Squamous Cell Carcinoma of the Head and Neck
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CLINICAL_TRIALS trial_result · 2015-07-29Clinical Trial Update: Performance of PET 18 F-FDG Coupled to CT With Contrast Injection Iodized in the Diagnosis of Early Recurrences of Head and Neck Carcinoma Treated With Concurrent Chemoradiation. Comparison With 18F-FDG PET Coupled With CT Not Injected With Filling CT Standard Injection [NA]
This completed clinical trial compared PET/CT imaging with iodinated contrast versus PET/CT without contrast for detecting early recurrences…
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CLINICAL_TRIALS trial_result · 2015-07-23Clinical Trial Update: A Study of AT-101 in Combination With Docetaxel in Squamous Cell Carcinoma Of The Head and Neck [Phase 2]
Phase 2 study of AT-101 in combination with docetaxel for squamous cell carcinoma of the head and neck was terminated, with results posted i…
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CLINICAL_TRIALS trial_result · 2015-04-21Clinical Trial Update: Study of Lonafarnib in Patients With Recurrent Squamous Cell Carcinoma of the Head and Neck (Study P02530) [Phase 2]
Phase 2 trial of lonafarnib in patients with recurrent squamous cell carcinoma of the head and neck has been terminated.
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CLINICAL_TRIALS withdrawal · 2015-03-10Clinical Trial Update: Effectiveness in Head and Neck Cancer Detection Using Positron Emission Tomography (PET) Insert Device
A clinical trial evaluating the effectiveness of a PET insert device for detecting head and neck cancer was withdrawn.
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CLINICAL_TRIALS trial_result · 2015-03-05Clinical Trial Update: TLR8 Agonist VTX-2337 and Cetuximab in Treating Patients With Locally Advanced, Recurrent, or Metastatic Squamous Cell Cancer of Head and Neck [Phase 1]
Phase 1 trial evaluating the combination of the TLR8 agonist VTX-2337 with cetuximab for locally advanced, recurrent, or metastatic squamous…
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CLINICAL_TRIALS trial_result · 2015-02-11Clinical Trial Update: Cabazitaxel - PF Induction Chemotherapy [Phase 1]
Phase 1 clinical trial update reporting completion of testing for cabazitaxel in combination with PF induction chemotherapy for squamous cel…
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CLINICAL_TRIALS research · 2015-02-02Clinical Trial Update: Hypoxia-based Dose Escalation With Radiochemotherapy in Head and Neck Cancer [NA]
This document shares an update on a clinical trial evaluating hypoxia-based dose escalation with radiochemotherapy for head and neck cancer.…
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CLINICAL_TRIALS trial_result · 2014-10-01Clinical Trial Update: Dose Escalation of Bivatuzumab Mertansine in Patients With Advanced Squamous Cell Carcinoma of the Head and Neck or Esophagus [Phase 1]
Phase 1 dose-escalation study of the antibody-drug conjugate Bivatuzumab mertansine in patients with advanced squamous cell carcinoma of the…
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CLINICAL_TRIALS trial_result · 2014-08-29Clinical Trial Update: Identification of Gene Expression Signature for Panitumumab Sensitivity in Untreated Locally Advanced SCCHN [Phase 2]
Phase 2 trial update investigating a gene expression signature predicting panitumumab sensitivity in untreated locally advanced squamous cel…
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CLINICAL_TRIALS trial_result · 2014-08-29Clinical Trial Update: Prospective, Post Marketing Surveillance Study On Erbitux® (Cetuximab) in Patients With Locally Advanced or Recurrent and/or Metastatic Squamous Cell Cancer of the Head and Neck in Korea
Prospective post-marketing surveillance study of cetuximab (Erbitux) in Korean patients with locally advanced, recurrent, or metastatic squa…
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CLINICAL_TRIALS trial_result · 2014-08-27Clinical Trial Update: Zalutumumab in Non-curable Patients With SCCHN [Phase 2]
Phase 2 clinical trial update for zalutumumab in non-curable head and neck squamous cell carcinoma has completed with results posted.
