Solid Tumors
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: Open-Label, Dose-Escalation With Expansion to Assess the Safety, Tolerability, and PK of TRE-515 in Subjects With Solid Tumors [Phase 1]
An open-label Phase 1 trial of TRE-515 in adults with solid tumors to assess safety, tolerability, and pharmacokinetics with dose-escalation…
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: Study of ESG406 in Adults With Solid Tumors [Phase 1]
Phase 1 clinical trial update for ESG406 in adults with locally advanced or metastatic solid tumors. The study is currently recruiting and s…
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CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: 90-Day Mortality After Emergency Department Discharge in Advanced Cancer
The trial update reports 90-day mortality outcomes for patients with cancer after discharge from the emergency department.
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Safety and Tolerability of CMAB017 In Patients With Advanced Solid Tumors [Phase 1]
This clinical trial update notes a Phase 1 study evaluating the safety and tolerability of CMAB017 in patients with advanced solid tumors. T…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: A First-in-Human Dose Escalation and Expansion Study to Evaluate Intratumoral Administration of SAR441000 as Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors [Phase 1]
First-in-human Phase 1 dose-escalation and expansion study of intratumoral SAR441000 as monotherapy and in combination with cemiplimab in pa…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Effect of an Interdisciplinary Shared Decision-Making Intervention on Decisional Conflict in Advanced Cancer Patients Receiving Third-Line Therapy [NA]
A clinical trial update describing an interdisciplinary shared decision-making intervention to reduce decisional conflict in patients with a…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: A Study of NTX-1088, a Monoclonal Antibody Targeting the Poliovirus Receptor (PVR, CD155), as Monotherapy and Combined With Pembrolizumab [Phase 1]
This clinical trial entry describes NTX-1088, a monoclonal antibody targeting CD155, studied as monotherapy and in combination with pembroli…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer [Phase 1]
A first-in-human Phase 1 trial of OnKure's OKI-219 is currently recruiting for advanced solid tumors and breast cancer.
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: The Safety and Dosimetry Study of 177Lu-LNC1004 Injection [Phase 1]
This clinical trial update reports safety and dosimetry findings from a Phase 1 study of the radiopharmaceutical 177Lu-LNC1004 Injection in …
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Romiplostim N01 for the Treatment of Thrombocytopenia Associated With Radiotherapy-Combined Treatment Regimens in Patients With Solid Tumors [Phase 2]
A Phase 2 clinical trial evaluating Romiplostim N01 to treat thrombocytopenia in patients with solid tumors receiving radiotherapy-based reg…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: LEU01101: Safety and Preliminary Efficacy of LEU011 in Solid Tumours. [Phase 1, Phase 2]
Phase 1/2 clinical trial for LEU011 assesses safety and preliminary efficacy in solid tumors; the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Serum IGF-1 and IGF-1Ec in Malignancy Assessment
This clinical trial assesses serum IGF-1 and IGF-1Ec as biomarkers in malignancy; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: A Study of VRN101099 in Patients With HER2-Positive Solid Tumors [Phase 1]
A Phase 1 clinical trial update for VRN101099 in patients with HER2-positive solid tumors, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: Atezolizumab and Tiragolumab in Patients With NSCLC or Advanced Solid Tumors Having Had Prior Treatment With a PD-1 Inhibitor [Phase 2]
Phase 2 trial evaluating atezolizumab plus tiragolumab in patients with non-small cell lung cancer or advanced solid tumors who previously r…
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: Study of ZG005 in Combination With Gecacitinib and Chemotherapy for Participants With Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating ZG005 in combination with Gecacitinib and chemotherapy for advanced solid tumors; the study status is no…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Phase I Clinical Study of YK1101 Injection for the Treatment of Advanced Solid Tumors [Phase 1]
Phase I clinical trial evaluating YK1101 injection for advanced solid tumors is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Granzyme B PET Imaging Drug as a Predictor of Immunotherapy Response to Checkpoint Inhibitors [Phase 1]
Phase 1 results for a Granzyme B PET imaging agent studied as a predictor of response to checkpoint inhibitor immunotherapy in adults with s…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: MoleculAr Profiling for Pediatric and Young Adult Cancer Treatment Stratification 2 [NA]
This clinical trial update notes that the MoleculAr Profiling for Pediatric and Young Adult Cancer Treatment Stratification 2 study is curre…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: A Study of DS-1471a In Subjects With Advanced Solid Tumors [Phase 1]
DS-1471a was evaluated in a Phase 1 study for advanced solid tumors, and the trial has been terminated.
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: Study of RP-6306 With FOLFIRI in Advanced Solid Tumors [Phase 1]
A Phase 1 trial of RP-6306 in combination with FOLFIRI for advanced solid tumors has been terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: A Study of ADRX-0706 in Select Advanced Solid Tumors [Phase 1]
Phase 1 study of ADRX-0706 in select advanced solid tumors is active/not recruiting, evaluating the investigational agent in triple-negative…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: SPH5030 Tablets in Subjects With Advanced Her2-positive Solid Tumors [EARLY_Phase 1]
A clinical trial update states SPH5030 tablets are being investigated in subjects with HER2-positive advanced solid tumors in an early-phase…
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: A Long-term Follow-up Study of Subjects Who Received CRISPR CAR T Cellular Therapies
This document describes a long-term follow-up study involving subjects who received CRISPR-based CAR T cell therapies; the trial is currentl…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: A Study Evaluating the Safety, Pharmacokinetics (PK), and Preliminary Efficacy of ABBV-399 in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 study assessing safety, pharmacokinetics, and preliminary efficacy of ABBV-399 in participants with advanced solid tumors; status is…
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: PLAN Intervention to Enhance Engagement of Latino Cancer Patients in Advanced Care Planning [NA]
Completed clinical trial evaluating PLAN intervention to enhance engagement of Latino cancer patients in advanced care planning; results pos…