Solid Tumors
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CLINICAL_TRIALS trial_result · 2015-02-12Clinical Trial Update: Dose-finding Adaptive Phase I/IIa Study to Assess Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of IPP-204106N on Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update reports completion of an adaptive dose-finding Phase I/IIa study evaluating IPP-204106N in patients with advanced…
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CLINICAL_TRIALS trial_result · 2015-01-30Clinical Trial Update: An Open-Label Study to Investigate the Pharmacokinetics of Omacetaxine Mepesuccinate [Phase 1]
Open-label Phase 1 pharmacokinetics study of omacetaxine mepesuccinate; the trial completed, investigating PK in hematologic malignancies an…
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CLINICAL_TRIALS trial_result · 2015-01-26Clinical Trial Update: Safety And PK Study Of CVX-060 In Patients With Advanced Solid Tumors [Phase 1]
Phase 1 safety and pharmacokinetic study of CVX-060 in patients with advanced solid tumors has completed and results are posted.
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CLINICAL_TRIALS trial_result · 2015-01-21Clinical Trial Update: To Determine Maximum Tolerated Dose of BAY79-4620 in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 trial completed to determine the maximum tolerated dose of BAY79-4620 in patients with advanced solid tumors.
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CLINICAL_TRIALS trial_result · 2015-01-16Clinical Trial Update: Pharmacokinetic Study of Carboplatin in Pediatric Hematopoietic Stem Cell Transplantation [Phase 2]
This document provides an update on a Phase 2 pharmacokinetic study of carboplatin in pediatric patients undergoing hematopoietic stem cell …
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CLINICAL_TRIALS trial_result · 2015-01-09Clinical Trial Update: Phase I Study of Bevacizumab and Sorafenib Combined With Low Dose Cyclophosphamide in Patients With Refractory Solid Tumors and Leukemia [Phase 1]
Phase I study evaluating bevacizumab plus sorafenib with low-dose cyclophosphamide in patients with refractory solid tumors and leukemia has…
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CLINICAL_TRIALS trial_result · 2015-01-08Clinical Trial Update: Study of MGCD0103 Given Three-Times Weekly in Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma [Phase 1]
Phase 1 trial of MGCD0103 (mocetinostat) given three times weekly in patients with advanced solid tumors or Non-Hodgkin's lymphoma has compl…
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CLINICAL_TRIALS trial_result · 2014-12-03Clinical Trial Update: Safety and Pharmacokinetics of SAR245408 Daily Oral in Patients With Solid Tumors [Phase 1]
This Phase 1 trial update reports the safety and pharmacokinetic profile of daily oral SAR245408 in patients with solid tumors.
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CLINICAL_TRIALS trial_result · 2014-12-02Clinical Trial Update: The Treatment of Lapatinib in Combination With Sorafenib in Patients With Advanced Refractory Solid Tumors [Phase 1]
This Phase 1 trial evaluates the safety and preliminary activity of the combination of lapatinib and sorafenib in patients with advanced ref…
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CLINICAL_TRIALS safety_alert · 2014-11-24Clinical Trial Update: Hearing Loss and Dizziness in Patients Receiving Oxaliplatin for Solid Tumors
The trial update reports cases of hearing loss and dizziness in patients treated with oxaliplatin for solid tumors. This finding highlights …
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CLINICAL_TRIALS trial_result · 2014-11-19Clinical Trial Update: Phase I Abraxane Weekly and Three Weekly Schedule With Vandetanib [Phase 1]
Phase I study assessing weekly and every-3-week Abraxane in combination with Vandetanib for solid tumors has completed.
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CLINICAL_TRIALS trial_result · 2014-10-28Clinical Trial Update: Safety Study of a Cell Penetrating Peptide (p28) to Treat Solid Tumors That Resist Standard Methods of Treatment [Phase 1]
Phase 1 safety study evaluating the cell-penetrating peptide p28 for solid tumors resistant to standard therapies has completed.