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CLINICAL_TRIALS withdrawal · 2014-08-19Clinical Trial Update: Concordance of Two Endoscopic Procedures for Diagnosis of Carcinoma of the Upper Aerodigestive Tract [NA]
A clinical trial assessing concordance of two endoscopic procedures for diagnosing carcinoma of the upper aerodigestive tract has been withd…
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CLINICAL_TRIALS trial_result · 2014-08-05Clinical Trial Update: Study of Addition of Panitumumab to Chemoradiation Therapy in Patients With Locally Advanced Head and Neck Cancer [Phase 2]
Phase 2 trial evaluating the addition of panitumumab to chemoradiation in locally advanced head and neck squamous cell carcinoma has complet…
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CLINICAL_TRIALS trial_result · 2014-07-29Clinical Trial Update: EMD 1201081 in Combination With Cetuximab in Second-Line Cetuximab-Naïve Subjects With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck [Phase 2]
Phase 2 trial evaluating EMD 1201081 in combination with cetuximab in second-line, cetuximab-naive recurrent or metastatic squamous cell car…
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CLINICAL_TRIALS trial_result · 2014-07-08Clinical Trial Update: A Post Marketing Surveillance Study of Cetuximab in Patients With Squamous Cell Carcinoma of Head and Neck (SCCHN)
A completed post-marketing surveillance study evaluating cetuximab in patients with squamous cell carcinoma of the head and neck.
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CLINICAL_TRIALS withdrawal · 2014-06-17Clinical Trial Update: EMD 1201081 + 5-FU + Cisplatin + Cetuximab in Subjects With Recurrent / Metastatic Squamous Cell Carcinoma of the Head and Neck [Phase 1]
Phase 1 trial of EMD 1201081 plus 5-FU, cisplatin, and cetuximab in recurrent/metastatic squamous cell carcinoma of the head and neck has be…
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CLINICAL_TRIALS trial_result · 2014-06-09Clinical Trial Update: RAD001 in Combination With Cetuximab and Cisplatin in Recurrent and Metastatic SCCHN [Phase 1, Phase 2]
This clinical trial evaluated everolimus (RAD001) in combination with cetuximab and cisplatin for recurrent and metastatic head and neck can…
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CLINICAL_TRIALS trial_result · 2014-04-30Clinical Trial Update: Cilengitide in Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN) [Phase 1, Phase 2]
A Phase 1/2 trial evaluating cilengitide for recurrent and/or metastatic squamous cell carcinoma of the head and neck has completed with res…
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CLINICAL_TRIALS trial_result · 2014-04-09Clinical Trial Update: Evaluation of Cetuximab (ERBITUX) and Concurrent Carboplatin, Paclitaxel & Radiotherapy in the Management of Patients With Advanced Locoregional Squamous Cell Carcinomas of the Head and Neck (GCC 0442) [Phase 2]
Phase 2 clinical trial evaluating cetuximab with carboplatin, paclitaxel, and radiotherapy for advanced locoregional head and neck squamous …
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CLINICAL_TRIALS trial_result · 2014-02-07Clinical Trial Update: PARTNER: Panitumumab Added to Regimen for Treatment of Head aNd Neck Cancer Evaluation of Response [Phase 2]
Phase 2 trial evaluating panitumumab added to regimen for metastatic or recurrent squamous cell carcinoma of the head and neck has completed…
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CLINICAL_TRIALS trial_result · 2014-01-03Clinical Trial Update: Hematologic Toxicity Observation of the Docetaxel+ Cisplatin+ Fluorouracil (TPF)Medical Protocol
A completed clinical trial evaluating the hematologic toxicity of the TPF regimen (docetaxel, cisplatin, fluorouracil) in squamous cell carc…
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CLINICAL_TRIALS trial_result · 2013-11-21Clinical Trial Update: Phase II Study of Skin Toxicity Dosing of IRESSA (Gefitinib) in Squamous Cell Carcinoma of the Head and Neck [Phase 2]
Phase II trial evaluating skin toxicity–guided dosing of gefitinib (IRESSA) in squamous cell carcinoma of the head and neck. The study is co…
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CLINICAL_TRIALS trial_result · 2013-07-03Clinical Trial Update: Docetaxel in Combination With Zactima (ZD6474) in Patients With Locally Advanced Squamous Cell Carcinoma of the the Head and Neck [Phase 2]
This Phase 2 trial update reports the results of combining docetaxel with vandetanib (Zactima) in locally advanced squamous cell carcinoma o…
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CLINICAL_TRIALS research · 2013-05-21Clinical Trial Update: Randomised Phase II, Cetuximab in Combination With 5FU and Cisplatin or Carboplatin Versus Cetuximab in Combination With Paclitaxel and Carboplatin for Treatment of Patients With Metastatic Squamous Cell Carcinoma of the Head and Neck [Phase 2]
A randomized Phase II trial comparing cetuximab with 5-FU plus either cisplatin or carboplatin versus cetuximab with paclitaxel and carbopla…
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CLINICAL_TRIALS trial_result · 2013-05-06Clinical Trial Update: Combination of Taxotere and Oxaliplatin in Squamous Cell Carcinoma of the Head and Neck [Phase 2]
Phase 2 study evaluating Taxotere (docetaxel) in combination with oxaliplatin for squamous cell carcinoma of the head and neck; the trial wa…