Solid Tumors
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-01-02Clinical Trial Update: Trastuzumab Biosimilar (Samfenet®) Plus Treatment of Physician's Choice (TPC) in Patients With HER2-positive Solid Tumor [Phase 2]
Phase 2 trial evaluating a trastuzumab biosimilar (Samfenet) plus physician's choice therapy for HER2-positive solid tumors. Status and resu…
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CLINICAL_TRIALS trial_result · 2019-12-19Clinical Trial Update: Study to Explore the Safety, Tolerability and Efficacy of MK-3475 in Combination With INCB024360 in Participants With Selected Cancers [Phase 1, Phase 2]
Phase 1/2 trial evaluating MK-3475 (pembrolizumab) in combination with INCB024360 in various selected cancers; study completed with results …
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CLINICAL_TRIALS trial_result · 2019-10-28Clinical Trial Update: MM-398 (Nanoliposomal Irinotecan, Nal-IRI) to Determine Tumor Drug Levels and to Evaluate the Feasibility of Ferumoxytol Magnetic Resonance Imaging to Measure Tumor Associated Macrophages and to Predict Patient Response to Treatment [Phase 1]
Phase 1 trial of MM-398 (Nal-IRI) investigates tumor drug levels and feasibility of using ferumoxytol-enhanced MRI to measure tumor-associat…
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CLINICAL_TRIALS trial_result · 2019-10-15Clinical Trial Update: ODM-207 in Patients With Advance Solid Tumours [Phase 1, Phase 2]
Clinical trial update for ODM-207 in patients with advanced solid tumors across Phase 1 and Phase 2 concluded.
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CLINICAL_TRIALS trial_result · 2019-09-20Clinical Trial Update: A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of Alisertib in Participants With Advanced Solid Tumors or Relapsed/Refractory Lymphoma [Phase 1]
Phase 1 study assessing the pharmacokinetic interaction between itraconazole and alisertib in participants with advanced solid tumors or rel…
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CLINICAL_TRIALS trial_result · 2019-09-11Clinical Trial Update: A Phase I Dose-escalation Study of Subcutaneous ALM201 in Patients With Advanced Ovarian Cancer and Other Solid Tumours [Phase 1]
Phase I dose-escalation study of subcutaneous ALM201 in patients with advanced ovarian cancer and other solid tumors; study terminated with …
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CLINICAL_TRIALS trial_result · 2019-08-28Clinical Trial Update: Phase 1 Study to Determine the Effect of Lenvatinib (E7080) on the Pharmacokinetics of Midazolam in Subjects With Advanced Solid Tumors [Phase 1]
Phase 1 study investigating how lenvatinib affects the pharmacokinetics of midazolam in patients with advanced solid tumors; completed with …
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CLINICAL_TRIALS trial_result · 2019-07-23Clinical Trial Update: An Open-label, Multicenter, Multiple Dose, Phase 1 Study to Establish the Maximum Tolerated Dose of E7389 Liposomal Formulation in Patients With Solid Tumors [Phase 1]
Phase 1 study to establish the maximum tolerated dose of E7389 liposomal formulation in patients with solid tumors completed; results posted…
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CLINICAL_TRIALS trial_result · 2019-07-18Clinical Trial Update: Safety Study of Itacitinib (INCB039110) in Combination With Gemcitabine and Nab-Paclitaxel in Subjects With Advanced Solid Tumors [Phase 1, Phase 2]
A safety study of itacitinib in combination with gemcitabine and nab-paclitaxel in advanced solid tumors completed Phase 1/2.
