Squamous Cell Carcinoma of the Head and Neck
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CLINICAL_TRIALS trial_result · 2019-07-16Clinical Trial Update: Paclitaxel (Albumin Bound),Bleomycin And Cisplatin Or Carboplatin for Recurrent Or Metastatic Squamous Cell Carcinoma Of The Head And Neck [Phase 2]
Phase 2 clinical trial investigating paclitaxel (albumin-bound) with bleomycin and cisplatin or carboplatin for recurrent or metastatic squa…
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CLINICAL_TRIALS trial_result · 2019-06-10Clinical Trial Update: Talimogene Laherparepvec With Pembrolizumab for Recurrent Metastatic Squamous Cell Carcinoma of the Head and Neck (MASTERKEY232 / KEYNOTE-137) [Phase 1]
A Phase 1 trial evaluating talimogene laherparepvec in combination with pembrolizumab for recurrent metastatic squamous cell carcinoma of th…
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CLINICAL_TRIALS trial_result · 2019-06-06Clinical Trial Update: Erlotinib,Radiation and Cisplatin in Patients With Complete Resected Squamous Cell Carcinoma of the Head and Neck [Phase 3]
Phase 3 trial evaluating erlotinib with radiation and cisplatin in patients with completely resected squamous cell carcinoma of the head and…
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CLINICAL_TRIALS trial_result · 2019-04-29Clinical Trial Update: NC-6004 With 5-FU and Cetuximab for Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck [Phase 1, Phase 2]
Clinical trial update for NC-6004 in combination with 5-FU and cetuximab in recurrent/metastatic squamous cell carcinoma of the head and nec…
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CLINICAL_TRIALS trial_result · 2019-02-18Clinical Trial Update: Hyperbaric Radiation Sensitization of Head and Neck Cancers [Phase 2]
Phase 2 study evaluating hyperbaric oxygen–assisted radiation sensitization in squamous cell carcinoma of the head and neck; no results are …
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CLINICAL_TRIALS trial_result · 2019-01-31Clinical Trial Update: InductionChemo-Radio-Antibody-Treatment [Phase 2]
A Phase 2 trial of induction chemo-radiation-antibody therapy for squamous cell carcinoma of the head and neck has completed.
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CLINICAL_TRIALS trial_result · 2018-07-09Clinical Trial Update: Neoadjuvant Afatinib Window Study in Squamous Cell Carcinoma of the Head and Neck [Phase 2]
The document notes the completion of a Phase 2 neoadjuvant window trial evaluating afatinib in squamous cell carcinoma of the head and neck.
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CLINICAL_TRIALS trial_result · 2018-06-19Clinical Trial Update: Phase II Study of MEDI4736, Tremelimumab, and MEDI4736 in Combination w/ Tremelimumab Squamous Cell Carcinoma of the Head and Neck [Phase 2]
Phase II study evaluating MEDI4736 (durvalumab) with tremelimumab in combination for recurrent/metastatic squamous cell carcinoma of the hea…
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CLINICAL_TRIALS trial_result · 2018-06-18Clinical Trial Update: Phase II Study of MEDI4736 Monotherapy in Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck [Phase 2]
Phase II study results for MEDI4736 monotherapy in recurrent/metastatic PD-L1-positive squamous cell carcinoma of the head and neck have bee…
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CLINICAL_TRIALS trial_result · 2018-06-11Clinical Trial Update: SF1126 in Recurrent or Progressive SCCHN and Mutations in PIK3CA Gene and/or PI-3 Kinase Pathway Genes [Phase 2]
Phase 2 trial of SF1126 in patients with recurrent or progressive squamous cell carcinoma of the head and neck bearing mutations in PIK3CA o…
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FDA approval · 2018-06-05FDA Approved: ERBITUX — Supplemental Application (ImClone LLC)
The FDA approved a supplemental application for ERBITUX (cetuximab) filed by ImClone LLC.
