Records containing: Solid Tumors
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CLINICAL_TRIALS study record update · 2022-02-02A Phase I/II Study of Metronomic Cyclophosphamide and Oncolytic Poxvirus JX-594 in Patients With Advanced Hormone-receptor Positive and Triple Negative Breast Cancer and Advanced Soft Tissue Sarcoma (METROmaJX)
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CLINICAL_TRIALS study record update · 2022-01-26A Phase 1 Open-label Dose Escalation Study of CGX1321 in Subjects With Advanced Solid Tumors With Expansion in Advanced Gastrointestinal Tumors and Phase 1b Study of CGX1321 in Combination With Pembrolizumab in Subjects With Advanced Colorectal Cancer or in Combination With Encorafenib + Cetuximab in Subjects With BRAFV600E Mutated Advanced Colorectal Cancer
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CLINICAL_TRIALS study record update · 2022-01-25A Phase 1, Randomized, Open-Label, Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors (SNDX-275-0141, MK3475-460/KEYNOTE-460)
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CLINICAL_TRIALS study record update · 2022-01-25High Dose Chemotherapy With Amifostine and Autologous Stem Cell Transplantation for High Risk Relapsed Pediatric Solid Tumors and Brain Tumors
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CLINICAL_TRIALS study record update · 2022-01-19A Phase Ib Study of the Combination of MLN0128 (Dual TORC1/2 Inhibitor) and MLN8237 (Aurora A Inhibitor, Alisertib) in Patients With Advanced Solid Tumors With an Expansion Cohort in Metastatic Triple-negative Breast Cancer (TNBC)
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CLINICAL_TRIALS study record update · 2021-12-22A Phase I Pharmacologic Study of CYC116, an Oral Aurora Kinase Inhibitor, in Patients With Advanced Solid Tumors
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CLINICAL_TRIALS study record update · 2021-12-21The Effect of Dexamethasone on Symptoms in Patients With Advanced Cancer
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CLINICAL_TRIALS study record update · 2021-12-20A Phase I, Open-label, Multiple-ascending Dose Trial to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of Avelumab (MSB0010718C) in Subjects With Metastatic or Locally Advanced Solid Tumors and Expansion to Selected Indications
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CLINICAL_TRIALS study record update · 2021-12-08An Open-Label, Phase 1 Clinical Study to Evaluate the Safety, Tolerability, PK/PD and Preliminary Efficacy of HBM4003 in Combination With Toripalimab in Patients With Advanced HCC and Other Solid Tumors
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CLINICAL_TRIALS study record update · 2021-12-08A Phase 1/2 Study of INCB053914 in Subjects With Advanced Malignancies
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CLINICAL_TRIALS study record update · 2021-12-06A Phase 1/1b, Open Label, Multiple Dose, Dose Escalation and Expansion Study to Investigate the Safety, Pharmacokinetics and Antitumor Activity of the Anti-PD-1 Monoclonal Antibody BGB-A317 in Combination With the PARP Inhibitor BGB-290 in Subjects With Advanced Solid Tumors
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CLINICAL_TRIALS study record update · 2021-11-29The Oral Cavity as a Source of Febrile Neutropenia: An Observational Study in Cancer Patients Treated With Myelosuppressive Chemotherapy
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CLINICAL_TRIALS study record update · 2021-11-18A Phase I/II Clinical Study of Vorinostat in Combination With Etoposide in Pediatric Patients < 21 Years at Diagnosis With Refractory Solid Tumors
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CLINICAL_TRIALS study record update · 2021-11-12An Open-Label Study to Determine the Maximum Tolerated Dose of Oral CEP-37440 Administered as a Single Agent in Patients With Advanced or Metastatic Solid Tumors
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CLINICAL_TRIALS study record update · 2021-11-03Haploidentical Donor Hematopoietic Stem Cell Transplantation
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CLINICAL_TRIALS study record update · 2021-10-06A Phase 1b Multiple Dose Escalation Study of TAB08 in Patients With Advanced Solid Neoplasms
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CLINICAL_TRIALS study record update · 2021-09-30Safety, Pharmacokinetics, and Pharmacodynamics of Escalating Oral Doses of the Arginase Inhibitor INCB001158 (Formerly Known as CB1158) as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumors
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CLINICAL_TRIALS study record update · 2021-09-16Safety and Pharmacokinetics of BPI-9016M in Patients With Advanced Solid Tumors: A Phase Ia Study, Open-label, Dose-escalation Study
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CLINICAL_TRIALS study record update · 2021-09-05A Phase 1b Study of ZN-c3 as a Single Agent in Patients With Solid Tumors
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CLINICAL_TRIALS study record update · 2021-08-19An Open Label, 2 Period, Fixed-sequence Study to Assess the Effect of Savolitinib on the Pharmacokinetics of Oral Midazolam (a CYP450 3A Probe) in Healthy Subjects
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CLINICAL_TRIALS study record update · 2021-07-28A Phase I Multicenter, Open-label, Dose-escalating Clinical and Pharmacokinetic Study of PM00104 Administered Intravenously Over 1 Hour Daily for 5 Days, Every 3 Weeks, to Subjects With Advanced Malignant Solid Tumors or Lymphoma.
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CLINICAL_TRIALS study record update · 2021-07-26A Phase I Study of Single-agent AZD1775 (MK-1775), a Wee1 Inhibitor, in Patients With Advanced Refractory Solid Tumors
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CLINICAL_TRIALS study record update · 2021-07-20Phase I/II Study of a Triplet Combination of CBP501, Pemetrexed and Cisplatin in Patients With Advanced Solid Tumors and in Chemotherapy-naïve Patients With Malignant Pleural Mesothelioma
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CLINICAL_TRIALS study record update · 2021-07-20Phase I Study of Defactinib Combined With Pembrolizumab and Gemcitabine in Patients With Advanced Cancer
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CLINICAL_TRIALS study record update · 2021-06-24Efficacy and Safety of Radiotherapy or Chemotherapy Combined With Microtransplantation in the Treatment of Advanced and Relapsed Solid Tumors