Solid Tumors
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: T Cell Receptor Gene-Engineered T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor [Phase 1]
This Phase 1 clinical trial evaluates a T cell receptor-engineered T cell therapy targeting KRAS mutations in patients with advanced solid t…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: An Open-label, Multi-center, Dose-escalation and Cohort Expansion Phase I/IIa Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic Profile and Efficacy of ACR246 in Patients With Advanced Solid Tumors [Phase 1]
Open-label, multi-center Phase I/IIa dose-escalation study to evaluate the safety, tolerability, pharmacokinetic profile and preliminary eff…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-Positive Cancers. [Phase 2, Phase 3]
This clinical trial update describes Arm 03 of the DETERMINE trial evaluating entrectinib in adults, pediatric, and teenage/young adult pati…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition [Phase 2, Phase 3]
The update notes ongoing recruitment for the DETERMINE trial Arm 02 investigating atezolizumab in adults and pediatric/young adult patients …
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: LIONS (PLK4 Inhibitor in Advanced Solid Tumors) [Phase 1]
An early-phase (Phase 1) trial of an investigational PLK4 inhibitor in patients with advanced solid tumors was terminated; results were post…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating repotrectinib in pediatric and young adult patients with ALK, ROS1, or NTRK1-3 alterations in locally …
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: IMA402 T Cell-Engaging Receptor Molecule (TCER®) in Recurrent and/or Refractory Solid Tumors [Phase 1, Phase 2]
Immatics Biotechnologies reports its TCER molecule IMA402 is being evaluated in Phase 1/2 trials for recurrent and/or refractory solid tumor…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Tumor Molecular Profiling in Early Phase Clinical Trials
The document describes an early-phase clinical trial program using tumor molecular profiling in patients with solid tumors and lymphoma, whi…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Phase Ib/II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Patients With Advanced/Metastatic Solid Tumors [Phase 1, Phase 2]
Phase Ib/II clinical study evaluating HLX43 in combination with serplulimab for advanced/metastatic solid tumors is currently recruiting. Th…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Phase 1 Study of BB102 in Participants With Advanced Solid Tumors [Phase 1]
This clinical trial update notes that BB102 is being studied in a Phase 1 trial for participants with advanced solid tumors and is currently…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Study of CM518D1 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial of CM518D1 in patients with solid tumors is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Patient Perceptions of the Relational Empathy of Healthcare Practitioners From the Department of Emergency Medicine During the COVID-19 Pandemic [NA]
ClinicalTrials.gov update from MD Anderson Cancer Center describing a study on patient perceptions of the relational empathy of emergency de…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies [Phase 1, Phase 2]
Clinical trial update for BT8009-100 in nectin-4 expressing advanced malignancies (Phase 1/2) with status ACTIVE_NOT_RECRUITING.
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: BDB001-102: Open Label Dose Escalation of BDB001 in Combination w Atezolizumab [Phase 1]
An open-label Phase 1 dose-escalation trial of BDB001 in combination with atezolizumab for solid tumors, which has completed.
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: The Effect of Exercise and Nicotinamide Riboside Muscle Health and Insulin Resistance in Survivors of Childhood Cancer [NA]
This clinical trial update describes a study evaluating the effects of exercise and nicotinamide riboside on muscle health and insulin resis…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Formulating Expert Consensus Guidelines in Cancer Care Using the Delphi Method
This clinical trial update from MD Anderson outlines a study to formulate expert consensus cancer care guidelines using the Delphi method; t…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Safety, Tolerability, and Pharmacokinetics of DCR-PDL1 in Adults With Solid Tumors [Phase 1]
This is an ongoing Phase 1 clinical trial evaluating safety, tolerability, and pharmacokinetics of DCR-PDL1 in adults with solid tumors. The…
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CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: A Study to Assess Long-term Safety of Tazemetostat in Adult Participants of All Ages With Any Disease Treated With Tazemetostat in a Previous Clinical Study [Phase 1, Phase 2]
This document reports the completion of a long-term safety study of tazemetostat in adults who previously received the drug in earlier trial…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Indocyanine Green (ICG) Guided Tumor Resection [Phase 1]
This clinical trial entry describes a Phase 1 study evaluating Indocyanine Green (ICG) guided tumor resection in patients with neoplastic di…
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CLINICAL_TRIALS research · 2025-11-03Clinical Trial Update: A Modular Phase 1/2 Study With CT7439 in Participants With Solid Malignancies [Phase 1, Phase 2]
A modular Phase 1/2 clinical trial of CT7439 for solid malignancies is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-10-30Clinical Trial Update: Remote Monitoring in Cancer Care: A Platform Study
Completed results of a Mayo Clinic platform study evaluating remote monitoring in cancer care across head and neck cancer, hematologic malig…
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Advanced Solid Tumors Receiving Intravenous (IV) ABBV-400 as Monotherapy and in Combination With IV Bevacizumab [Phase 1]
A Phase 1 clinical trial update shows ABBV-400 alone or with bevacizumab being studied in adults with advanced solid tumors, including non-s…
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Phase 1/2 Study of Intratumoral Injection of STX-001 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab [Phase 1, Phase 2]
Strand Therapeutics is conducting a Phase 1/2 trial of intratumoral STX-001 in advanced solid tumors, as monotherapy or in combination with …
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: Investigating the Impact of Proactive Palliative Care
A clinical trial update from Memorial Sloan Kettering Cancer Center describes a study on the impact of proactive palliative care for patient…
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CLINICAL_TRIALS trial_result · 2025-10-27Clinical Trial Update: A Study to Assess the Safety, Pharmacokinetics, and Efficacy of Intravenous (IV) ABBV-303, as Monotherapy and in Combination With IV Infused Budigalimab (ABBV-181), in Adults With Advanced Solid Tumors [Phase 1]
Phase 1 study of ABBV-303 alone or in combination with Budigalimab (ABBV-181) in adults with advanced solid tumors has been terminated.