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CLINICAL_TRIALS trial_result · 2018-05-16Clinical Trial Update: Study of PX-866 and Docetaxel in Solid Tumors [Phase 1, Phase 2]
This clinical trial update notes the completion of a Phase 1/2 study of PX-866 with docetaxel in solid tumors, including non-small cell lung…
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Azacitidine and Cisplatin in Patients With Advanced Lung or Head and Neck Cancer [Phase 1]
Phase 1 trial evaluating azacitidine in combination with cisplatin in adults with advanced non-small cell lung cancer or squamous cell carci…
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CLINICAL_TRIALS trial_result · 2018-04-13Clinical Trial Update: The Role of Chromoendoscopy in the Early Detection of Esophageal Cancer in Patients With Prior Head and Neck Cancers [NA]
This clinical trial update reports on a study evaluating chromoendoscopy for early detection of esophageal cancer in patients with prior hea…
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CLINICAL_TRIALS trial_result · 2018-03-21Clinical Trial Update: Safety Study of the Drug MM-151 in Patients With Advanced Solid Tumors Resisting Ordinary Treatment [Phase 1]
A Phase 1 safety study of the investigational drug MM-151 in patients with advanced solid tumors that have resisted standard treatment has c…
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CLINICAL_TRIALS trial_result · 2018-03-02Clinical Trial Update: Taxotere (Docetaxel) New Indication: Squamous Cell Carcinoma of the Head and Neck (SCCHN) Treatment Registration Trial [Phase 3]
A Phase 3 registration trial evaluating Taxotere (docetaxel) for squamous cell carcinoma of the head and neck has completed.
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CLINICAL_TRIALS trial_result · 2018-02-27Clinical Trial Update: A Study Evaluating MM-310 in Patients With Solid Tumors [Phase 1]
This update reports a Phase 1 study evaluating MM-310 in patients with solid tumors. The listed indications include urothelial carcinoma, ga…
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CLINICAL_TRIALS trial_result · 2018-01-23Clinical Trial Update: Treatment of Solid Tumors With Intratumoral Hiltonol® (Poly-ICLC) [Phase 2]
Phase 2 trial evaluating intratumoral Hiltonol (poly-ICLC) for solid tumors was terminated; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-01-05Clinical Trial Update: Cetuximab and Dasatinib in Recurrent Squamous Cell Carcinoma [Phase 2]
Phase 2 trial of cetuximab and dasatinib in recurrent squamous cell carcinoma of the head and neck was terminated; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2017-12-19Clinical Trial Update: Phase II Study of RAD001 Head and Neck Cancer [Phase 2]
Phase II study of RAD001 in head and neck cancer was terminated; results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-12-04Clinical Trial Update: A Study in Ovarian, Non-Small Cell Lung, Prostate, Colorectal, Gastroesophageal Cancers, and Squamous Cell Carcinoma of the Head and Neck [Phase 2]
Phase 2 clinical trial update across multiple cancer types including ovarian, non-small cell lung, prostate, colorectal, gastric/esophageal,…
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CLINICAL_TRIALS research · 2017-11-14Clinical Trial Update: SUPREME-HN A Retrospective Cohort Study of PD-L1 in Recurrent and Metastatic Squamous Cell Carcinoma of Head and Neck (SCCHN)
A retrospective cohort study sponsored by AstraZeneca assesses PD-L1 expression in recurrent and metastatic squamous cell carcinoma of the h…
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CLINICAL_TRIALS research · 2017-10-30Clinical Trial Update: Immunotherapy Study of Evofosfamide in Combination With Ipilimumab [Phase 1]
A Phase 1 clinical trial update on evofosfamide in combination with ipilimumab for cancer treatment. The study targets pancreatic cancer, me…
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: Multimodality Risk Adapted Tx Including Induction Chemo for SCCHN Amenable to Transoral Surgery [Phase 2]
Phase 2 clinical trial evaluating multimodality, risk-adapted treatment that includes induction chemotherapy for squamous cell carcinoma of …
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CLINICAL_TRIALS trial_result · 2017-09-05Clinical Trial Update: Induction Chemotherapy Followed by Cetuximab Plus Definitive Radiotherapy Versus Radiation Plus Cisplatin [Phase 3]
Phase 3 trial comparing induction chemotherapy followed by cetuximab plus radiotherapy versus radiotherapy with cisplatin for head and neck …