Solid Tumors
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Phase I Study of AT13148, a Novel AGC Kinase Inhibitor [Phase 1]
Phase I study of AT13148, a novel AGC kinase inhibitor, in patients with advanced solid tumors has completed.
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: Study of Samalizumab in Patients With Advanced Cancer [Phase 1]
Phase 1 study of samalizumab in patients with advanced solid tumors has been terminated.
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CLINICAL_TRIALS trial_result · 2018-07-17Clinical Trial Update: A Dose Escalation Study of Adavosertib(MK1775) in Combination With 5-FU or 5-FU/CDDP in Patients With Advanced Solid Tumor (1775-005 [Phase 1]
Phase 1 dose-escalation trial evaluating adavosertib (MK1775) with 5-FU or 5-FU/cisplatin in advanced solid tumors; trial terminated with re…
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: AT13387 in Adults With Refractory Solid Tumors [Phase 1]
Phase 1 trial of AT13387 in adults with refractory solid tumors, including breast cancer, has completed.
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CLINICAL_TRIALS trial_result · 2018-06-28Clinical Trial Update: A Study of Varlitinib in Japanese Subjects With Advanced or Metastatic Solid Tumours [Phase 1]
Phase 1 study of varlitinib in Japanese patients with advanced or metastatic solid tumors, including biliary tract cancer, has completed.
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CLINICAL_TRIALS trial_result · 2018-05-22Clinical Trial Update: A Study of Emactuzumab and RO7009789 Administered in Combination in Participants With Advanced Solid Tumors [Phase 1]
A Phase 1 study evaluating the safety of combining emactuzumab with RO7009789 in patients with advanced solid tumors has completed.
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CLINICAL_TRIALS trial_result · 2018-05-14Clinical Trial Update: A Study of Extended Carfilzomib Therapy for Patients Previously Enrolled in Carfilzomib Treatment Protocols [Phase 2]
A Phase 2 study evaluated extending carfilzomib therapy in patients previously enrolled in carfilzomib treatment protocols. The trial has co…
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: Phase II Study of Stereotactic Body Radiation Therapy Using Tomotherapy for Tumors of the Lung [NA]
Phase II study update on stereotactic body radiation therapy using Tomotherapy for lung tumors; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-05-08Clinical Trial Update: Study Evaluating Neratinib (HKI-272) In Combination With Vinorelbine In Subjects With Solid Tumors And Metastatic Breast Cancer [Phase 1, Phase 2]
Phase 1/2 study evaluating neratinib in combination with vinorelbine for breast cancer and advanced solid tumors has completed enrollment wi…
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CLINICAL_TRIALS trial_result · 2018-04-30Clinical Trial Update: Phase I Study to Assess the Effect of Food on AZD1775 Pharmacokinetics in Patients With Advanced Solid Tumours [Phase 1]
A Phase I trial completed evaluating the effect of food on the pharmacokinetics of AZD1775 in patients with advanced solid tumors.
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CLINICAL_TRIALS trial_result · 2018-04-11Clinical Trial Update: Vorinostat in Children [Phase 1, Phase 2]
Completed Phase 1/2 clinical trial evaluating vorinostat in pediatric patients with relapsed solid tumors, lymphoma, or leukemia.
