial Update: Safety and Efficacy Study of IV Ganaxolone as Adjuvant Therapy for Established Status Epilepticus (ESE) [Phase 2]
The Phase 2 trial evaluating IV ganaxolone as adjuvant therapy for established status epilepticus has been withdrawn.
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CLINICAL_TRIALS research · 2024-05-07Clinical Trial Update: The Efficacy and Safety of Levetiracetam Versus Fosphenytoin in Convulsive Status Epilepticus [Phase 4]
Phase 4 clinical trial comparing levetiracetam versus fosphenytoin for convulsive status epilepticus, currently enrolling by invitation.
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FDA approval · 2023-10-13FDA Approved: FOSPHENYTOIN SODIUM — Original Application (Sagent Pharmaceuticals)
FDA approved an original generic application for fosphenytoin sodium, enabling a generic version of this anticonvulsant to be marketed by Sa…
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FDA approval · 2023-09-27FDA Approved: LORAZEPAM — Supplemental Application (Aurolife Pharma LLC)
The FDA approved a supplemental application for lorazepam from Aurolife Pharma LLC, enabling the commercialization of a generic Lorazepam pr…
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FDA approval · 2023-07-10FDA Approved: DIAZEPAM — Supplemental Application (Oceanside Pharmaceuticals)
FDA approved a supplemental application for Diazepam from Oceanside Pharmaceuticals.