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CLINICAL_TRIALS trial_result · 2014-10-23Clinical Trial Update: INCB18424 in Treating Young Patients With Relapsed or Refractory Solid Tumor, Leukemia, or Myeloproliferative Disease [Phase 1]
A Phase 1 pediatric trial of INCB18424 (ruxolitinib) in relapsed or refractory solid tumors, leukemia, or myeloproliferative disorders has c…
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CLINICAL_TRIALS research · 2014-10-08Clinical Trial Update: Safety Study of CD3/CD19 Depleted Haploidentical Stem Cells [Phase 1, Phase 2]
A Phase 1/2 safety study evaluating CD3/CD19 depleted haploidentical stem cell transplants in pediatric patients with acute leukemia, aplast…
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CLINICAL_TRIALS trial_result · 2014-09-29Clinical Trial Update: Phase I/II AZD8931/Paclitaxel in Treatment of Advanced Solid Tumours (Phase I) and Advanced Breast Cancer (Phase II) [Phase 1, Phase 2]
This is a Phase I/II trial evaluating AZD8931 in combination with Paclitaxel for advanced solid tumors and advanced breast cancer. The study…
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CLINICAL_TRIALS trial_result · 2014-09-29Clinical Trial Update: Clinical Study of Oral PI3K/mTOR Inhibitor in Patients With Advanced Refractory Solid Tumors [Phase 1]
A Phase 1 clinical trial of an oral PI3K/mTOR inhibitor in patients with advanced refractory solid tumors has been suspended.
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CLINICAL_TRIALS trial_result · 2014-09-23Clinical Trial Update: AMG 386 Drug-Drug Interaction Study With Paclitaxel [Phase 1]
Phase 1 trial update evaluating the drug-drug interaction of AMG 386 with paclitaxel in patients with advanced solid tumors; the study statu…
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CLINICAL_TRIALS trial_result · 2014-09-19Clinical Trial Update: Study of GO-203-2C Given Intravenously in Patients With Advanced Solid Tumors Including Lymphomas [Phase 1]
The document reports the completion of a Phase 1 study evaluating GO-203-2C given intravenously in patients with advanced solid tumors (incl…
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CLINICAL_TRIALS trial_result · 2014-09-15Clinical Trial Update: A Study of MM-111 in Patients With Advanced, Refractory Her2 Amplified, Heregulin Positive Cancers [Phase 1]
Phase 1 study of MM-111 in advanced, refractory HER2-amplified, heregulin-positive cancers has completed and results were posted.
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CLINICAL_TRIALS research · 2014-08-27Clinical Trial Update: Dose Escalation and Pharmacokinetic Study of Paclitaxel Liposome Injection in Treating Patients With Advanced Solid Tumor After Failure From Conventional Treatments [Phase 4]
Phase 4 clinical trial update evaluating dose escalation and pharmacokinetics of paclitaxel liposome injection in patients with advanced sol…
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CLINICAL_TRIALS research · 2014-08-20Clinical Trial Update: Feasibility Study for Imaging of Peripheral Tumors With a High-Resolution PET Imaging System [NA]
This document reports a completed feasibility study evaluating high-resolution PET imaging for peripheral solid tumors.
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CLINICAL_TRIALS trial_result · 2014-08-08Clinical Trial Update: BI 2536 BS in Patients With Advanced Solid Tumours and Repeated Administration in Patients With Clinical Benefit [Phase 1]
Phase 1 trial update of BI-2536 in patients with advanced solid tumors. The study has completed after repeated administration in patients wh…
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CLINICAL_TRIALS trial_result · 2014-08-07Clinical Trial Update: Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors [Phase 1]
Phase 1 clinical trial evaluating valproic acid in children with recurrent or refractory solid tumors or central nervous system tumors; the …
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CLINICAL_TRIALS trial_result · 2014-07-31Clinical Trial Update: A Phase 1, Open-Label, Dose Escalation Study of ANG1005 in Patients With Advanced Solid Tumors and Metastatic Brain Cancer [Phase 1]
This document reports the completion of a Phase 1, open-label, dose-escalation study of ANG1005 in patients with advanced solid tumors, with…
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CLINICAL_TRIALS trial_result · 2014-07-24Clinical Trial Update: Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid Tumors [Phase 1]
This Phase 1 study evaluated colony-stimulating factors as treatment for children with recurrent or refractory solid tumors. The trial statu…