Squamous Cell Carcinoma of the Head and Neck
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CLINICAL_TRIALS trial_result · 2025-04-04Clinical Trial Update: Study of XB002 in Subjects With Solid Tumors (JEWEL-101) [Phase 1]
JEWEL-101 is a Phase 1 trial of XB002 in patients with solid tumors, covering multiple indications. The study has completed.
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Study of the Effects of Pembrolizumab in Patients With Advanced Solid Tumors [Phase 2]
Phase 2 study evaluating pembrolizumab in patients with advanced solid tumors, including squamous cell carcinoma of the head and neck, tripl…
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: A Study of NG-641 and Pembrolizumab in Squamous Cell Carcinoma of the Head and Neck [Phase 1]
A Phase 1 study evaluating NG-641 in combination with pembrolizumab for squamous cell carcinoma of the head and neck has completed.
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CLINICAL_TRIALS trial_result · 2025-03-14Clinical Trial Update: SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas [Phase 1]
Phase 1 trial evaluating SL-279252, a PD-1-Fc-OX40L fusion protein, in adults with advanced solid tumors or lymphomas has been completed wit…
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CLINICAL_TRIALS trial_result · 2025-02-28Clinical Trial Update: 1922GCCC: Pembro and Bavituximab for Squamous Cell Carcinoma of Head and Neck [Phase 2]
Phase 2 clinical trial evaluating pembrolizumab in combination with bavituximab for squamous cell carcinoma of the head and neck; results po…
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: Ph1 Study of SL-172154 Administered Intratumorally in Subjects With Squamous Cell Carcinoma of the Head and Neck or Skin [Phase 1]
Phase 1 intratumoral study of SL-172154 in cutaneous squamous cell carcinoma and squamous cell carcinoma of the head and neck was terminated…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Combination of UCPVax Vaccine and Atezolizumab for the Treatment of Human Papillomavirus Positive Cancers (VolATIL) [Phase 2]
A Phase 2 trial (VolATIL) evaluating UCPVax vaccine in combination with atezolizumab for HPV-positive cancers has completed.
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: First Time in Human Study of AZD8701 With or Without Durvalumab in Participants With Advanced Solid Tumours [Phase 1]
This clinical trial update reports the completion of a first-in-human Phase 1 study evaluating AZD8701 with or without durvalumab in adults …
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CLINICAL_TRIALS trial_result · 2024-11-04Clinical Trial Update: Study of MT-6402 in Subjects With Advanced Solid Cancer That Expresses PD-L1 [Phase 1]
Phase 1 study of MT-6402 in PD-L1-expressing advanced solid tumors, including non-small cell lung cancer and squamous cell carcinoma of the …
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CLINICAL_TRIALS trial_result · 2024-11-01Clinical Trial Update: Study of MT-8421 as Monotherapy and in Combination With Nivolumab in Patients With Selected Advanced Solid Cancer Types [Phase 1]
A Phase 1 study evaluating MT-8421 as monotherapy and in combination with nivolumab in selected advanced solid tumors has been terminated. T…
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: A Study of Atezolizumab (Anti-PD-L1 Antibody) as Adjuvant Therapy After Definitive Local Therapy in Patients With High-Risk Locally Advanced Squamous Cell Carcinoma of the Head and Neck [Phase 3]
A Phase 3 trial evaluating atezolizumab as adjuvant therapy after definitive local therapy in high-risk locally advanced squamous cell carci…
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CLINICAL_TRIALS trial_result · 2024-08-16Clinical Trial Update: ASP-1929 Photoimmunotherapy (PIT) Study in Patients With Recurrent Head/Neck Cancer [Phase 2]
Phase 2 clinical trial update for ASP-1929 Photoimmunotherapy in recurrent head and neck cancer indicates the study is active but not curren…
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Study to Test the Safety and Tolerability of PF-07209960 in Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 study of PF-07209960 in advanced or metastatic solid tumors was terminated, with results posted in July 2024.
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CLINICAL_TRIALS trial_result · 2024-07-11Clinical Trial Update: Phase II Study of Tipifarnib in Squamous Head and Neck Cancer With HRAS Mutations [Phase 2]
This entry reports the completion of a Phase II trial of tipifarnib in HRAS-mutant squamous cell carcinoma of the head and neck, with result…
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CLINICAL_TRIALS trial_result · 2024-05-24Clinical Trial Update: A Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Advanced Malignancies [Phase 1]
This Phase 1 trial evaluated the safety and tolerability of immunotherapy combinations across multiple advanced cancers and has completed.
