Solid Tumors
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: GIC-102, Intravenous Allogeneic NK Cells, in Subjects With Advanced Solid Cancers and R/R Hematologic Malignancies [Phase 1, Phase 2]
GIC-102, an intravenously administered allogeneic NK cell therapy, is being evaluated in Phase 1/Phase 2 trials for advanced solid tumors an…
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CLINICAL_TRIALS trial_result · 2024-07-08Clinical Trial Update: GH55 for Advanced Cancers With MAPK Mutations: A Study on Safety and Early Results [Phase 1, Phase 2]
This clinical trial update covers GH55 in Phase 1/2 for advanced solid tumors with MAPK pathway mutations, focusing on safety and early resu…
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CLINICAL_TRIALS research · 2024-07-08Clinical Trial Update: Study of LTC004 Combine With Toripalimab in Patient With Solid Tumors Resistant to Immunotherapy [Phase 2]
An ongoing Phase 2 trial is evaluating LTC004 in combination with toripalimab for patients with advanced solid tumors resistant to immunothe…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: First-In-Human Dose-Escalation Study of STP1002 in Patients With Advanced-Stage Solid Tumors [Phase 1]
This update reports the completion of a first-in-human dose-escalation Phase 1 trial of STP1002 in patients with solid tumors, assessing saf…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Precision Medicine for Patients With Identified Actionable Mutations [Phase 2]
A Phase 2 precision medicine trial for patients with identified actionable mutations in solid tumors, lymphoma, and multiple myeloma was ter…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Leflunomide for the Treatment of Severe COVID-19 in Patients With a Concurrent Malignancy [Phase 1, Phase 2]
This document reports completion and results posting for a Phase 1/2 study evaluating leflunomide as a treatment for severe COVID-19 in pati…
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Phase 1/2a Study of Oral BAL101553 in Adult Patients With Solid Tumors or Glioblastoma or High-grade Glioma [Phase 1, Phase 2]
This ClinicalTrials.gov update reports that results for the Phase 1/2a trial of oral BAL101553 in adults with solid tumors, glioblastoma, an…
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Sym021 in Combination With Either Sym022 or Sym023 or Sym023 and Irinotecan in Patients With Recurrent Advanced Selected Solid Tumor Malignancies [Phase 1]
A Phase 1 trial evaluating Sym021 in combination with Sym022 or Sym023 (and with Irinotecan in some arms) in patients with recurrent advance…
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: Engineered TILs/CAR-TILs to Treat Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating engineered tumor-infiltrating lymphocytes (TILs) and CAR-TILs for advanced solid tumors, sponsored by the …
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: A Phase IB/II Clinical Study of SHR-9839 for Injection Combined With Other Anti-tumor Therapies in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update notes a Phase Ib/II study to evaluate SHR-9839 in combination with other anti-tumor therapies for patients with a…
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CLINICAL_TRIALS trial_result · 2024-06-24Clinical Trial Update: Phase I/II Study of Avelumab in Pediatric Cancer Participants [Phase 1]
A Phase I/II pediatric trial of avelumab in refractory or relapsed solid tumors and lymphoma was terminated, with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-06-24Clinical Trial Update: Durvalumab in HIV-1 Patients With Solid Tumors [Phase 2]
Phase 2 study evaluating durvalumab in HIV-1 infected patients with solid tumors has completed; results have been posted.
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: Development and Application Study of ePRO Software for Managing Cancer Patients Throughout the Treatment Period [NA]
Clinical trials update describing the development and application of an electronic patient-reported outcome (ePRO) software to manage cancer…
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CLINICAL_TRIALS trial_result · 2024-06-20Clinical Trial Update: Study of the Safety and Efficacy of LHC165 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies [Phase 1]
Phase 1 trial evaluating LHC165 alone and with PDR001 in advanced solid tumors; the study has been terminated.
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CLINICAL_TRIALS trial_result · 2024-06-18Clinical Trial Update: Testing AZD9291 as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH-Subprotocol E) [Phase 2]
Phase 2 MATCH subprotocol evaluating AZD9291 (osimertinib) as a targeted treatment for cancers with EGFR genetic changes; the trial is curre…
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CLINICAL_TRIALS trial_result · 2024-06-18Clinical Trial Update: Testing JNJ-42756493 (Erdafitinib) as Potentially Targeting Treatment in Cancers With FGFR Amplifications (MATCH-Subprotocol K1) [Phase 2]
Phase 2 trial evaluating Erdafitinib (JNJ-42756493) for cancers with FGFR amplifications; the study includes advanced and refractory lymphom…
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CLINICAL_TRIALS trial_result · 2024-06-18Clinical Trial Update: A Study of NOX66 and External Beam Radiotherapy in Patients With Metastatic Castration-resistant Prostate Cancer and Other Solid Tumors [Phase 1, Phase 2]
Clinical trial of NOX66 with external beam radiotherapy in metastatic castration-resistant prostate cancer and other solid tumors was termin…
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CLINICAL_TRIALS research · 2024-06-18Clinical Trial Update: Clinical Study of TROP-2 PET/CT for Noninvasive Diagnosis of Solid Tumors [NA]
A clinical trial is evaluating a TROP-2 targeted PET/CT imaging method for noninvasive diagnosis of solid tumors; recruitment is ongoing.
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CLINICAL_TRIALS trial_result · 2024-06-13Clinical Trial Update: Performance Evaluation of Diagnostic Accuracy of PanTum Detect Test for Detection of Solid Tumours in Known Cancer Population and in Cancer Free Population.
This clinical trial update reports the performance evaluation of the PanTum Detect diagnostic test for detecting solid tumors in both people…
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CLINICAL_TRIALS research · 2024-06-07Clinical Trial Update: Study Evaluating ISM8207 in Participants With Advanced Solid Tumors and Relapsed/Refractory B-Cell Lymphoma [Phase 1]
Phase 1 clinical trial evaluating ISM8207 in participants with advanced solid tumors or relapsed/refractory B-cell lymphoma, currently recru…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: First-in-human Study of IO-108 as Single Agent and in Combination With a PD-1 Immune Check Point Inhibitor in Patients With Advanced Solid Tumors [Phase 1]
First-in-human Phase 1 study of IO-108 as a single agent and in combination with a PD-1 inhibitor in adults with advanced solid tumors has c…
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CLINICAL_TRIALS research · 2024-05-28Clinical Trial Update: U87 CART in Treatment of Advanced Solid Tumor [Phase 1]
Phase 1 clinical trial update for U87 CART therapy in adults with advanced solid tumors, including pancreatic cancer; trial status is UNKNOW…
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CLINICAL_TRIALS research · 2024-05-28Clinical Trial Update: Clinical Efficacy of Tumour Treatment Vaccine (TTV) Combined With PD-1 in the Treatment of Relapsed Refractory Advanced Solid Tumours [NA]
A clinical trial evaluating Tumour Treatment Vaccine (TTV) in combination with a PD-1 inhibitor for relapsed/refractory advanced solid tumor…
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CLINICAL_TRIALS trial_result · 2024-05-24Clinical Trial Update: Dose Confirmation and Dose Expansion Phase 1 Study of IO-108 and IO-108 + Anti-PD-1 in Solid Tumors [Phase 1]
Completion of a Phase 1 dose-confirmation and dose-expansion study evaluating IO-108 alone and in combination with an Anti-PD-1 therapy in p…
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CLINICAL_TRIALS research · 2024-05-21Clinical Trial Update: Study of eFT226 in Subjects With Selected Advanced Solid Tumor Malignancies [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating eFT226 in adults with selected advanced solid tumors is currently recruiting.