Solid Tumors
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Safety and Efficacy of CMD03 CAR T Cell in Children With Relapse or Refractory Solid Tumors [Phase 1]
Phase 1 study evaluating the safety and potential efficacy of CMD03 CAR T cells in pediatric patients with relapsed or refractory solid tumo…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Sirolimus in Combination With Metronomic Chemotherapy in Children With Recurrent and/or Refractory Solid and CNS Tumors [Phase 2]
A Phase 2 clinical trial investigates sirolimus in combination with metronomic chemotherapy in children with recurrent or refractory solid t…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Safety and Preliminary Efficacy of MBS8(1V270) in Cancer Patients With Advanced Solid Tumours [Phase 1]
Phase 1 study of the investigational therapy MBS8(1V270) evaluating safety and preliminary efficacy in patients with advanced solid tumors, …
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Safety of Recombinant Human IL-21-expressing Oncolytic Vaccinia Virus Injection (hV01) in Advanced Tumors [Phase 1]
Phase 1 trial update assessing the safety of hV01, a recombinant IL-21–expressing oncolytic vaccinia virus, in patients with advanced solid …
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: First in Human Study of CDR404 in HLA-A*02:01 Participants With MAGE-A4 Expressing Solid Tumors [Phase 1]
First-in-human Phase 1 trial evaluating CDR404 in HLA-A*02:01 participants with MAGE-A4 expressing solid tumors is currently recruiting. The…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors, the StepByStep Study [Phase 3]
Phase 3 study (StepByStep) evaluating a mobile health and social media–based physical activity intervention in adolescent and young adult ch…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: IN10018 in Combination With RNK08954 for the Treatment of KRASG12D Mutation-Positive Locally Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
Clinical trial update for IN10018 in combination with RNK08954 for KRASG12D mutation-positive locally advanced or metastatic solid tumors; t…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: A Study of BL-M24D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors and Other Solid Tumors [Phase 1]
This document notes a Phase 1 trial of BL-M24D1 in patients with gastrointestinal tumors and other solid tumors, currently recruiting.
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies [Phase 1]
Phase 1 clinical trial update indicating COM503 is being studied in participants with advanced solid tumors, with recruitment ongoing.
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Monitoring of Immunological Mechanisms and Biomarkers Underlying Efficacy of Immunotherapy in Patients With Early Stage Cancer [NA]
This clinical trial update outlines a study evaluating immunological mechanisms and biomarkers related to immunotherapy in patients with ear…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Long-term Follow-up Study for Participants of Kite-Sponsored Interventional Studies Treated With Gene-Modified Cells
This update describes a long-term follow-up study for participants treated with Kite-sponsored gene-modified cell therapies, with enrollment…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer [Phase 1]
This clinical trial update announces the first-in-human, Phase 1 study of ATX-295, an oral inhibitor of KIF18A, in patients with advanced or…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Study of the Effect of Rifampicin on the Pharmacokinetics (PK) of Multiple Doses of Cediranib in Patients With Solid Tumours [Phase 1]
This update outlines a Phase 1 study to assess how Rifampicin affects the pharmacokinetics of multiple doses of Cediranib in patients with s…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: SLV-324 Treatment of Metastatic Solid Tumors [Phase 1]
SLV-324 is being studied in a Phase 1 trial for metastatic solid tumors, and recruitment is ongoing. The sponsor is Solve Therapeutics.
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial evaluating GVV858 as a single agent or in combination with endocrine therapy for hormone receptor-positiv…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001) [Phase 1, Phase 2]
AVZO-1418 is being studied as a single agent and in combination therapy for locally advanced or metastatic solid tumors in a Phase 1/2 trial…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: G-CSF-Induced Bone Pain and Supportive Care Approaches
This Clinical Trial Update discusses strategies to manage G-CSF-induced bone pain and evaluates supportive care approaches in a completed tr…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: First in Human Study of AZD9592 in Solid Tumors [Phase 1]
First-in-human Phase 1 study of AstraZeneca’s AZD9592 in solid tumors is recruiting to evaluate safety, tolerability, and preliminary dosing…
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: A Safety and Antitumor Activity Trial of Immunoradiotherapy Combinations as a Treatment Option for Subjects With Metastatic Solid Tumors [Phase 1, Phase 2]
A Phase 1/Phase 2 trial evaluating immunoradiotherapy combinations for metastatic solid tumors has been terminated.
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: A Study to Evaluate ARV-806 in Adults With Advanced Cancer That Has the KRAS G12D Mutation [Phase 1, Phase 2]
Clinical trial update for ARV-806 evaluating KRAS G12D-mutant advanced solid tumors in adults; Phase 1/2, currently recruiting.
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of MK-3120 in Participants With Advanced Solid Tumors (MK-3120-002) [Phase 1, Phase 2]
This clinical trial update indicates that MK-3120 is being evaluated for safety and efficacy in participants with advanced solid tumors in a…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: A First in Human Study of PLT012 in Participants With Solid Tumor Cancers [Phase 1]
This is a first-in-human Phase 1 study of PLT012 in participants with solid tumors, currently recruiting.
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 study of KSQ-001EX, autologous tumor infiltrating lymphocytes engineered to inactivate SOCS1, being evaluated in select advanced s…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies [Phase 1]
This clinical trial update describes a Phase 1/1B study of ST-01156, a small-molecule RBM39 degrader, in patients with advanced solid tumors…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Pembrolizumab in Combination With Decitabine and Hypofractionated Index Lesion Radiation in Pediatrics and Young Adults [EARLY_Phase 1]
A Phase 1 trial evaluating pembrolizumab in combination with decitabine and hypofractionated radiation in pediatric and young adult patients…