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CLINICAL_TRIALS trial_result · 2018-04-04Clinical Trial Update: A Dose Escalation Study of RO6874813 in Participants With Locally Advanced or Metastatic Solid Tumors [Phase 1]
A Phase 1 dose-escalation study of RO6874813 was conducted in participants with locally advanced or metastatic solid tumors. The study has c…
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CLINICAL_TRIALS trial_result · 2018-04-03Clinical Trial Update: Belinostat and Isotretinoin in Treating Patients With Solid Tumors That Are Metastatic or That Cannot Be Removed by Surgery [Phase 1]
This article summarizes a Phase 1 clinical trial evaluating belinostat in combination with isotretinoin for adults with solid tumors that ar…
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CLINICAL_TRIALS trial_result · 2018-03-15Clinical Trial Update: Open Label Trial of Perifosine in Patients Currently Being Treated on Perifosine Trials in Solid Tumors or Multiple Myeloma [NA]
This document reports the completion of an open-label trial of perifosine in patients with solid tumors or multiple myeloma, including non-s…
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CLINICAL_TRIALS trial_result · 2018-03-06Clinical Trial Update: A Study to Evaluate Safety, Pharmacokinetics, and Efficacy of RO6895882 in Participants With Advanced and/or Metastatic Solid Tumors [Phase 1]
Phase 1 study evaluating safety, pharmacokinetics, and preliminary efficacy of RO6895882 in participants with advanced and/or metastatic sol…
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CLINICAL_TRIALS trial_result · 2018-02-19Clinical Trial Update: A Study Of The Safety And Tolerability Of HKI-272 Administered Orally To Japanese Subjects With Advanced Solid Tumors [Phase 1]
Phase 1 study assessing safety and tolerability of HKI-272 (neratinib) in Japanese subjects with advanced solid tumors; completed.
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Safety Study of an Immune Response Modifier in Patients With Refractory Solid Organ Tumors [Phase 1]
Phase 1 safety study of an immune response modifier in patients with refractory solid tumors; the trial has completed.
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CLINICAL_TRIALS trial_result · 2017-11-22Clinical Trial Update: Phase 1 Clinical Trial of NPI-0052 in Patients With Advanced Solid Tumor Malignancies or Refractory Lymphoma [Phase 1]
This document reports the completion of a Phase 1 trial of NPI-0052 in patients with advanced solid tumor malignancies or refractory lymphom…
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CLINICAL_TRIALS trial_result · 2017-11-21Clinical Trial Update: To Determine the Food Effect and Bioavailability of Three Formulations of Veliparib in Subjects With Solid Tumors [Phase 1]
Phase 1 study evaluating the effect of food on the absorption and the bioavailability of three Veliparib formulations in subjects with solid…
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CLINICAL_TRIALS trial_result · 2017-11-21Clinical Trial Update: A Study to Assess the Effect of Rifampin on the Metabolism of Navitoclax [Phase 1]
Phase 1 trial update evaluating the effect of rifampin on navitoclax metabolism; the study has completed.
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CLINICAL_TRIALS trial_result · 2017-11-20Clinical Trial Update: A Study of Veliparib in Combination With Carboplatin and Paclitaxel in Japanese Subjects With Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating veliparib in combination with carboplatin and paclitaxel in Japanese subjects with solid tumors has comple…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Combination Study of GSK1120212 With Gemcitabine in Subjects With Solid Tumors [Phase 1]
Phase 1 trial evaluating the combination of trametinib (GSK1120212) and gemcitabine in subjects with solid tumors; the study has completed.
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: A Study of the Safety and Activity of the MEK Inhibitor Given Together With the AKT Inhibitor to Patients With Multiple Myeloma or Solid Tumor Cancers [Phase 1]
Phase 1 study evaluating the safety and activity of combining a MEK inhibitor with an AKT inhibitor in patients with multiple myeloma or sol…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Open-label Study to Investigate the Safety, PK, and Pharmacodynamics of GSK1120212 in Subjects With Solid Tumors or Lymphoma [Phase 1]
Open-label Phase 1 study evaluating the safety, pharmacokinetics, and pharmacodynamics of GSK1120212 (trametinib) in subjects with solid tum…
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CLINICAL_TRIALS trial_result · 2017-10-09Clinical Trial Update: Study of the Safety and Tolerability of IV Infused PG545 in Patients With Advanced Solid Tumours [Phase 1]
Phase 1 study assessing the safety and tolerability of intravenous PG545 (pixatimod) in patients with advanced solid tumors has completed.