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CLINICAL_TRIALS trial_result · 2024-04-22Clinical Trial Update: FRAIL-IMMUNE (GORTEC 2018-03) - Combination of Durvalumab With Carboplatin/Paclitaxel [Phase 2]
Phase 2 trial of durvalumab combined with Carboplatin/Paclitaxel in squamous cell carcinoma of the head and neck has completed.
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CLINICAL_TRIALS trial_result · 2024-03-05Clinical Trial Update: A Randomized, Double-blind Study to Evaluate the Clinical Effect and Safety of Fucoidan in Patients With Squamous Cell Carcinomas of the Head and Neck [Phase 2]
A phase 2 randomized, double-blind trial evaluating fucoidan for efficacy and safety in patients with squamous cell carcinomas of the head a…
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CLINICAL_TRIALS trial_result · 2023-12-12Clinical Trial Update: Study to Evaluate the Safety and Activity (Including Distribution) of 177Lu-3BP-227 in Subjects With Solid Tumours Expressing Neurotensin Receptor Type 1. [Phase 1]
Phase 1 trial evaluating safety and activity of 177Lu-3BP-227 in solid tumours expressing neurotensin receptor type 1; study terminated with…
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CLINICAL_TRIALS trial_result · 2023-11-13Clinical Trial Update: Valproic Acid Plus Cisplatin and Cetuximab in Recurrent and/or Metastatic Squamous Cell Carcinoma of Head and Neck [Phase 2]
Phase 2 trial evaluating valproic acid in combination with cisplatin and cetuximab for recurrent or metastatic squamous cell carcinoma of th…
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CLINICAL_TRIALS trial_result · 2023-11-03Clinical Trial Update: Biomarker-based Study in R/M SCCHN [Phase 2]
Phase 2 biomarker-based study in recurrent/metastatic squamous cell carcinoma of the head and neck is ongoing with status currently unknown.
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CLINICAL_TRIALS trial_result · 2023-10-12Clinical Trial Update: Study of LN-145/LN-145-S1 Autologous Tumor Infiltrating Lymphocytes in the Treatment of Squamous Cell Carcinoma of the Head & Neck [Phase 2]
A Phase 2 clinical trial evaluating LN-145/LN-145-S1 autologous tumor infiltrating lymphocytes for squamous cell carcinoma of the head and n…
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CLINICAL_TRIALS trial_result · 2023-08-31Clinical Trial Update: Feasibility & Efficacy of Durvalumab+Tremelimumab+RT and Durvalumab+RT in Non-resect. Locally Advanced HPVnegativ HNSCC [Phase 2]
Phase 2 trial assessing feasibility and efficacy of Durvalumab+Tremelimumab+radiation therapy and Durvalumab+radiation therapy in non-resect…
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CLINICAL_TRIALS trial_result · 2023-06-05Clinical Trial Update: SBRT With Cetuximab +/- Docetaxel Followed by Adjuvant Cetuximab +/- Docetaxel in Recurrent, Previously-Irradiated SCCHN [Phase 2]
Phase 2 trial evaluating SBRT with cetuximab, with or without docetaxel, followed by adjuvant cetuximab +/- docetaxel in recurrent, previous…
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CLINICAL_TRIALS trial_result · 2023-05-19Clinical Trial Update: Panitumumab-IRDye800 and 89Zr-Panitumumab in Identifying Metastatic Lymph Nodes in Patients With Squamous Cell Head and Neck Cancer [Phase 1]
Phase 1 clinical trial evaluating Panitumumab-IRDye800 and 89Zr-Panitumumab imaging agents for identifying metastatic lymph nodes in patient…
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CLINICAL_TRIALS trial_result · 2023-04-06Clinical Trial Update: NIVolumab in Subjects With Recurrent or Metastatic Platinum-refrACTORy SCCHN [Phase 3]
Phase 3 trial update for NIVolumab in recurrent/metastatic platinum-refractory squamous cell carcinoma of the head and neck has completed.