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CLINICAL_TRIALS trial_result · 2019-07-16Clinical Trial Update: Study of Intralesional Administration of MK-4621 (RGT100) in Adult Participants With Advanced or Recurrent Tumors (MK-4621-001/RGT100-001) [Phase 1, Phase 2]
A clinical trial update for intralesional MK-4621 (RGT100) in adults with advanced or recurrent tumors (Phase 1/2) has terminated, with resu…
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CLINICAL_TRIALS trial_result · 2019-07-12Clinical Trial Update: An Open Label Phase II Study Combining Nivolumab and Celecoxib in Patients With Advanced " Cold " Solid Tumors [Phase 2]
An open-label Phase II study evaluating the combination of nivolumab and celecoxib in patients with advanced metastatic solid tumors (descri…
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CLINICAL_TRIALS trial_result · 2019-06-28Clinical Trial Update: A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of GSK2816126 in Subjects With Relapsed/Refractory Diffuse Large B Cell Lymphoma, Transformed Follicular Lymphoma, Other Non-Hodgkin's Lymphomas, Solid Tumors and Multiple Myeloma [Phase 1]
Phase 1 study of GSK2816126 in relapsed/refractory B-cell and solid tumor malignancies terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-06-21Clinical Trial Update: Food Effect Study of Alisertib (MLN8237) in Participants With Advanced Solid Tumors or Lymphomas [Phase 1]
Phase 1 trial update evaluating the food effect of alisertib (MLN8237) in participants with advanced solid tumors or lymphomas; study comple…
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CLINICAL_TRIALS trial_result · 2019-06-21Clinical Trial Update: A Phase 1b Study Of Axitinib In Combination With Crizotinib In Patients With Advanced Solid Tumors [Phase 1]
A Phase 1b study evaluating axitinib in combination with crizotinib in patients with advanced solid tumors has been completed, with results …
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CLINICAL_TRIALS trial_result · 2019-06-14Clinical Trial Update: An Open-Label, Dose-Escalation Study of INCB054329 in Patients With Advanced Malignancies [Phase 1, Phase 2]
Open-label dose-escalation trial of INCB054329 in patients with advanced solid tumors and hematologic malignancies has terminated; results p…
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CLINICAL_TRIALS trial_result · 2019-06-10Clinical Trial Update: Pharmacokinetics Study of Oral Ixazomib (MLN9708) in Relapsed/Refractory Multiple Myeloma and Advanced Solid Tumors Participants With Normal Renal Function or Severe Renal Impairment [Phase 1]
Phase 1 pharmacokinetics study of oral ixazomib (MLN9708) in relapsed/refractory multiple myeloma and advanced solid tumors, including parti…
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CLINICAL_TRIALS trial_result · 2019-05-08Clinical Trial Update: A Study of [14 C]-Pevonedistat in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 study of 14C-labeled pevonedistat in participants with advanced solid tumors has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-05-02Clinical Trial Update: Alisertib (MLN8237) in Combination With Weekly Paclitaxel in East Asian Patients With Advanced Solid Tumors [Phase 1]
Phase 1 trial of alisertib in combination with weekly paclitaxel in East Asian patients with advanced solid tumors and ovarian cancer was te…
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CLINICAL_TRIALS trial_result · 2019-04-05Clinical Trial Update: A Dose Escalation Study of Adavosertib (MK-1775) in Combination With Either Gemcitabine, Cisplatin, or Carboplatin in Adults With Advanced Solid Tumors (MK-1775-001) [Phase 1]
Phase 1 dose-escalation trial of adavosertib (MK-1775) in combination with gemcitabine, cisplatin, or carboplatin in adults with advanced so…
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CLINICAL_TRIALS trial_result · 2019-04-01Clinical Trial Update: Dose Escalation Study With MK-2206 in Patients With Locally Advanced or Metastatic Solid Tumors (MK-2206-002) [Phase 1]
Phase 1 dose-escalation trial of MK-2206 in locally advanced or metastatic solid tumors completed; results posted.
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CLINICAL_TRIALS trial_result · 2019-03-29Clinical Trial Update: A Study to Evaluate the Effect of Itraconazole and Rifampin on the Pharmacokinetics of Talazoparib in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 study evaluating how itraconazole and rifampin affect the pharmacokinetics of talazoparib in patients with advanced solid tumors; re…
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CLINICAL_TRIALS trial_result · 2019-03-26Clinical Trial Update: A Phase I/IIa Open-Label, Dose Escalation and Cohort Expansion Trial of Oral TSR-011 in Patients With Advanced Solid Tumors and Lymphomas [Phase 1, Phase 2]
A Phase I/IIa open-label dose-escalation and expansion study of oral TSR-011 in patients with advanced solid tumors and lymphomas has comple…
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CLINICAL_TRIALS trial_result · 2019-03-25Clinical Trial Update: Safety, Tolerability and Pharmacokinetic (PK) of Concomitant Esomeprazole and Rifampin, and QT Study on Single and Multiple-doses of Alisertib [Phase 1]
Phase 1 trial evaluating safety, tolerability, PK of esomeprazole with rifampin and a QT study for alisertib in solid tumors and lymphoma.
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CLINICAL_TRIALS trial_result · 2019-03-19Clinical Trial Update: Safety and Efficacy Study of Epitope Peptide To Treat HLA-A*24 or A*02-positive Advanced Solid Tumors [Phase 1, Phase 2]
A safety and efficacy study of an epitope peptide for HLA-A*24 or A*02-positive advanced solid tumors has completed Phase 1/Phase 2.
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CLINICAL_TRIALS trial_result · 2019-03-15Clinical Trial Update: A Study of Alisertib (MLN8237) in Adult East Asian Participants With Advanced Solid Tumors or Lymphomas [Phase 1]
A Phase 1 trial of alisertib (MLN8237) in adult East Asian participants with advanced solid tumors or lymphomas has completed with posted re…